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Integrative Pharmacological Sciences Training Program (IPSTP)

Award Number: T32GM142521
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 07/01/2021
PERIOD OF PERFORMANCE END DATE: 06/30/2026

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Integrative Pharmacological Sciences Training Program (IPSTP) - - 5T32GM142521-04 The Integrative Pharmacological Sciences Training Program (IPSTP) at Michigan State University is designed to support 2nd and 3rd year Ph.D. students pursuing dissertation research projects in the pharmacological sciences. Trainees and training faculty are drawn from 7 departmental Ph.D. programs (Biochemistry & Molecular Biology, Chemistry, Chemical Engineering and Materials Science, Microbiology, Genetics and Immunology, Neuroscience, Pharmacology & Toxicology, and Molecular, Cellular and Integrative Physiology). The IPSTP will provide students with enhanced training in the fields of in vivo pharmacology, drug discovery, and big data. The research expertise of IPSTP training faculty is clustered into three overlapping themes: 1) the intersection of molecular mechanisms of disease with novel therapeutic design; 2) integration of endocrine and metabolic derangements with cancer and cardiovascular processes; and, 3) application of systems biology and bioinformatics to understand drug mechanisms and disease. Funds are requested to support 8 students (4 students entering the program per year). Dr. Dorrance and Dr. Leinninger will serve as co-directors, and Dr. Luyendyk will serve as associate director. The Directors will be assisted by an Executive Committee composed of representatives from the programs and 2 student representatives. The program is also guided by an External Advisory Committee of experts from Pharmacology Ph.D. programs and the pharmaceutical industry. There are 8 core elements to the training plan: 1) a research project that leads to a Ph.D. dissertation and a contribution to knowledge in the pharmacological sciences; 2) three week-long intensive boot camps in drug discovery, in vivo pharmacology, and computational chemistry/big data; 3) a three-course curriculum in pharmacology and biostatistics, 4) training in scientific rigor and reproducibility 5) a Professional Development Forum; 6) participation in an annual program retreat; 7) a monthly journal club and chalk talk program, and 8) an individualized development plan program. Students will be expected to participate in the last four elements both during their direct T32 support period and for subsequent years until graduation. Trainees are also required to attend the Responsible Conduct of Research (RCR) workshop series provided by the Graduate School and program-specific RCR activities. Supplemental activities available to trainees include: 1) teaching opportunities; 2) participation in the NIH-funded MSU BEST program, and 3) field-trips to regional sites for non-academic careers. The IPSTP has developed a comprehensive plan to recruit highly qualified students and support their training so that they will be competitive for the biomedical workforce. We have also developed comprehensive plans for program and student evaluation. Mentor training will also be required for all IPSTP program faculty and the quality of the mentoring received by the students will be assessed. The IPSTP will provide trainees with excellent research and professional training and will prepare them for research careers in academia, industry and government.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $309,144 )
2025	2025	MICHIGAN STATE UNIVERSITY	426 AUDITORIUM RD RM 2	EAST LANSING	MI	48824	INGHAM	USA	Biomedical Research and Research Training	000	5	6/6/2025	NON-COMPETING CONTINUATION	$309,144
														Subtotal = $309,144

Issue Date FY: 2024 ( Subtotal = $423,319 )
2024	2024	MICHIGAN STATE UNIVERSITY	426 AUDITORIUM RD RM 2	EAST LANSING	MI	48824	INGHAM	USA	Biomedical Research and Research Training	001	4	6/13/2024	NON-COMPETING CONTINUATION	$423,319
2024	2023	MICHIGAN STATE UNIVERSITY	426 AUDITORIUM RD RM 2	EAST LANSING	MI	48824	INGHAM	USA	Biomedical Research and Research Training	000	3	11/16/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $423,319

Issue Date FY: 2023 ( Subtotal = $408,260 )
2023	2023	MICHIGAN STATE UNIVERSITY	426 AUDITORIUM RD RM 2	EAST LANSING	MI	48824	INGHAM	USA	Biomedical Research and Research Training	000	3	5/12/2023	NON-COMPETING CONTINUATION	$408,260
														Subtotal = $408,260

Issue Date FY: 2022 ( Subtotal = $400,121 )
2022	2022	MICHIGAN STATE UNIVERSITY	426 AUDITORIUM RD RM 2	EAST LANSING	MI	48824	INGHAM	USA	Biomedical Research and Research Training	001	2	5/24/2022	NON-COMPETING CONTINUATION	-$9
2022	2022	MICHIGAN STATE UNIVERSITY	426 AUDITORIUM RD RM 2	EAST LANSING	MI	48824	INGHAM	USA	Biomedical Research and Research Training	000	2	5/4/2022	NON-COMPETING CONTINUATION	$400,130
														Subtotal = $400,121

Issue Date FY: 2021 ( Subtotal = $373,935 )
2021	2021	MICHIGAN STATE UNIVERSITY	426 AUDITORIUM RD RM 2	EAST LANSING	MI	48824	INGHAM	USA	Biomedical Research and Research Training	000	1	6/8/2021	NEW	$373,935
														Subtotal = $373,935

Grand Total All Awards = $1,914,779

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Integrative Pharmacological Sciences Training Program (IPSTP)

Award Number: T32GM142521

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 07/01/2021

PERIOD OF PERFORMANCE END DATE: 06/30/2026

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