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Clinical Pharmacology Training Program

Award Number: T32GM008562
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 07/01/1995
PERIOD OF PERFORMANCE END DATE: 06/30/2030

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Clinical Pharmacology Training Program - Enter the text here that is the new abstract information for your application. This section must be no longer than 30 lines of text. This is a proposal to continue the support of our collaborative postdoctoral training program in adult, pediatric and maternal-fetal clinical pharmacology at Thomas Jefferson University (TJU) and the Children’s Hospital of Philadelphia (CHOP). The mission of our joint program is to train the next generation of drug development scientists to ensure innovation in therapeutics that transforms disease management. To accomplish this, we seek to identify basic, translational, and clinical investigators with an interest in adult, pediatric and/or maternal-fetal therapeutics, and provide a curriculum that prepares trainees for research careers in academia, industry, or regulatory agencies. The program is designed for postdoctoral fellows, including MDs, MD-PhDs, PharmDs, and PhDs, leveraging the exceptional research environment of our two institutions to support training that addresses workforce needs in the field. Our 2-year program pairs a well-established curriculum of didactic coursework, conferences, and rotations with mentored research in mechanism-based discovery, drug development, pharmacometrics, experimental medicine, and drug safety; the majority of fellows’ time is focused on hypothesis-driven research. The breadth of pediatric and adult clinical pharmacology is delivered using a framework built on the TJU Training Program in Human Investigation. Courses cover clinical pharmacology, clinical trials design, biostatistics, pharmacoepidemiology, pharmacometrics, regulatory science, research ethics, data management, leadership, grant writing and presentation skills. Advanced training in academic and industrial pharmacometrics is an elective offering. Conferences include journal club in human therapeutics, research ethics, and seminars in human therapeutics. Rotations provide experience in the critical analysis of the scientific literature on the editorial board of the Annals of Internal Medicine; critical review of human subjects research on our institutional review boards (IRBs); clinical trial execution in the TJU Clinical Research Unit or within the inpatient setting at CHOP; or analytic method development to support trainee pharmacokinetic studies. Fellows customize their education by selecting electives congruent with career aspirations, including off-site rotations at industrial drug development partners and/or regulatory agencies such as the Food and Drug Administration (FDA). Opportunities in pediatric and adult experimental therapeutics are offered by 55 preceptors representing 6 broad areas of distinction, including cancer biology, cardiopulmonary medicine, neurosciences, immunology and infectious diseases, neonatology and maternal therapeutics, and pediatric therapeutics. Preceptors are selected based on their productive research programs related to therapeutics, training success, and commitment to training. This program will continue to build upon an exemplary record of recruiting trainees who have been uniformly successful in academia, the biopharmaceutical industry, and the FDA.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $592,492 )
2025	2025	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST STE 1	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	001	31	6/27/2025	COMPETING CONTINUATION	$592,492
2025	2024	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST STE 1	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	000	30	10/29/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $592,492

Issue Date FY: 2024 ( Subtotal = $888,184 )
2024	2024	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST STE 1	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	001	30	8/20/2024	NON-COMPETING CONTINUATION	$888,184
2024	2023	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	000	29	4/8/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $888,184

Issue Date FY: 2023 ( Subtotal = $835,075 )
2023	2023	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	002	29	8/21/2023	NON-COMPETING CONTINUATION	$835,075
2023	2020	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	001	26	4/11/2023	COMPETING CONTINUATION	-$380,064
2023	2019	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	000	25	4/11/2023	NON-COMPETING CONTINUATION	$380,064
														Subtotal = $835,075

Issue Date FY: 2022 ( Subtotal = $815,600 )
2022	2022	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST STE 1	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	004	28	9/2/2022	NON-COMPETING CONTINUATION	$815,600
2022	2021	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST STE 1	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	003	27	10/25/2021	NON-COMPETING CONTINUATION	$0
2022	2020	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST STE 1	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	002	26	10/17/2021	COMPETING CONTINUATION	$594,671
2022	2019	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST STE 1	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	001	25	10/17/2021	NON-COMPETING CONTINUATION	-$322,528
2022	2018	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST STE 1	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	000	24	10/17/2021	NON-COMPETING CONTINUATION	-$272,143
														Subtotal = $815,600

Issue Date FY: 2021 ( Subtotal = $783,435 )
2021	2021	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST STE 1	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	000	27	7/2/2021	NON-COMPETING CONTINUATION	$783,435
														Subtotal = $783,435

Issue Date FY: 2020 ( Subtotal = $774,341 )
2020	2020	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST STE 1	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	001	26	6/30/2020	COMPETING CONTINUATION	$774,341
2020	2019	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST STE 1	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	000	25	6/30/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $774,341

Issue Date FY: 2019 ( Subtotal = $322,528 )
2019	2019	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST STE 1	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	001	25	6/12/2019	NON-COMPETING CONTINUATION	$322,528
2019	2018	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST STE 1	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	000	24	10/24/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $322,528

Issue Date FY: 2018 ( Subtotal = $636,774 )
2018	2018	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST STE 1	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	000	24	6/22/2018	NON-COMPETING CONTINUATION	$636,774
														Subtotal = $636,774

Issue Date FY: 2017 ( Subtotal = $519,705 )
2017	2017	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST STE 1	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	001	23	7/11/2017	NON-COMPETING CONTINUATION	$77,843
2017	2017	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST STE 1	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	000	23	5/17/2017	NON-COMPETING CONTINUATION	$441,862
														Subtotal = $519,705

Issue Date FY: 2016 ( Subtotal = $442,419 )
2016	2016	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	000	22	6/17/2016	NON-COMPETING CONTINUATION	$442,419
														Subtotal = $442,419

Issue Date FY: 2015 ( Subtotal = $139,608 )
2015	2015	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	000	21	5/15/2015	COMPETING CONTINUATION	$139,608
2015	2015	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	001	21	6/5/2015	COMPETING CONTINUATION	$0
														Subtotal = $139,608

Issue Date FY: 2014 ( Subtotal = $73,213 )
2014	2014	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	000	20	7/21/2014	NON-COMPETING CONTINUATION	$73,213
														Subtotal = $73,213

Issue Date FY: 2013 ( Subtotal = $288,130 )
2013	2013	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	000	19	6/14/2013	NON-COMPETING CONTINUATION	$288,130
														Subtotal = $288,130

Issue Date FY: 2012 ( Subtotal = $275,072 )
2012	2012	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	001	18	9/7/2012	NON-COMPETING CONTINUATION	$67,392
2012	2012	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	000	18	6/28/2012	NON-COMPETING CONTINUATION	$207,680
														Subtotal = $275,072

Issue Date FY: 2011 ( Subtotal = $261,510 )
2011	2011	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	000	17	6/8/2011	NON-COMPETING CONTINUATION	$261,510
														Subtotal = $261,510

Issue Date FY: 2010 ( Subtotal = $263,752 )
2010	2010	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	001	16	8/2/2010	COMPETING CONTINUATION	$61,366
2010	2010	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	000	16	6/28/2010	COMPETING CONTINUATION	$202,386
														Subtotal = $263,752

Issue Date FY: 2009 ( Subtotal = $121,998 )
2009	2009	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	001	15	7/13/2009	NON-COMPETING CONTINUATION	$121,998
2009	2008	THOMAS JEFFERSON UNIVERSITY	1020 WALNUT ST	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Biomedical Research and Research Training	000	14	6/9/2009	NON-COMPETING CONTINUATION	$0
														Subtotal = $121,998

Issue Date FY: 2008 ( Subtotal = $224,355 ) (Continued on the next page)
Grand Total All Awards = $9,456,523

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Clinical Pharmacology Training Program

Award Number: T32GM008562

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 07/01/1995

PERIOD OF PERFORMANCE END DATE: 06/30/2030

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