Saturday, September 30, 2023 9/30/2023

TRAINING IN SIGNALING AND CELLULAR REGULATION

Award Number: T32GM008759
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

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DESCRIPTION (provided by applicant): The goal of this training grant proposal is to prepare gifted predoctoral trainees for productive research careers in the field of signaling and cellular regulation. The training faculty consists of an outstanding, internationally recognized group of investigators in the Depts. of Chemistry and Biochemistry; Molecular, Cellular, Developmental Biology; Applied Mathematics; and Chemical and Biological Engineering, who study basic cell regulatory mechanisms through discovery and characterization of key components in signaling pathways, transfer of biological information through protein conformational changes and posttranslational modifications, mathematical modeling of complex biological pathways, and formulation of new therapeutic strategies for human diseases. The program provides students with rigorous training in experimental design, scientific technique, and data evaluation, exposure to a wide range of scientific disciplines, training in classroom teaching, opportunities for scientific presentation, and training in standards for professional conduct. In Year 1, students take coursework and teaching duties in their home departments, and carry out laboratory rotations. At the end of Year 1, students choose a thesis advisor and elect to join this training program. In Year 2, students begin research and take elective coursework tailored to this program. Written and oral qualifying exams including the defense of a dissertation research proposal are required to advance to Ph.D. candidacy. In Years 3 and beyond, students obtain high caliber research training through the thesis project, with progress monitored yearly until graduation. Students add to their breadth and knowledge by participating in program supergroups, journal clubs, and seminars, and by presenting their work before large audiences. Students complete the program by defending a doctoral dissertation and receive a Ph.D. degree in Biochemistry or MCDB. Most students finish within 5-6 years of matriculation, and go on to postdoctoral training and careers in academia, research institutes, or pharmaceutical/biotechnology companies.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2022 ( Subtotal = -$3,777 )
2022	2020	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST STE 481 572 UCB	BOULDER	CO	80309	BOULDER	USA	Biomedical Research and Research Training	001	20	12/7/2021	NON-COMPETING CONTINUATION	-$3,777
2022	2009	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST STE 481 572 UCB	BOULDER	CO	80309	BOULDER	USA	Trans-NIH Recovery Act Research Support	000	9	12/7/2021	SUPPLEMENT FOR EXPANSION	$3,777
2022	2009	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST STE 481 572 UCB	BOULDER	CO	80309	BOULDER	USA	Trans-NIH Recovery Act Research Support	002	9	1/12/2022	SUPPLEMENT FOR EXPANSION	-$3,777


Issue Date FY: 2020 ( Subtotal = $387,612 )
2020	2020	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST STE 481 572 UCB	BOULDER	CO	80309	BOULDER	USA	Biomedical Research and Research Training	000	20	6/1/2020	NON-COMPETING CONTINUATION	$387,612


Issue Date FY: 2019 ( Subtotal = $390,071 )
2019	2019	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST STE 481 572 UCB	BOULDER	CO	80309	BOULDER	USA	Biomedical Research and Research Training	000	19	6/18/2019	NON-COMPETING CONTINUATION	$390,643
2019	2015	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST STE 481 572 UCB	BOULDER	CO	80309	BOULDER	USA	Biomedical Research and Research Training	001	15	9/24/2019	NON-COMPETING CONTINUATION	-$572


Issue Date FY: 2018 ( Subtotal = $385,329 )
2018	2018	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST., RM 479 572 UCB	BOULDER	CO	80303	BOULDER	USA	Biomedical Research and Research Training	000	18	5/21/2018	NON-COMPETING CONTINUATION	$385,329


Issue Date FY: 2017 ( Subtotal = $380,149 )
2017	2017	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST., RM 479 572 UCB	BOULDER	CO	80303	BOULDER	USA	Biomedical Research and Research Training	002	17	5/23/2017	NON-COMPETING CONTINUATION	$375,095
2017	2017	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST., RM 479 572 UCB	BOULDER	CO	80303	BOULDER	USA	Biomedical Research and Research Training	003	17	7/21/2017	NON-COMPETING CONTINUATION	$5,054
2017	2016	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST., RM 479 572 UCB	BOULDER	CO	80303	BOULDER	USA	Biomedical Research and Research Training	001	16	2/16/2017	COMPETING CONTINUATION	$3,101
2017	2015	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST., RM 479 572 UCB	BOULDER	CO	80303	BOULDER	USA	Biomedical Research and Research Training	000	15	2/16/2017	NON-COMPETING CONTINUATION	-$3,101


Issue Date FY: 2016 ( Subtotal = $375,095 )
2016	2016	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Biomedical Research and Research Training	000	16	6/28/2016	COMPETING CONTINUATION	$375,095


Issue Date FY: 2015 ( Subtotal = $309,788 )
2015	2015	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Biomedical Research and Research Training	000	15	5/15/2015	NON-COMPETING CONTINUATION	$309,788


Issue Date FY: 2014 ( Subtotal = $309,592 )
2014	2014	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Biomedical Research and Research Training	000	14	7/1/2014	NON-COMPETING CONTINUATION	$309,592


Issue Date FY: 2013 ( Subtotal = $305,276 )
2013	2013	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Biomedical Research and Research Training	000	13	7/2/2013	NON-COMPETING CONTINUATION	$305,276


Issue Date FY: 2012 ( Subtotal = $271,356 )
2012	2012	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Biomedical Research and Research Training	000	12	7/11/2012	NON-COMPETING CONTINUATION	$271,356


Issue Date FY: 2011 ( Subtotal = $267,624 )
2011	2011	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Biomedical Research and Research Training	000	11	6/17/2011	COMPETING CONTINUATION	$267,624


Issue Date FY: 2010 ( Subtotal = $257,674 )
2010	2010	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Biomedical Research and Research Training	000	10	6/30/2010	NON-COMPETING CONTINUATION	$257,674


Issue Date FY: 2009 ( Subtotal = $386,977 )
2009	2009	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Trans-NIH Recovery Act Research Support	002	9	8/7/2009	SUPPLEMENT FOR EXPANSION	$128,992
2009	2009	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Biomedical Research and Research Training	000	9	6/18/2009	NON-COMPETING CONTINUATION	$257,985
2009	2009	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Biomedical Research and Research Training	001	9	8/7/2009	NON-COMPETING CONTINUATION	$0


Issue Date FY: 2008 ( Subtotal = $256,222 )
2008	2008	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Biomedical Research and Research Training	000	8	6/18/2008	NON-COMPETING CONTINUATION	$256,222


Issue Date FY: 2007 ( Subtotal = $256,222 )
2007	2007	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Biomedical Research and Research Training	000	7	6/13/2007	NON-COMPETING CONTINUATION	$256,222


Issue Date FY: 2006 ( Subtotal = $236,518 )
2006	2006	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Biomedical Research and Research Training	000	6	6/30/2006	COMPETING CONTINUATION	$236,518


Issue Date FY: 2004 ( Subtotal = $236,009 )
2004	2004	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Biomedical Research and Research Training	000	5	5/28/2004	NON-COMPETING CONTINUATION	$236,009


Issue Date FY: 2003 ( Subtotal = $229,572 )
2003	2003	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Cell Biology and Biophysics Research	000	4	6/16/2003	NON-COMPETING CONTINUATION	$229,572


Issue Date FY: 2002 ( Subtotal = $213,916 )
2002	2002	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Cell Biology and Biophysics Research	000	3	6/28/2002	NON-COMPETING CONTINUATION	$213,916


Issue Date FY: 2001 ( Subtotal = $197,880 )
2001	2001	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Cell Biology and Biophysics Research	000	2	6/11/2001	NON-COMPETING CONTINUATION	$197,880


Issue Date FY: 2000 ( Subtotal = $139,079 )
2000	2000	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Cell Biology and Biophysics Research	000	1	6/16/2000	NEW	$139,079


Grand Total All Awards = $5,788,184

Sum of Action Amount is $5,788,184;

Grand Total = $5,788,184

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TRAINING IN SIGNALING AND CELLULAR REGULATION

Award Number: T32GM008759

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

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