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Program for AIDS Clinical Research Training (PACRT)

Award Number: T32AI007433
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 09/30/1992
PERIOD OF PERFORMANCE END DATE: 06/30/2027

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Program for AIDS Clinical Research Training (PACRT) - Project Summary Over the past 40 years, dramatic advances in the understanding of HIV infection and its therapy have transformed HIV into a highly treatable, chronic disease. Along with this evolution, critical questions have arisen about how basic research and clinical trials can best be linked to clinical epidemiology and outcomes research, both in the U.S. and internationally. The goal of the Program for AIDS Clinical Research Training (PACRT) — which has successfully trained multiple generations of leading HIV clinical investigators for the past 30 years — is to provide training in quantitative research methodologies with a focus on HIV clinical research to pre-doctoral PhD students and physician investigators at the most formative stages of their careers. This training has prepared both groups to conduct clinical research of the highest quality and of direct relevance to the prevention and treatment of HIV infection. These young investigators have made important and substantive contributions to the scientific literature and to HIV clinical care and policy, and a large majority have developed into successful independent investigators. In the next grant cycle, the PACRT trainees will receive two years of research training under the close supervision and mentorship of one or more of the 14 diverse and experienced program faculty members. Trainees will receive didactic training at the Harvard T.H. Chan School of Public Health or other Harvard University sites. Primary performance sites for the five post- doctoral fellows will be the Massachusetts General Hospital, Beth Israel Deaconess Medical Center, Brigham and Women's Hospital, Boston Children’s Hospital, and Harvard Medical School. The primary site for the two pre-doctoral fellows will be the Harvard T.H. Chan School of Public Health. This program has three specific aims for its trainees: 1) To acquire a sufficient body of knowledge of quantitative methods to conduct independent research in: clinical epidemiology, outcomes research, implementation science, cost-effectiveness analysis, and/or clinical trials in HIV. 2) To foster the creation of important scientific contributions with the close and longitudinal mentorship of program faculty. 3) To develop a primary research focus and broad understanding of the various aspects of HIV disease for novel interdisciplinary investigation, leading to a successful career focused on HIV research.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $664,571 )
2025	2025	THE GENERAL HOSPITAL CORPORATION	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Allergy and Infectious Diseases Research	001	34	8/22/2025	NON-COMPETING CONTINUATION	$664,571
2025	2024	THE GENERAL HOSPITAL CORPORATION	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	33	12/23/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $664,571

Issue Date FY: 2024 ( Subtotal = $633,169 )
2024	2024	THE GENERAL HOSPITAL CORPORATION	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	33	5/8/2024	NON-COMPETING CONTINUATION	$633,169
														Subtotal = $633,169

Issue Date FY: 2023 ( Subtotal = $594,418 )
2023	2023	THE GENERAL HOSPITAL CORPORATION	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Allergy and Infectious Diseases Research	005	32	6/29/2023	NON-COMPETING CONTINUATION	$636,728
2023	2022	THE GENERAL HOSPITAL CORPORATION	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Allergy and Infectious Diseases Research	004	31	6/1/2023	COMPETING CONTINUATION	$219,596
2023	2021	THE GENERAL HOSPITAL CORPORATION	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Allergy and Infectious Diseases Research	003	30	6/1/2023	NON-COMPETING CONTINUATION	-$6,666
2023	2021	THE GENERAL HOSPITAL CORPORATION	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Allergy and Infectious Diseases Research	002	30	5/15/2023	NON-COMPETING CONTINUATION	-$212,930
2023	2017	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	26	10/1/2022	COMPETING CONTINUATION	-$3,300
2023	2017	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	001	26	10/1/2022	COMPETING CONTINUATION	-$39,011
														Subtotal = $594,418

Issue Date FY: 2022 ( Subtotal = $617,250 )
2022	2022	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Allergy and Infectious Diseases Research	001	31	7/29/2022	COMPETING CONTINUATION	$617,250
2022	2021	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	30	7/22/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $617,250

Issue Date FY: 2021 ( Subtotal = $687,100 )
2021	2021	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Allergy and Infectious Diseases Research	002	30	9/17/2021	NON-COMPETING CONTINUATION	$101,139
2021	2021	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Allergy and Infectious Diseases Research	001	30	5/24/2021	NON-COMPETING CONTINUATION	$576,050
2021	2020	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	29	5/21/2021	NON-COMPETING CONTINUATION	$9,911
														Subtotal = $687,100

Issue Date FY: 2020 ( Subtotal = $558,737 )
2020	2020	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	29	5/14/2020	NON-COMPETING CONTINUATION	$558,737
														Subtotal = $558,737

Issue Date FY: 2019 ( Subtotal = $541,740 )
2019	2019	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Allergy and Infectious Diseases Research	003	28	5/2/2019	NON-COMPETING CONTINUATION	$541,740
2019	2018	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Allergy and Infectious Diseases Research	001	27	1/11/2019	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$249,877
2019	2018	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Allergy and Infectious Diseases Research	002	27	2/1/2019	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2019	2017	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	26	1/11/2019	COMPETING CONTINUATION	-$249,877
2019	2015	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	004	24	6/24/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $541,740

Issue Date FY: 2018 ( Subtotal = $535,885 )
2018	2018	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Allergy and Infectious Diseases Research	004	27	5/23/2018	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$535,885
2018	2017	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	001	26	10/24/2017	COMPETING CONTINUATION	$215,915
2018	2017	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	002	24	10/24/2017	SUPPLEMENT FOR EXPANSION	-$2,926
2018	2017	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	003	25	10/24/2017	SUPPLEMENT FOR EXPANSION	-$2,592
2018	2016	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	25	10/24/2017	EXTENSION WITH OR WITHOUT FUNDS	-$210,397
														Subtotal = $535,885

Issue Date FY: 2017 ( Subtotal = $488,623 )
2017	2017	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	004	24	3/16/2017	SUPPLEMENT FOR EXPANSION	$2,926
2017	2017	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	003	24	3/8/2017	SUPPLEMENT FOR EXPANSION	-$2,926
2017	2017	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	006	25	8/15/2017	SUPPLEMENT FOR EXPANSION	$2,592
2017	2017	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	005	26	7/12/2017	COMPETING CONTINUATION	$483,105
2017	2017	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	002	24	3/3/2017	SUPPLEMENT FOR EXPANSION	$2,926
2017	2016	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	001	25	1/23/2017	EXTENSION WITH OR WITHOUT FUNDS	$164,572
2017	2015	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	24	1/23/2017	NON-COMPETING CONTINUATION	-$164,572
														Subtotal = $488,623

Issue Date FY: 2016 ( Subtotal = $427,991 )
2016	2016	HARVARD UNIVERSITY, SCHOOL OF PUBLIC HEALTH	55 SHATTUCK STREET	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	25	4/20/2016	EXTENSION WITH OR WITHOUT FUNDS	$427,991
														Subtotal = $427,991

Issue Date FY: 2015 ( Subtotal = $440,253 )
2015	2015	HARVARD UNIVERSITY, SCHOOL OF PUBLIC HEALTH	55 SHATTUCK STREET	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	24	5/8/2015	NON-COMPETING CONTINUATION	$440,253
														Subtotal = $440,253

Issue Date FY: 2014 ( Subtotal = $435,105 )
2014	2014	HARVARD UNIVERSITY, SCHOOL OF PUBLIC HEALTH	55 SHATTUCK STREET	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	23	5/21/2014	NON-COMPETING CONTINUATION	$435,105
														Subtotal = $435,105

Issue Date FY: 2013 ( Subtotal = $432,257 )
2013	2013	HARVARD UNIVERSITY, SCHOOL OF PUBLIC HEALTH	55 SHATTUCK STREET	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	22	5/17/2013	NON-COMPETING CONTINUATION	$432,257
														Subtotal = $432,257

Issue Date FY: 2012 ( Subtotal = $419,495 ) (Continued on the next page)
Grand Total All Awards = $10,799,421

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Program for AIDS Clinical Research Training (PACRT)

Award Number: T32AI007433

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 09/30/1992

PERIOD OF PERFORMANCE END DATE: 06/30/2027

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