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 | Issue Date FY: 2023 ( Subtotal = $164,916,797 ) (Continued on the next page) |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | S10OD032278 | A microscope for ultra-high multiplex spatial imaging of transcripts and proteins in tissues | 000 | 1 | NIH | 3/28/2023 | $299,500 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21AA030640 | Sensitive periods for prenatal alcohol exposure: a longitudinal study of DNA methylation and subsequent mental health | 000 | 1 | NIH | 3/17/2023 | $199,500 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG079838 | A unique subpopulation of wild-type neurons recapitulating FAD phenotypes | 001 | 1 | NIH | 3/13/2023 | $0 |
| | 2023 | 2023 | MASSACHUSETTS GENERAL HOSPITAL, THE | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23NS128164 | A Culturally-Adapted, Trauma-Informed Cognitive Rehabilitation Intervention for Asylum-Seekers and Refugees with Traumatic Brain Injury | 000 | 1 | NIH | 11/28/2022 | $200,880 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | S10OD034258 | Console Upgrade for 4.7T PET-MRI Preclinical Scanner | 000 | 1 | NIH | 2/27/2023 | $600,000 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HL162928 | The Role of Arylsulfatase in Vascular Calcification | 000 | 1 | NIH | 3/17/2023 | $709,203 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG079838 | A unique subpopulation of wild-type neurons recapitulating FAD phenotypes | 000 | 1 | NIH | 2/22/2023 | $518,738 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R00NS118120 | Probing the Biophysical Basis of Large-Scale Brain Dynamics Using Simultaneous PET/fMRI and EEG/PET/fMRI | 000 | 3 | NIH | 2/24/2023 | $249,000 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01CA279385 | Role of the YAP1-LATS2 negative feedback loop in cervical carcinogenesis | 000 | 1 | NIH | 3/17/2023 | $419,573 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HL162373 | Statistical Methods in COVID-19/PASC Clinical Research | 001 | 1 | NIH | 3/15/2023 | -$2,605 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R00NS118120 | Probing the Biophysical Basis of Large-Scale Brain Dynamics Using Simultaneous PET/fMRI and EEG/PET/fMRI | 001 | 3 | NIH | 3/16/2023 | -$1,434 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23AR080791 | Predictive modeling of cutaneous immune checkpoint inhibitor toxicities | 000 | 1 | NIH | 2/24/2023 | $176,040 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HL162373 | Statistical Methods in COVID-19/PASC Clinical Research | 000 | 1 | NIH | 3/6/2023 | $437,707 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21AI176580 | Trained Immunity in the Airway Mucosa Differentiates Asthma from Allergy Alone | 000 | 1 | NIH | 2/15/2023 | $252,000 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AI176533 | Investigating the Protective Efficacy of SIV/HIV T and B cell Immunity Induced by RNA Replicons | 000 | 1 | NIH | 3/1/2023 | $926,410 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01CA276116 | Mechanisms of aggressive Rhabdomyosarcoma. | 000 | 1 | NIH | 3/1/2023 | $539,997 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21ES034468 | Applications of the long-term culture human primordial germ cell-like cells to toxicological assessments and mechanistic studies on chemically caused heritable human health threats | 000 | 1 | NIH | 3/27/2023 | $250,500 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AI173030 | Human NLRP11 function in non-canonical inflammasome activation by bacterial pathogen LPS | 000 | 1 | NIH | 3/6/2023 | $530,908 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R00HD101553 | Fast motion-robust fetal neuroimaging with MRI | 000 | 3 | NIH | 3/1/2023 | $249,000 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | T32HL166133 | Research Training in Global Non-Communicable Diseases | 001 | 1 | NIH | 2/23/2023 | -$209,428 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01MH131664 | A formal group theory-based model in primates for studying interactive social behavior and its dysfunction | 000 | 1 | NIH | 2/28/2023 | $500,511 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | DP1DA058360 | The neuropharmacology of brain activation during stages of drug abuse | 000 | 1 | NIH | 2/16/2023 | $504,000 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K99HD107222 | Characterizing the genetic etiology of delayed puberty with integrative genomic techniques | 000 | 1 | NIH | 3/2/2023 | $135,886 |
| | 2023 | 2023 | MASSACHUSETTS GENERAL HOSPITAL, THE | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K99AG076877 | Neural Circuits Underlying Post-operative Delirium in Early Stage Alzheimer's Disease | 000 | 1 | NIH | 12/13/2022 | $135,234 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21CA267222 | 3D Fourier Imaging System for High Throughput Analyses of Cancer Organoids | 000 | 2 | NIH | 2/22/2023 | $192,424 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K99CA278696 | Chromatin regulators of stemness and therapy resistance in rhabdomyosarcoma | 000 | 1 | NIH | 3/27/2023 | $178,200 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23AT012364 | Web-based mind-body treatment to enhance resilience among patients with painful nontraumatic upper extremity conditions and comorbid risky substance use | 000 | 1 | NIH | 3/24/2023 | $170,157 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K08CA270202 | Predictive markers for personalized therapy in chronic lymphocytic leukemia | 000 | 1 | NIH | 3/27/2023 | $285,931 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K02DA056613 | Leveraging community-based participatory research and infoveillance to advance the science on recovery community centers serving Black communities | 000 | 1 | NIH | 3/24/2023 | $131,220 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | S10OD032184 | Next-generation 3 Tesla Human MRI System | 000 | 1 | NIH | 3/21/2023 | $2,000,000 |
| | 2023 | 2023 | MASSACHUSETTS GENERAL HOSPITAL, THE | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23NS118048 | Clinical and Non-Invasive Biomarkers of Myotonic Dystrophy | 000 | 1 | NIH | 12/12/2022 | $200,880 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21AG068767 | Exploring Determinants of Intrinsic DNA Load Towards Inflammaging | 000 | 2 | NIH | 3/6/2023 | $204,560 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R03DK129635 | Metabolomic Investigation of the Impact of Growth Hormone on Nonalcoholic Fatty Liver Disease: Identification of Novel Biomarkers and Therapeutic Targets | 000 | 2 | NIH | 3/16/2023 | $126,000 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01CA280968 | Targeting parathyroid glands with novel fluorophores for intraoperative imaging | 000 | 5 | NIH | 3/29/2023 | $733,271 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AI176658 | In vivo Monitoring of Neutrophil Function in Patients after Stem Cell Transplant | 000 | 1 | NIH | 2/13/2023 | $817,016 |
| | 2023 | 2023 | MASSACHUSETTS GENERAL HOSPITAL, THE | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21CA260989 | Microfluidic Apheresis to Isolate Circulating Tumor Clusters | 000 | 2 | NIH | 12/20/2022 | $176,716 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21CA260989 | Microfluidic Apheresis to Isolate Circulating Tumor Clusters | 001 | 2 | NIH | 3/21/2023 | $15,708 |
| | 2023 | 2023 | MASSACHUSETTS GENERAL HOSPITAL, THE | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23DK131322 | Investigating the impact of physical activity in modulating PCOS risk among peripubertal females | 000 | 1 | NIH | 12/21/2022 | $194,194 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K00AG068442 | Cellular and molecular changes in the spinal cord that cause motor deficits in old age | 000 | 3 | NIH | 1/26/2023 | $75,600 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R61NS126700 | A Novel Neuroprotectant to Reduce Ischemic Injury | 000 | 1 | NIH | 1/31/2023 | $408,375 |
| | 2023 | 2023 | MASSACHUSETTS GENERAL HOSPITAL, THE | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HL149647 | Cardiac resident macrophages in AV node conduction | 000 | 2 | NIH | 11/8/2022 | $652,074 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS126280 | Extracellular Mitochondria Transfer in Gray and White Matter for Ameliorating Sensorimotor and Cognitive Deficits After Stroke | 000 | 2 | NIH | 2/1/2023 | $503,023 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K00AG068442 | Cellular and molecular changes in the spinal cord that cause motor deficits in old age | 001 | 3 | NIH | 3/16/2023 | $75,600 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K00AG068442 | Cellular and molecular changes in the spinal cord that cause motor deficits in old age | 001 | 3 | NIH | 3/16/2023 | -$75,600 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AI153068 | The Immunopathogenesis of Familial Transverse Myelitis Due to Mutations in VPS37a | 000 | 1 | NIH | 1/31/2023 | $417,500 |
| | 2023 | 2023 | MASSACHUSETTS GENERAL HOSPITAL, THE | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HL163273 | Long-Acting, Short-Residing Nanochelators for Iron Overload Therapy | 000 | 1 | NIH | 12/22/2022 | $734,218 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HL149647 | Cardiac resident macrophages in AV node conduction | 001 | 2 | NIH | 2/17/2023 | $72,452 |
| | 2023 | 2023 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21MH129030 | Evaluating teeth as fossil records of children's prenatal/perinatal trauma exposure and future mental health risk | 000 | 2 | NIH | 3/3/2023 | $229,375 |
| | 2023 | 2023 | MASSACHUSETTS GENERAL HOSPITAL, THE | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | RF1NS127407 | Resolving the Role of Neuronal STING in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia | 000 | 1 | NIH | 1/5/2023 | $2,085,362 |
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