| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2025 ( Subtotal = $19,726,243 ) (Continued on the next page) |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21AI180866 | Does age matter for the development of pathogenic T helper 2 resident memory cells in the lung? | 000 | 2 | NIH | 11/5/2024 | $202,488 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AI179741 | Non-Templated Regulation of IgE Mediated Anaphylaxis | 000 | 2 | NIH | 11/7/2024 | $805,824 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23HL148017 | Testing the feasibility and preliminary efficacy of a psychological and behavioral intervention to promote physical activity after weight loss surgery | 000 | 5 | NIH | 11/6/2024 | $175,999 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AI177414 | Staphylococcal protease-mediated epithelial barrier perturbation and allergen sensitization | 000 | 2 | NIH | 11/7/2024 | $635,901 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23AG084868 | Elevated systolic blood pressure, body mass index, and amyloid as drivers of tau and cognitive decline in preclinical Alzheimers disease: critical windows in mid- to late-life | 000 | 2 | NIH | 11/8/2024 | $195,145 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R37CA260062 | Deciphering the Role of Reductive Stress in Non Small Cell Lung Cancer | 000 | 4 | NIH | 11/6/2024 | $345,870 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R03AI188350 | Molecular Imaging to Identify Regulators of G-protein Signaling Proteins in Human Neutrophils and Their Role in Vasculitis | 000 | 1 | NIH | 11/15/2024 | $80,995 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R00NS118120 | Probing the Biophysical Basis of Large-Scale Brain Dynamics Using Simultaneous PET/fMRI and EEG/PET/fMRI | 000 | 5 | NIH | 11/15/2024 | $222,767 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23AI151556 | Systems approach to elucidate the microbiome's influence on the development of food allergies early in life | 000 | 5 | NIH | 11/15/2024 | $199,800 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | AY2AX000061 | Patient-Centric Integrated Clinical Environment Platform for the Acceleration of Rural Access to Distributed and Integrated Medical Care (PARADIGM-ICE) | 000 | 1 | NIH | 11/15/2024 | $9,153,873 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | AY2AX000060 | A Rugged Non-Rotating CT Scanner for Rural Deployment and Population Screening | 000 | 1 | NIH | 11/15/2024 | $7,103,633 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23MH122676 | Neuroinflammation and Executive Function in Bipolar Disorder: A PET-fMRI Study | 000 | 5 | NIH | 11/14/2024 | $199,800 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K01AG084820 | Neurogenetic contributions to the spread of tau pathology in sporadic early-onset Alzheimer's disease | 000 | 2 | NIH | 11/14/2024 | $129,075 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23DK131322 | Investigating the impact of physical activity in modulating PCOS risk among peripubertal females | 000 | 3 | NIH | 11/13/2024 | $193,167 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K99DC022305 | Subtyping tinnitus based on fMRI dynamic functional connectivity | 000 | 1 | NIH | 11/13/2024 | $134,730 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K22CA282019 | Boosting IL-12-induced anti-glioblastoma activity via immunotherapeutic extracellular vesicles. | 000 | 2 | NIH | 11/1/2024 | $160,561 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AI175345 | Antibody mediated immunity against Klebsiella pneumoniae | 000 | 2 | NIH | 10/31/2024 | $693,822 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AI155630 | Structural and functional characterization of protective antibodies induced in peanut oral immunotherapy | 000 | 5 | NIH | 10/24/2024 | $487,562 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AI151178 | Defining functional humoral correlates of immunity to guide vaccine design | 000 | 5 | NIH | 11/4/2024 | $788,432 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01DK140244 | Control of allelic Gsα expression for regulating hormone signaling | 000 | 1 | NIH | 10/18/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23HL150331 | Vascular Leak and Outcomes in IPF | 000 | 5 | NIH | 10/25/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K08AI155830 | Intrinsic modifiers of beta-lactam resistance in nosocomial Enterobacterales | 000 | 4 | NIH | 10/18/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG082698 | A deep learning algorithm to detect signs of cognitive impairment in electronic health records | 001 | 1 | NIH | 11/17/2024 | -$300,358 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG082698 | A deep learning algorithm to detect signs of cognitive impairment in electronic health records | 000 | 1 | NIH | 10/15/2024 | $571,861 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R34DA057604 | Planning grant for a multi-site trial to examine the effectiveness of recovery community centers serving Black communities to support persons using medications for opioid use disorder | 000 | 1 | NIH | 10/8/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS138257 | Measuring Brain Complexity to Detect and Predict Recovery of Consciousness in the ICU | 000 | 1 | NIH | 10/24/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K99HL171884 | Functions and Mechanisms of Lung Microfold cells during Invasive Pneumococcal Disease | 000 | 1 | NIH | 10/26/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | P30AG062421 | Massachusetts Alzheimer's Disease Research Center (MADRC) | 001 | 6 | NIH | 11/13/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | P30AG062421 | Massachusetts Alzheimer's Disease Research Center (MADRC) | 000 | 6 | NIH | 10/18/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21EB032932 | High-Resolution Lymphatic Mapping of the Upper Extremities with MRI | 000 | 3 | NIH | 10/24/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | P01CA261669 | Digital Twin for Radiation-Induced Immune Suppression Estimation and Reduction | 000 | 4 | NIH | 10/18/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | U01AG087103 | Examining sex-differences in puberty and brain development in carriers of autosomal dominant Alzheimer's disease | 000 | 1 | NIH | 10/18/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01DC020247 | RTSS-Voice: Towards a unified system to classify treatments for muscle tension dysphonia | 001 | 3 | NIH | 11/7/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01DC020247 | RTSS-Voice: Towards a unified system to classify treatments for muscle tension dysphonia | 000 | 3 | NIH | 10/9/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HL151293 | Avoiding (Heart) Failure: Physiologic-Based Targeting of the RAAS to Treat Subclinical HFpEF among PWH | 000 | 5 | NIH | 10/14/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HL151293 | Avoiding (Heart) Failure: Physiologic-Based Targeting of the RAAS to Treat Subclinical HFpEF among PWH | 001 | 5 | NIH | 10/24/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG058063 | Harnessing Diverse Bioinformatic Approaches To Repurpose Drugs For Alzheimers Disease And Related Dementias | 002 | 7 | NIH | 10/24/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | U54EB033650 | Center for Innovative NeuroTech Advancement - CINTA | 000 | 3 | NIH | 10/15/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K25EB032864 | Super-resolved multiphoton microscopy with dual output ultrafast laser | 000 | 2 | NIH | 10/24/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21EB034798 | Non-rotating nano-optic endoscope for 360 degree in vivo imaging | 000 | 1 | NIH | 10/23/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01CA282223 | Randomized clinical trial to test the efficacy of a smartphone app for smoking cessation for nondaily smokers | 000 | 2 | NIH | 10/23/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23AT011922 | Development and feasibility of a mind-body intervention to improve physical activity for patients with chronic hip pain | 000 | 3 | NIH | 10/15/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01DE033520 | Molecular mechanisms controlling tooth development | 000 | 1 | NIH | 10/17/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R00AG066819 | Controlling oscillations to treat Alzheimers disease targeting the basal forebrain parvalbuminsystem | 000 | 3 | NIH | 10/10/2024 | $232 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21AG089842 | Potential of Dried Blood Spots for Measurement of Alzheimer's Disease Biomarkers | 000 | 1 | NIH | 10/10/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | T32AI007061 | Infectious Disease and Basic Microbiological Mechanisms | 001 | 46 | NIH | 10/10/2024 | $275,097 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01CE003686 | CE24-012 - Evaluating Telehealth's Role in Buprenorphine Treatment Initiation and Retention, Overdose Mortality, and Access Equity: An Analysis for Policy Development | 01 | 1 | CDC | 11/18/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R35GM152187 | Anesthesia and Consciousness | 000 | 1 | NIH | 11/5/2024 | $0 |
| | 2025 | 2024 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | NU50CK000622 | Novel Approaches to Integrating IPC Education, Workflows, and Assessment for Diverse Learners | 03 | 3 | CDC | 11/1/2024 | $0 |
|
