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CONGAS: "Caribbean Omics 'N' Genomics for Alzheimer Study"

Award Number: U01AG084514
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 03/01/2026
PERIOD OF PERFORMANCE END DATE: 02/28/2031

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CONGAS: "Caribbean Omics 'N' Genomics for Alzheimer Study" - Genetic studies in the context of Alzheimer Disease (AD) are significantly biased by information coming from the same homogeneous population: Non-Hispanics Whites (NHW). The ADSP Follow-Up Study (FUS) long term goals include to fully reveal the genetic architecture of AD in multiple ethnic groups and examine the AD genome in the context of US-representative population. As of 2016, approximately 13 million people of the total U.S. population, have Caribbean ancestry. The Caribbean Omics & Genomics Alzheimer Study (CONGAS) will contribute to ADSP-FUS mission with 5,000 samples from elderly individuals (>65 yo) across the Caribbean countries and Spain. We will generate blood biomarkers, array data, whole genome sequence, and proteomics for the CONGAS dataset. Participants will be classified according to ATN criteria that will be used as endpoint phenotype in genome, and proteome association analyses, while taking into account admixture and ancestry components. Ultimately, we will identify causal genes and druggable targets and create better prediction models, by using genetics and multi-omic data as tools.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $3,187,492 )
2026	2026	WASHINGTON UNIVERSITY, THE	1 BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Aging Research	001	1	2/25/2026	SUPPLEMENT FOR EXPANSION	$101,153
2026	2026	WASHINGTON UNIVERSITY, THE	1 BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Aging Research	000	1	2/19/2026	NEW	$3,086,339
														Subtotal = $3,187,492

Grand Total All Awards = $3,187,492

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CONGAS: "Caribbean Omics 'N' Genomics for Alzheimer Study"

Award Number: U01AG084514

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 03/01/2026

PERIOD OF PERFORMANCE END DATE: 02/28/2031

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