Wednesday, July 30, 2025 7/30/2025

Harvard Chemical Biology PhD Program

Award Number: T32GM139775
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 07/01/2022
PERIOD OF PERFORMANCE END DATE: 06/30/2027

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Harvard Chemical Biology PhD Program - Project Summary This application requests support for the PhD Program in Chemical Biology at Harvard University. This profoundly interdisciplinary program trains highly talented students to carry out independent research at the forefront of chemical biology, addressing biological and medical problems using concepts and experimental approaches drawn from many areas of chemistry and biology and developing novel, broadly relevant technologies. The training program offers an extraordinary range of training opportunities in chemical biology. Faculty members at Harvard’s Cambridge campus offer world-class expertise in the disciplines spanning organic chemistry and the molecular life sciences, while faculty members at the Harvard Medical School (HMS) offer outstanding strengths at the interface between the molecular life sciences and biomedical problems. In addition, the Broad Institute of Harvard and MIT is a leader in technology development relevant to genomics, therapeutic discovery and medicine. The Program thus represents a mechanism to transfer concepts and technologies from chemistry to biology, medicine and genomics and vice versa. Students enter the program from a variety of backgrounds. Required coursework in the first year, provides core training in kinetics, chemical structure and reactivity as well as the application of thermodynamic concepts in the context of biology. Students are also required to take courses focused on reproducible research, statistics, and record-keeping as well as teamwork, communication and ethics. A unifying theme of first year coursework and discussions is the role of chemical tools and approaches in dissecting biological pathways. Students also take elective courses in synthetic organic chemistry, microbiology, cell biology, structural biology, genetics and genomics, proteomics, metabolomics and systems biology. They are exposed to an unusual range of technologies and concepts in chemical biology through coursework, interactions with faculty and other students, and Program events such as the Program retreat and Student Data Club. In addition, they develop communication skills, gain teaching experience and receive training in responsible conduct of research. Trainees are also supported in exploring a wide range of careers inside and outside academia. The previous grant supported 10 trainees and we request support for 10 trainees in this new proposal. The Program aims to attract a diverse community of talented students and give them intensive, personalized support as they develop an interdisciplinary understanding of biological questions and chemical concepts and approaches, and gain independence in posing and answering such questions. The program pays particular attention to rigor and reproducibility, training students in the physicochemical basis of the measurements they make and in appropriate techniques, and common pitfalls, in scientific analysis. Training for communication across disciplines and to the lay public is foundational for the Program and is emphasized throughout each student’s career. Communication is also foundational for multiple types of future careers.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $531,450 )
2025	2025	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	1033 MASSACHUSETTS AVE STE 3	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Biomedical Research and Research Training	000	4	7/8/2025	NON-COMPETING CONTINUATION	$531,450
														Subtotal = $531,450

Issue Date FY: 2024 ( Subtotal = $549,359 )
2024	2024	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	1033 MASSACHUSETTS AVE STE 3	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Biomedical Research and Research Training	002	3	7/2/2024	NON-COMPETING CONTINUATION	$18,824
2024	2024	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	1033 MASSACHUSETTS AVE STE 3	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Biomedical Research and Research Training	001	3	3/7/2024	NON-COMPETING CONTINUATION	$530,535
2024	2023	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	1033 MASSACHUSETTS AVE STE 3	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Biomedical Research and Research Training	000	2	12/6/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $549,359

Issue Date FY: 2023 ( Subtotal = $530,535 )
2023	2023	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	1033 MASSACHUSETTS AVE 5TH FL	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Biomedical Research and Research Training	000	2	5/23/2023	NON-COMPETING CONTINUATION	$530,535
														Subtotal = $530,535

Issue Date FY: 2022 ( Subtotal = $520,362 )
2022	2022	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	1033 MASSACHUSETTS AVE 5TH FL	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Biomedical Research and Research Training	001	1	8/3/2022	NEW	-$10
2022	2022	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	1033 MASSACHUSETTS AVE 5TH FL	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Biomedical Research and Research Training	000	1	5/5/2022	NEW	$520,372
														Subtotal = $520,362

Grand Total All Awards = $2,131,706

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Harvard Chemical Biology PhD Program

Award Number: T32GM139775

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 07/01/2022

PERIOD OF PERFORMANCE END DATE: 06/30/2027

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