Contact PD/PI: Powderly, William G. NRSA-Training-001 (075)
J. NRSA Training Core (TL1), 7. Project Summary/Abstract
Washington University School of Medicine has a robust research infrastructure, outstanding faculty mentors,
well-developed clinical and translational research (CTR) training programs, and a large and diverse pool of
excellent pre- and postdoctoral candidates. The objective of the TL1 is to ignite an interest in becoming a CTR
scientist and provide the research experience, coursework, and career development opportunities to achieve
this goal. Over the past 15 years, the TL1 has successfully trained predoctoral MD, PhD, and allied health
doctoral students. For our last competitive renewal, we added postdoctoral trainees interested in
entrepreneurship, technology transfer, and intellectual property development. We now propose to expand our
program to add support for a mentored career development pathway for MD clinical fellows. We describe new
innovative curricula in biomedical informatics, dissemination and implementation (D&I) science, community
engagement, team science, health equity, and online initiatives. We will introduce new mentor training
programs coordinated by the Clinical Research Training Center. We request annual funding for 5 predoctoral
and 7 postdoctoral trainees for 1-2 years.
The overall aims of the TL1 Program are:
Aim 1: Enhance TL1 infrastructure and programs to provide outstanding clinical and translational
research training opportunities for predoctoral and postdoctoral trainees.
Aim 2: Develop competency-based, personalized learning opportunities for diverse trainees focused
on conducting and integrating translational research in populations and across the lifespan.
Aim 3: Engage diverse trainees, community stakeholders in multidisciplinary collaborative clinical and
translational research to accelerate the benefit and impact of translational science.
Aim 4: Provide high–quality comprehensive informatics training.
Aim 5: Perform robust tracking and evaluation of TL1 program, trainees, and alumni, and use these
data to improve the TL1 program.
Trainees will engage in a mentored research experience with one of 74 experienced program faculty, complete
CTR coursework, and engage in career development activities. This award period will focus on expanding
training opportunities and increase recruitment of trainees from diverse backgrounds. The TL1 Program fills a
critical niche at WUSM and our partners through its multidisciplinary focus on clinical and translational
research, and unique emphasis on entrepreneurship, D&I, community engagement, and health equity. We will
also work with the CTSA consortium to share curriculum, training, career development programs, and methods
and tools to continually improve and provide outstanding CTR training in the future.
Project Summary/Abstract Page 1517
Contact PD/PI: Powderly, William G. NRSA-Training-001 (075)
J. NRSA Training Core (TL1)
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