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Mechanisms of Hypertension and Cardiovascular Diseases

Award Number: T32HL007457
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 07/01/1980
PERIOD OF PERFORMANCE END DATE: 06/30/2026

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Mechanisms of Hypertension and Cardiovascular Diseases - This T32 Postdoctoral Training Program, Mechanisms of Hypertension and Cardiovascular Diseases, has been evolving since its inception in 1979. Additions to the training content to prepare a diverse group of trainees to generate novel basic, clinical and population data to devise innovative strategies to prevent and manage hypertension (HTN) and related cardiovascular disease (CVD) include these key components: addition of 15 Mentors in Training (MiTs) to the T32 Mentoring Network (13 Assistant and 2 Associate Professors); multidisciplinary training exposures via Mini Rotations (trainees learn techniques and concepts not offered within primary Mentor(s) lab; expansion of Interactive Mentoring and Training Modules (Culturally-Relevant Mentoring, LEAD Program Cohorts, Grant/Manuscript Writing, Career Enhancement Workshops, Mental Health & Wellness). Partnerships with the UAB Center for Clinical and Translational Science (CCTS) and the UAB University-Wide Interdisciplinary Research Centers (UWIRCs)-HTN Research Center (HRC) and Center for Women’s Reproductive Health (CWRH) facilitate interdisciplinary research, educational ingenuity and provide substantial resources. This Program offers a spectrum of training in the following Thematic Focus Areas: Basic Science (training in fundamental mechanisms of inflammatory vascular injury and repair and oxidative stress/free radical injury); Translational Science (translation-to-humans, testing basic science discoveries for clinical applicability); Clinical Science (research to improve knowledge and implementation of new therapies); Population Science (analysis of large-scale population-based cohort studies). Of the 41 trainees in the past 15 years (12 female, 29 male, 39% underrepresented minority (URM), 9 MD, 25 PhD, 6 MD/PhD, 1 DrPH), 30 (73%) hold academic positions (Full, Associate or Assistant Professor, Instructor/Researcher), 8 (20%) are pursuing further training and 3 pursued other positions (physician-scientists). These trainees have 161 peer-reviewed publications, 93 as first-author, many in leading journals (Circulation, Circ Res, J Biol Chem, Hypertension, J Clin Invest, PNAS USA, Science). All 6 current trainees are female (50% URM). Our 33 Faculty Mentors (20 male, 13 female, 24 Professors, 6 Associate Professors, 3 Assistant Professors, 42% URM) from 3 Schools, 9 Departments and 7 Divisions have robust and well funded research programs. Nearly $100K in institutional support is committed to the Program. Trainees will spend 2-3 years in investigation, coursework, presentation/publication of research and career enhancement. Importantly, this is the only postdoctoral training program in Alabama, a state with a high rate of HTN and related CVD, that provides highly integrated “bench to bedside” training in basic, clinical, population and implementation research in HTN and CVD. Our overall goal is to address a shortage of scientists trained to use cutting edge approaches to problems related to hypertension and CVD, a leading cause of death and disability in the US.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $367,128 )
2024	2024	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	001	44	8/1/2024	NON-COMPETING CONTINUATION	$367,128
2024	2023	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	000	43	11/9/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $367,128

Issue Date FY: 2023 ( Subtotal = $46,893 )
2023	2023	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	000	43	7/17/2023	NON-COMPETING CONTINUATION	$46,893
														Subtotal = $46,893

Issue Date FY: 2022 ( Subtotal = $499,594 )
2022	2022	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	003	42	8/5/2022	NON-COMPETING CONTINUATION	$499,594
2022	2021	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	002	41	2/23/2022	COMPETING CONTINUATION	$464,578
2022	2020	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	001	40	2/23/2022	NON-COMPETING CONTINUATION	-$245,280
2022	2019	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	000	39	2/23/2022	NON-COMPETING CONTINUATION	-$219,298
														Subtotal = $499,594

Issue Date FY: 2021 ( Subtotal = $476,300 )
2021	2021	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	000	41	6/30/2021	COMPETING CONTINUATION	$476,300
														Subtotal = $476,300

Issue Date FY: 2020 ( Subtotal = $245,280 )
2020	2020	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	000	40	7/18/2020	NON-COMPETING CONTINUATION	$245,280
														Subtotal = $245,280

Issue Date FY: 2019 ( Subtotal = $316,163 )
2019	2019	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	000	39	6/28/2019	NON-COMPETING CONTINUATION	$316,163
														Subtotal = $316,163

Issue Date FY: 2018 ( Subtotal = $424,497 )
2018	2018	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	000	38	6/21/2018	NON-COMPETING CONTINUATION	$424,497
														Subtotal = $424,497

Issue Date FY: 2017 ( Subtotal = $427,984 )
2017	2017	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	007	36	5/8/2017	SUPPLEMENT FOR EXPANSION	$6,687
2017	2017	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	009	36	6/20/2017	SUPPLEMENT FOR EXPANSION	$3,701
2017	2017	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	006	36	1/30/2017	SUPPLEMENT FOR EXPANSION	$6,383
2017	2017	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	004	35	12/23/2016	SUPPLEMENT FOR EXPANSION	$0
2017	2017	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	003	35	12/22/2016	SUPPLEMENT FOR EXPANSION	$6,383
2017	2017	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	008	37	6/9/2017	NON-COMPETING CONTINUATION	$411,213
2017	2017	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	005	35	1/30/2017	SUPPLEMENT FOR EXPANSION	-$6,383
2017	2016	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	002	36	10/27/2016	COMPETING CONTINUATION	$322,843
2017	2015	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	001	35	10/27/2016	NON-COMPETING CONTINUATION	-$229,826
2017	2014	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	000	34	10/27/2016	NON-COMPETING CONTINUATION	-$93,017
														Subtotal = $427,984

Issue Date FY: 2016 ( Subtotal = $399,782 )
2016	2016	UNIVERSITY OF ALABAMA AT BIRMINGHAM	1530 3rd Avenue South, AB 1170	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	000	36	4/16/2016	COMPETING CONTINUATION	$399,782
														Subtotal = $399,782

Issue Date FY: 2015 ( Subtotal = $229,826 )
2015	2015	UNIVERSITY OF ALABAMA AT BIRMINGHAM	1530 3rd Avenue South, AB 1170	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	000	35	6/29/2015	NON-COMPETING CONTINUATION	$229,826
														Subtotal = $229,826

Issue Date FY: 2014 ( Subtotal = $301,372 )
2014	2014	UNIVERSITY OF ALABAMA AT BIRMINGHAM	1530 3rd Avenue South, AB 1170	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	000	34	6/6/2014	NON-COMPETING CONTINUATION	$301,372
														Subtotal = $301,372

Issue Date FY: 2013 ( Subtotal = $365,771 )
2013	2013	UNIVERSITY OF ALABAMA AT BIRMINGHAM	UAB STATION, CBB 990	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	000	33	7/8/2013	NON-COMPETING CONTINUATION	$365,771
														Subtotal = $365,771

Issue Date FY: 2012 ( Subtotal = $365,771 )
2012	2012	UNIVERSITY OF ALABAMA AT BIRMINGHAM	UAB STATION, CBB 990	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	000	32	6/20/2012	NON-COMPETING CONTINUATION	$365,771
														Subtotal = $365,771

Issue Date FY: 2011 ( Subtotal = $353,245 )
2011	2011	UNIVERSITY OF ALABAMA AT BIRMINGHAM	UAB STATION, CBB 990	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	000	31	7/1/2011	COMPETING CONTINUATION	$353,245
														Subtotal = $353,245

Issue Date FY: 2010 ( Subtotal = $164,173 )
2010	2010	UNIVERSITY OF ALABAMA AT BIRMINGHAM	UAB STATION, CBB 990	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	000	30	6/3/2010	NON-COMPETING CONTINUATION	$164,173
														Subtotal = $164,173

Issue Date FY: 2009 ( Subtotal = $348,077 )
2009	2009	UNIVERSITY OF ALABAMA AT BIRMINGHAM	UAB STATION, CBB 990	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	000	29	6/11/2009	NON-COMPETING CONTINUATION	$348,077
														Subtotal = $348,077

Issue Date FY: 2008 ( Subtotal = $345,239 )
2008	2008	UNIVERSITY OF ALABAMA AT BIRMINGHAM	UAB STATION, CBB 990	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	000	28	4/25/2008	NON-COMPETING CONTINUATION	$345,239
														Subtotal = $345,239

Issue Date FY: 2007 ( Subtotal = $345,239 )
2007	2007	UNIVERSITY OF ALABAMA AT BIRMINGHAM	UAB STATION, CBB 990	BIRMINGHAM	AL	35294	JEFFERSON	USA	Cardiovascular Diseases Research	000	27	5/11/2007	NON-COMPETING CONTINUATION	$345,239
														Subtotal = $345,239

Issue Date FY: 2006 ( Subtotal = $292,489 ) (Continued on the next page)
Grand Total All Awards = $7,953,195

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Mechanisms of Hypertension and Cardiovascular Diseases

Award Number: T32HL007457

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 07/01/1980

PERIOD OF PERFORMANCE END DATE: 06/30/2026

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