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Collaborative Research Training in Thrombosis and Inflammation

Award Number: T32HL139425
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 08/01/2018
PERIOD OF PERFORMANCE END DATE: 04/30/2029

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Collaborative Research Training in Thrombosis and Inflammation - This is the first competitive renewal of a T32 program to prepare postdoctoral trainees for collaborative research careers in two inter-related topics: thrombosis and inflammation. There is increasing evidence of a direct relationship between thrombosis and inflammation, or thromboinflammation, in numerous human diseases. Inflammation contributes to the pathogenesis of thrombotic disorders such as stroke and coronary artery disease, while thrombosis influences disease severity in inflammatory conditions such as the novel coronavirus 2019 (COVID-19), sepsis, autoimmune diseases, and cancer. Despite the close links between thrombosis and inflammation, to our knowledge, this is the only T32 program in the nation focused specifically on both processes. The Center for Translational Research on Inflammatory Diseases (CTRID) at Michael E. DeBakey VA Medical Center and the Division of Thrombosis Research at Baylor College of Medicine sponsor this collaborative training program with rigorous research opportunities and close mentoring by faculty. The group of 19 faculty mentors includes 9 NIH-funded investigators and 7 VA Merit-funded investigators; 11 of the mentors are physician-scientists and the balance are non-physician scientists. The major strengths of our program include: 1) a cohesive and highly collaborative group of successful mentors with research expertise in relevant topics for our program, including platelets, neutrophils, microvascular thrombosis, stroke, cancer, sepsis, autoimmunity, inflammatory conditions in lung, bone, and infection, among others; 2) a unique combined curriculum with shared didactic and clinically- oriented training for physician and non-physician trainees; and 3) it is based in a thriving research center committed to mentoring, including a weekly seminar series that consists of > 60% speakers with scientific interests aligned with the themes of this T32. In addition to training physician- scientists in biomedical research, PhD scientists will be trained in translational medicine offering a direct interaction with patients with clinical conditions related to the focus of this T32. PhD trainees are paired with physician trainees during these clinical practicums; this collaborative aspect of the program teaches PhD postdoctoral fellows the importance and benefit of conducting research in collaboration with physician-scientists and vice-versa. The program consists of 2-3 years of research training, enriched by didactic courses, an outstanding seminar series and a vibrant scientific environment. Successful renewal of this T32 on thrombosis and inflammation will continue to pave the way for new biological insights and novel ways of prevention and treatment of thrombotic- inflammatory disorders by educating future physician- and non-physician scientists for collaborative research careers in thrombosis and inflammation.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $201,679 )
2025	2025	BAYLOR COLLEGE OF MEDICINE	1 BAYLOR PLZ	HOUSTON	TX	77030	HARRIS	USA	Blood Diseases and Resources Research	003	7	7/23/2025	NON-COMPETING CONTINUATION	$201,679
2025	2024	BAYLOR COLLEGE OF MEDICINE	1 BAYLOR PLZ	HOUSTON	TX	77030	HARRIS	USA	Blood Diseases and Resources Research	002	6	3/11/2025	COMPETING CONTINUATION	$389,037
2025	2022	BAYLOR COLLEGE OF MEDICINE	1 BAYLOR PLZ	HOUSTON	TX	77030	HARRIS	USA	Blood Diseases and Resources Research	001	5	3/11/2025	NON-COMPETING CONTINUATION	-$195,454
2025	2021	BAYLOR COLLEGE OF MEDICINE	1 BAYLOR PLZ	HOUSTON	TX	77030	HARRIS	USA	Blood Diseases and Resources Research	000	4	3/11/2025	NON-COMPETING CONTINUATION	-$193,583
														Subtotal = $201,679

Issue Date FY: 2024 ( Subtotal = $383,389 )
2024	2024	BAYLOR COLLEGE OF MEDICINE	1 BAYLOR PLZ	HOUSTON	TX	77030	HARRIS	USA	Blood Diseases and Resources Research	001	6	4/3/2024	COMPETING CONTINUATION	$359,232
2024	2024	BAYLOR COLLEGE OF MEDICINE	1 BAYLOR PLZ	HOUSTON	TX	77030	HARRIS	USA	Blood Diseases and Resources Research	002	6	8/16/2024	COMPETING CONTINUATION	$24,157
2024	2022	BAYLOR COLLEGE OF MEDICINE	1 BAYLOR PLZ	HOUSTON	TX	77030	HARRIS	USA	Blood Diseases and Resources Research	000	5	3/28/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $383,389

Issue Date FY: 2022 ( Subtotal = $195,454 )
2022	2022	BAYLOR COLLEGE OF MEDICINE	1 BAYLOR PLZ	HOUSTON	TX	77030	HARRIS	USA	Blood Diseases and Resources Research	000	5	7/20/2022	NON-COMPETING CONTINUATION	$195,454
														Subtotal = $195,454

Issue Date FY: 2021 ( Subtotal = $348,925 )
2021	2021	BAYLOR COLLEGE OF MEDICINE	ONE BAYLOR PLAZA	HOUSTON	TX	77030	HARRIS	USA	Blood Diseases and Resources Research	000	4	7/15/2021	NON-COMPETING CONTINUATION	$348,925
														Subtotal = $348,925

Issue Date FY: 2020 ( Subtotal = $344,389 )
2020	2020	BAYLOR COLLEGE OF MEDICINE	ONE BAYLOR PLAZA	HOUSTON	TX	77030	HARRIS	USA	Blood Diseases and Resources Research	000	3	7/17/2020	NON-COMPETING CONTINUATION	$344,389
														Subtotal = $344,389

Issue Date FY: 2019 ( Subtotal = $328,004 )
2019	2019	BAYLOR COLLEGE OF MEDICINE	ONE BAYLOR PLAZA	HOUSTON	TX	77030	HARRIS	USA	Blood Diseases and Resources Research	000	2	7/24/2019	NON-COMPETING CONTINUATION	$328,004
														Subtotal = $328,004

Issue Date FY: 2018 ( Subtotal = $317,294 )
2018	2018	BAYLOR COLLEGE OF MEDICINE	ONE BAYLOR PLAZA	HOUSTON	TX	77030	HARRIS	USA	Blood Diseases and Resources Research	000	1	7/25/2018	NEW	$317,294
														Subtotal = $317,294

Grand Total All Awards = $2,119,134

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Collaborative Research Training in Thrombosis and Inflammation

Award Number: T32HL139425

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 08/01/2018

PERIOD OF PERFORMANCE END DATE: 04/30/2029

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