ABSTRACT
We propose renewal of the University of Alabama at Birmingham (UAB) Cancer Prevention and Control Training
Program T32 training grant. Our training program is the only one in the Deep South (Louisiana, Mississippi,
Alabama, Georgia, South Carolina). The Deep South has high cancer mortality rates and an increased
prevalence of multiple chronic diseases, including obesity and diabetes, which are risk factors for cancer that
disproportionately affect African Americans. Our Specific Aims are to: (1) recruit well-qualified pre- and
postdoctoral Fellows, especially those from underrepresented minority (URM) backgrounds, who aspire to
become independent cancer prevention and control researchers and who will address the complex health care
challenges in the Deep South; (2) train pre- and postdoctoral Fellows in cancer prevention and control research,
transdisciplinary research methods, and research ethics while developing their professional, relational, and
leadership skills; (3) leverage UAB’s rich training environment to provide collaboration opportunities within the
O’Neal Comprehensive Cancer Center Cancer Control and Population Science Program; and (4) evaluate and
enhance how well the training program meets the needs of our Fellows and expands the pipeline of future cancer
prevention and control scientists. Our training program has three components: mentoring, experiential
learning, and coursework. Fellows will receive individualized support from a dual-mentor team selected from
our pool of 49 faculty mentors, selected for their prior successful mentoring experience and strong research track
records. Experiential learning activities will center primarily on immersion in the laboratories of Fellows’
primary mentors. All Fellows will write a grant application and design and conduct their own research
study, leveraging the numerous collaborative opportunities within the O’Neal Comprehensive Cancer Center
and UAB’s Cancer Control and Population Sciences program. Fellows will disseminate their work via peer-
reviewed publications and presentations at scientific conferences. Five required courses cover cancer
prevention and control topics, transdisciplinary research, research ethics, grant writing, diversity/equity/inclusion,
and one elective topic. New curricular innovations introduce transdisciplinary research, an approach to
creating new knowledge that builds upon standard team science methodologies via integrating new perspectives
provided by partners from not only academia, but also industry, government or community groups. To foster
transdisciplinary work, our training curriculum includes a new annual transdisciplinary science workshop and a
mini-sabbatical. Over the last 35 years, we have trained 171 cancer prevention and control scientists, 82.5%
of whom have launched successful careers, predominantly in cancer-related fields; and 35.6% of whom are NIH-
defined researchers from URM backgrounds. This track record demonstrates how seriously we take NIH’s goal
to train a diverse cancer-focused scientific workforce, and we are prepared to build upon this legacy of success.