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Pre-doctoral Training in Systems Toxicology

Award Number: T32ES032920
ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 07/01/2022
PERIOD OF PERFORMANCE END DATE: 06/30/2027

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Pre-doctoral Training in Systems Toxicology - Inhalation exposures to a large variety of airborne toxicants are an ever-present, rising and ubiquitous public health threat in our environments whether it be outdoor air pollution, industrial processes, or indoor domestic or occupational toxicants. Inhalation exposures are widely associated with adverse health outcomes in major physiological systems such as: pulmonary (asbestosis, black lung, silicosis); cardiovascular (ischemia, infarction); neural (stroke, behavior), immune (inflammation); and endocrine/reproductive (disruption, developmental origins of health and disease). The whole of West Virginia is part of Appalachia, wherein significant health disparities such as cardiovascular/cerebrovascular disease, obesity, diabetes, metabolic syndrome, depression and addiction are disproportionately high. Further, poor socioeconomic status, and geography (thermal inversions) trap communities in the immediate proximity of mountain-top mining (surface mining) and hydraulic fracturing (“fracking”) operations that produce tremendous amounts of industrial air pollution. An immediate demand exists to train the next generation of scientists able to accurately assess the complex interplay among these toxicological risks, and ultimately improve public health in West Virginia and the nation. The Predoctoral Training in Systems Toxicology Program will formalize and standardize our already strong training programs in the biomedical sciences and focus on inhalation toxicology research. Several innovative aspects of this training program are semester-long didactic courses in “Toxicology” and the “Inhalation & Aerosol Sciences”, a unique “Environmental Immersion” in community outreach/engagement via air sampling downwind of mountaintop/surface mines and fracking platforms, the “Paracelsus Society” colloquium and journal club, an Associate Scholars Program and leadership training. This rigorous training program will select the best doctoral students from the participating Biomedical Sciences Ph.D. and Clinical & Translational Sciences Ph.D. training programs at the West Virginia University (WVU) Health Sciences Center (WVU HSC) and Engineering and will prepare them with the skills, knowledge and acumen needed for a successful career in the various field of toxicology. It is projected that up to 40 trainees will be enrolled in this program during the funding period. The specific training for each mentee will be tailored based on their annually updated Individualized Development Plan (IDP), and a “Career Options” Program will help prepare them for their chosen career in the toxicology field. Program training is expected to last 2-to-3 years. This pre-doctoral training program will create a new generation of young scholars who can directly address the need for innovative toxicology research for the citizens of West Virginia, Appalachia, and the nation.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $280,105 )
2026	2026	WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION	886 CHESTNUT RIDGE ROAD	MORGANTOWN	WV	26505	MONONGALIA	USA	Environmental Health	000	5	7/15/2026	NON-COMPETING CONTINUATION	$280,105
														Subtotal = $280,105

Issue Date FY: 2025 ( Subtotal = $323,430 )
2025	2025	WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION	886 CHESTNUT RIDGE ROAD	MORGANTOWN	WV	26505	MONONGALIA	USA	Environmental Health	000	4	7/9/2025	NON-COMPETING CONTINUATION	$323,430
														Subtotal = $323,430

Issue Date FY: 2024 ( Subtotal = $323,196 )
2024	2024	WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION	886 CHESTNUT RIDGE ROAD	MORGANTOWN	WV	26505	MONONGALIA	USA	Environmental Health	000	3	6/4/2024	NON-COMPETING CONTINUATION	$323,196
														Subtotal = $323,196

Issue Date FY: 2023 ( Subtotal = $161,321 )
2023	2023	WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION	886 CHESTNUT RIDGE ROAD	MORGANTOWN	WV	26505	MONONGALIA	USA	Environmental Health	000	2	4/27/2023	NON-COMPETING CONTINUATION	$161,321
														Subtotal = $161,321

Issue Date FY: 2022 ( Subtotal = $158,268 )
2022	2022	WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION	886 CHESTNUT RIDGE	MORGANTOWN	WV	26506	MONONGALIA	USA	Environmental Health	000	1	6/2/2022	NEW	$158,268
														Subtotal = $158,268

Grand Total All Awards = $1,246,320

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Pre-doctoral Training in Systems Toxicology

Award Number: T32ES032920

ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 07/01/2022

PERIOD OF PERFORMANCE END DATE: 06/30/2027

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