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 | Issue Date FY: 2025 ( Subtotal = $12,471,176 ) (Continued on the next page) |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R01NS133584 | Mechanisms of Neurodegeneration in a Nerve Agent Model | 000 | 2 | NIH | 5/29/2025 | $459,000 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R01EB033359 | Ultrasound Imaging and Treatment of Hernia Mesh | 001 | 3 | NIH | 6/24/2025 | $46,710 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R21AI182983 | Deuterium Labeling Mass Spectrometry for Rapid Antimicrobial Susceptibility Testing | 000 | 2 | NIH | 3/26/2025 | $177,705 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R01EB033359 | Ultrasound Imaging and Treatment of Hernia Mesh | 000 | 3 | NIH | 1/14/2025 | $420,404 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R25GM154009 | Empowering Researchers through Evaluation: The Development of Online Educational Modules for Evaluating Biomedical Research Training Programs | 000 | 2 | NIH | 6/23/2025 | $88,582 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R03AI177172 | Defining the virosphere of neglected hematophagous arthropods | 000 | 2 | NIH | 4/22/2025 | $76,500 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R01AG075156 | Role of peroxisome-mitochondrion communication in tissue aging | 000 | 3 | NIH | 4/23/2025 | $274,823 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R01AG075156 | Role of peroxisome-mitochondrion communication in tissue aging | 001 | 3 | NIH | 6/20/2025 | $24,429 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R21AI180686 | Indirect Prevention of High Path Flu Zoonosis through Universal Vaccination | 000 | 2 | NIH | 4/17/2025 | $186,946 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R35GM146854 | Atom-swapping reaction sequences enabled by decarbonylation and decarboxylation | 000 | 4 | NIH | 7/22/2025 | $363,348 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R01HL170104 | PTEX mechanism in malaria parasite effector protein export and host cell subversion | 000 | 3 | NIH | 8/4/2025 | $365,617 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R01DA061172 | Preventing Substance Use Among Youth in Foster Care Through Collaborative Court Appointed Special Advocates(CASA) Brief Intervention | 000 | 1 | NIH | 5/14/2025 | $663,662 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R35GM138243 | Multi-scale computational investigation of functions and mechanisms of protein-RNA phase separation. | 000 | 6 | NIH | 7/17/2025 | $360,925 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R35GM142883 | Peptide backbone modifications to enhance and study protein folding and binding | 000 | 5 | NIH | 5/26/2025 | $363,464 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R35GM143048 | Establishing a Novel Instrumental Model for Elucidating Mitochondrial DNA-Associated Dysfunction and Pathogenicity | 000 | 5 | NIH | 5/13/2025 | $366,102 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R35GM133488 | Atomic-level characterization of self-regulatory mechanisms in large multidomain enzymes | 001 | 8 | NIH | 5/19/2025 | $363,522 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R35GM156461 | Mimics of Enzymes and Antibodies for Glycans and Other Biological Targets | 000 | 1 | NIH | 4/15/2025 | $439,992 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R24OD028748 | Developing second generation SCID pig models: filling the gaps to improve translation of therapeutics in regenerative medicine | 001 | 5 | NIH | 7/30/2025 | $763,121 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R01AI177540 | Influence of prostaglandin E2 on insect innate immune function | 000 | 1 | NIH | 1/17/2025 | $512,581 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | U18FD007901 | ISU Vet-LIRN Infrastructure Grant Proposal | 000 | 3 | FDA | 7/21/2025 | $45,900 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R24OD036201 | Conditional genetics and precision genome editing resources for Zebrafish | 000 | 2 | NIH | 7/23/2025 | $980,756 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R03NS136717 | Transcriptome-Wide Effect of Therapeutic Antisense Oligonucleotides for the Treatment of Spinal Muscular Atrophy | 000 | 2 | NIH | 4/30/2025 | $76,500 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R35GM143074 | Creating a niche for engineered live biotherapeutics | 000 | 5 | NIH | 5/28/2025 | $288,667 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R01AI114720 | Identification of the untranslated sequence elements and virus-host interactions that modulate flavivirus host-specificity | 000 | 7 | NIH | 3/24/2025 | $374,469 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R01DK131162 | Molecular dissection of Hematopoietic Stem Cell specification triggered by inflammatory mediators | 001 | 4 | NIH | 5/9/2025 | $43,269 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R01DK131162 | Molecular dissection of Hematopoietic Stem Cell specification triggered by inflammatory mediators | 000 | 4 | NIH | 3/6/2025 | $389,410 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R21AI187835 | Molecular mechanism of gamete fusion in malaria parasite | 000 | 1 | NIH | 8/6/2025 | $420,750 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R21AI193824 | Disrupting Apicoplast DNA Replication in Plasmodium: Identifying Key Proteases for Antimalarial Therapy | 000 | 1 | NIH | 7/23/2025 | $385,816 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R01AI154458 | Combination nanovaccine-based immunization against influenza virus in the aged: immunity and protection | 000 | 5 | NIH | 2/12/2025 | $632,725 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R01AI182256 | Mosquito extracellular vesicles in malaria parasite killing and immune priming | 000 | 1 | NIH | 2/24/2025 | $648,924 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R01AI043957 | Structural Studies of a T cell Specific Tyrosine Kinase | 002 | 27 | NIH | 8/6/2025 | $535,619 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R01GM120316 | Crosstalk between brassinosteroid and autophagy pathways in the regulation of plant growth and stress responses | 000 | 5 | NIH | 1/27/2025 | $325,530 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R35GM156300 | Investigating labdane-related diterpenoid biosynthesis | 000 | 1 | NIH | 1/27/2025 | $401,595 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R00DE032311 | Determining the mechanism and impact of streptococcal RaS-RiPPs on the human oral microbiome | 000 | 3 | NIH | 7/10/2025 | $249,000 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R35GM150607 | Mechanistic insights into multifaceted roles of coronavirus exoribonuclease complex | 000 | 3 | NIH | 5/27/2025 | $382,500 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | U01NS117284 | Saracatinib and 1400W Counteract Nerve Agents-Induced Long-Term Neurotoxicity | 000 | 5 | NIH | 8/8/2025 | $758,516 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R35GM140876 | Defining mechanisms of diverse CRISPR-Cas complexes | 001 | 5 | NIH | 5/14/2025 | $359,852 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R35GM155200 | Elucidating Context-Specific FERONIA Receptor Kinase Signaling | 000 | 2 | NIH | 7/17/2025 | $368,832 |
| | 2025 | 2025 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | NU58DP007476 | Statewide Delivery of AAEBIs through a Community Hub Model: A Component A Project in Iowa | 00 | 3 | CDC | 6/30/2025 | $225,000 |
| | 2025 | 2024 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R01FD008143 | Analytical method validation to detect and quantify tulathromycin residues in caprine liver | 000 | 1 | FDA | 10/8/2024 | $0 |
| | 2025 | 2024 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R21AI170922 | A functional characterization of Brugia malayi GABA-gated chloride channels: an unexplored target for antifilarial therapeutics | 000 | 2 | NIH | 7/17/2025 | $0 |
| | 2025 | 2024 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | U01FD007683 | Integration of a multi-pronged standardized methodology to identify key diseases and prioritized antimicrobial alternatives in production animals | 000 | 3 | FDA | 3/25/2025 | $0 |
| | 2025 | 2024 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | U01FD007683 | Integration of a multi-pronged standardized methodology to identify key diseases and prioritized antimicrobial alternatives in production animals | 001 | 3 | FDA | 3/26/2025 | $0 |
| | 2025 | 2024 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | H79TI085600 | Region 7 Networking Center for Rural Opioid Technical Assistance and Training | 001 | 2 | SAMHSA | 12/11/2024 | $0 |
| | 2025 | 2024 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | H79SP084308 | Bridging Gaps, Building Futures: Elevating Substance Misuse Prevention Across Region 7 | 000 | 1 | SAMHSA | 2/28/2025 | $0 |
| | 2025 | 2024 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | U01FD007136 | Detection and surveillance of antimicrobial resistance among enteric bacteria from raw retail meat and seafood in Iowa: A NARMS Retail Food Surveillance Project | 000 | 5 | FDA | 11/19/2024 | $0 |
| | 2025 | 2024 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R35GM133488 | Atomic-level characterization of self-regulatory mechanisms in large multidomain enzymes | 000 | 7 | NIH | 11/5/2024 | $0 |
| | 2025 | 2024 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | R01GM133810 | Finding and folding novel RNA structures | 001 | 6 | NIH | 4/28/2025 | $243,810 |
| | 2025 | 2024 | IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | 1350 BEARDSHEAR HALL | AMES | IA | 50011-2103 | STORY | USA | F31CA257090 | Expanding the Druggable Human Genome | 000 | 4 | NIH | 1/20/2025 | -$22,159 |
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