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TRAINING IN THE IMMUNOBIOLOGY AND MOLECULAR CELL BIOLOGY OF CANCER

Award Number: T32CA009547
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 07/01/1986
PERIOD OF PERFORMANCE END DATE: 06/30/2027

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TRAINING IN THE IMMUNOBIOLOGY AND MOLECULAR CELL BIOLOGY OF CANCER - PROJECT ABSTRACT This revised application seeks renewal for years 36-40 of a T32 program that will provide training for 7 postdoctoral MD, PhD or MD/PhD scientists. The training program is centered in the Department of Pathology and Immunology (P&I) at Washington University in St. Louis, and consists of 36 training mentors who are housed in 10 different departments. The training faculty consists of 16 women and 20 men and includes 2 URM. The faculty are a highly interactive group of immunologists with interests in cancer immunology and cell/molecular cancer biology and are led by a director and associate director who are well known for their contributions to cancer immunology/immunotherapy and their commitment to training of young scientists. The research of our faculty focuses on various aspects of cancer immunology and immunotherapy with an emphasis on the molecular basis of cellular activation and suppression. A Steering Committee of six T32 faculty members oversees the training program and is responsible for the selection and oversight of the trainees. We also formed a new external advisory board to obtain outside opinions on our T32 program. Training includes a 2-to 3-year period of full- time laboratory research, where the trainee is exposed to the latest approaches in cancer immunology and cell and molecular cancer biology. The training also includes presenting at laboratory meetings, participation in weekly seminars and yearly retreats, training in research ethics and rigor and reproducibility, participation in national/international meetings and opportunities to audit advanced courses in Immunology, Cell Biology and Cancer Biology. During the most recent 10-year funding period of this T32, 49 trainees were supported by the Program: 4 withdrew for personal reasons and 7 trainees who had just started the program had their work delayed by the COVID-19 pandemic. The remaining 38 trainees published 171 papers with 33 papers appearing in high impact journals and 76% of these trainees had at least one first-author paper. Of the 70 trainees who have been or are supported by this Program in the last 15 years, 66 (94%) have remained in research. These demographics document the success of our T32 Training Program and provide strong support for its competitive renewal.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $343,165 )
2025	2025	WASHINGTON UNIVERSITY, THE	1 BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Research Manpower	000	39	7/11/2025	NON-COMPETING CONTINUATION	$343,165
														Subtotal = $343,165

Issue Date FY: 2024 ( Subtotal = $416,112 )
2024	2024	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63110	SAINT LOUIS CITY	USA	Cancer Research Manpower	000	38	6/25/2024	NON-COMPETING CONTINUATION	$416,112
														Subtotal = $416,112

Issue Date FY: 2023 ( Subtotal = $379,475 )
2023	2023	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Research Manpower	000	37	6/27/2023	NON-COMPETING CONTINUATION	$379,475
														Subtotal = $379,475

Issue Date FY: 2022 ( Subtotal = $394,366 )
2022	2022	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Research Manpower	000	36	7/6/2022	COMPETING CONTINUATION	$394,366
2022	2022	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Research Manpower	002	36	9/27/2022	COMPETING CONTINUATION	$24,220
2022	2020	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Research Manpower	001	35	9/27/2022	NON-COMPETING CONTINUATION	-$24,220
														Subtotal = $394,366

Issue Date FY: 2020 ( Subtotal = $530,056 )
2020	2020	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Research Manpower	000	35	3/20/2020	NON-COMPETING CONTINUATION	$530,056
														Subtotal = $530,056

Issue Date FY: 2019 ( Subtotal = $598,865 )
2019	2019	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Research Manpower	000	34	4/1/2019	NON-COMPETING CONTINUATION	$598,865
														Subtotal = $598,865

Issue Date FY: 2018 ( Subtotal = $535,845 )
2018	2018	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Research Manpower	000	33	4/27/2018	NON-COMPETING CONTINUATION	$516,444
2018	2018	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Research Manpower	001	33	5/24/2018	NON-COMPETING CONTINUATION	$19,401
														Subtotal = $535,845

Issue Date FY: 2017 ( Subtotal = $566,042 )
2017	2017	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Research Manpower	000	31	4/14/2017	SUPPLEMENT FOR EXPANSION	$12,861
2017	2017	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Research Manpower	001	32	4/27/2017	NON-COMPETING CONTINUATION	$549,211
2017	2017	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Research Manpower	002	32	8/10/2017	NON-COMPETING CONTINUATION	$3,970
														Subtotal = $566,042

Issue Date FY: 2016 ( Subtotal = $520,900 )
2016	2016	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Cancer Research Manpower	000	31	5/13/2016	COMPETING CONTINUATION	$418,118
2016	2016	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Cancer Research Manpower	001	31	5/27/2016	COMPETING CONTINUATION	$102,782
														Subtotal = $520,900

Issue Date FY: 2015 ( Subtotal = $493,819 )
2015	2015	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Cancer Research Manpower	000	30	4/10/2015	NON-COMPETING CONTINUATION	$493,819
														Subtotal = $493,819

Issue Date FY: 2014 ( Subtotal = $593,659 )
2014	2014	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Cancer Research Manpower	000	29	4/15/2014	NON-COMPETING CONTINUATION	$593,659
														Subtotal = $593,659

Issue Date FY: 2013 ( Subtotal = $583,887 )
2013	2013	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Cancer Research Manpower	000	28	5/9/2013	NON-COMPETING CONTINUATION	$583,887
														Subtotal = $583,887

Issue Date FY: 2012 ( Subtotal = $556,168 )
2012	2012	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Cancer Research Manpower	000	27	4/17/2012	NON-COMPETING CONTINUATION	$556,168
														Subtotal = $556,168

Issue Date FY: 2011 ( Subtotal = $396,471 )
2011	2011	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Cancer Research Manpower	000	26	6/7/2011	COMPETING CONTINUATION	$396,471
														Subtotal = $396,471

Issue Date FY: 2010 ( Subtotal = $402,831 )
2010	2010	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Cancer Research Manpower	000	25	4/21/2010	NON-COMPETING CONTINUATION	$402,831
														Subtotal = $402,831

Issue Date FY: 2009 ( Subtotal = $322,249 )
2009	2009	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Cancer Research Manpower	000	24	4/29/2009	NON-COMPETING CONTINUATION	$322,249
														Subtotal = $322,249

Issue Date FY: 2008 ( Subtotal = $509,782 )
2008	2008	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Cancer Research Manpower	000	23	4/25/2008	NON-COMPETING CONTINUATION	$509,782
														Subtotal = $509,782

Issue Date FY: 2007 ( Subtotal = $513,905 )
2007	2007	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Cancer Research Manpower	000	22	4/24/2007	NON-COMPETING CONTINUATION	$513,905
														Subtotal = $513,905

Issue Date FY: 2006 ( Subtotal = $426,496 )
2006	2006	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Cancer Research Manpower	000	21	5/19/2006	COMPETING CONTINUATION	$426,496
														Subtotal = $426,496

Issue Date FY: 2004 ( Subtotal = $423,779 )
2004	2004	WASHINGTON UNIVERSITY	7425 FORSYTH	CLAYTON	MO	63105	SAINT LOUIS	USA	Cancer Research Manpower	000	19	6/18/2004	NON-COMPETING CONTINUATION	$423,779
														Subtotal = $423,779

Issue Date FY: 2003 ( Subtotal = $493,068 )
2003	2003	WASHINGTON UNIVERSITY	7425 FORSYTH	CLAYTON	MO	63105	SAINT LOUIS	USA	Cancer Research Manpower	000	18		NON-COMPETING CONTINUATION	$493,068
														Subtotal = $493,068

Issue Date FY: 2002 ( Subtotal = $462,756 )
2002	2002	WASHINGTON UNIVERSITY	7425 FORSYTH	CLAYTON	MO	63105	SAINT LOUIS	USA	Cancer Research Manpower	000	17	5/17/2002	NON-COMPETING CONTINUATION	$462,756
														Subtotal = $462,756

Grand Total All Awards = $11,917,131

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TRAINING IN THE IMMUNOBIOLOGY AND MOLECULAR CELL BIOLOGY OF CANCER

Award Number: T32CA009547

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 07/01/1986

PERIOD OF PERFORMANCE END DATE: 06/30/2027

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