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Implementation of a Provider-Focused Intervention for Maximizing HPV Vaccine Uptake in Young Cancer Survivors receiving Follow-Up Care in Pediatric Oncology Practices: A Cluster-Randomized Trial

Award Number: U01CA246567
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/18/2020
PERIOD OF PERFORMANCE END DATE: 08/31/2025

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Implementation of a Provider-Focused Intervention for Maximizing HPV Vaccine Uptake in Young Cancer Survivors receiving Follow-Up Care in Pediatric Oncology Practices: A Cluster-Randomized Trial - Modified Project Summary/Abstract Section PROJECT SUMMARY/ABSTRACT Childhood cancer survivors are at high risk for developing new cancers (such as cervical and anal cancer) caused by persistent infection with the human papillomavirus (HPV). An effective vaccine exists that can prevent these cancers, but uptake of the HPV vaccine is low among young cancer survivors (fewer than 1 in 4 have received the vaccine). Lack of a healthcare provider recommendation for the HPV vaccine is the most common reason that cancer survivors fail to get the HPV vaccine. Strategies that are most successful in increasing HPV vaccine uptake in the general population focus on improving healthcare provider knowledge about the HPV vaccine, enhancing the skills that healthcare providers need to effectively recommend the vaccine to young people and their parents, and reducing barriers to receiving the vaccine. This proposed research will evaluate the effectiveness and implementation of an evidence-based intervention, adapted for use by healthcare providers in pediatric oncology clinics, to increase the uptake of HPV vaccine among young cancer survivors (9 to 17 years of age and at least one year off-therapy). If the intervention is effective in improving and sustaining increased uptake of the HPV vaccine in young cancer survivors, this study will contribute important information needed to move forward with testing the widespread use of the intervention in pediatric oncology practices. This proposed research addresses improving healthcare delivery and clinical outcomes for cancer survivors through prevention of HPV-associated cancers, which are high-priority research areas for the National Cancer Institute.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = -$3,940 )
2026	2024	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	000	3	12/22/2025	NON-COMPETING CONTINUATION	-$3,940
														Subtotal = -$3,940

Issue Date FY: 2024 ( Subtotal = $577,167 )
2024	2024	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	002	3	7/31/2024	NON-COMPETING CONTINUATION	$577,167
2024	2023	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	001	2	7/30/2024	EXTENSION WITH OR WITHOUT FUNDS	$909
2024	2020	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	000	1	7/30/2024	NEW	-$909
														Subtotal = $577,167

Issue Date FY: 2023 ( Subtotal = $581,623 )
2023	2023	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	000	2	9/14/2023	EXTENSION WITH OR WITHOUT FUNDS	$581,623
														Subtotal = $581,623

Issue Date FY: 2020 ( Subtotal = $1,856,897 )
2020	2020	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	000	1	9/18/2020	NEW	$1,856,897
														Subtotal = $1,856,897

Grand Total All Awards = $3,011,747

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Implementation of a Provider-Focused Intervention for Maximizing HPV Vaccine Uptake in Young Cancer Survivors receiving Follow-Up Care in Pediatric Oncology Practices: A Cluster-Randomized Trial

Award Number: U01CA246567

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/18/2020

PERIOD OF PERFORMANCE END DATE: 08/31/2025

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