| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2025 ( Subtotal = $333,029,159 ) (Continued on the next page) |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R00AG059946 | High-throughput optical investigation into intact large-scale nervous systems for Alzheimers disease | 000 | 5 | NIH | 3/18/2025 | $224,097 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01EB034274 | Integrated, dynamic B0 and flip-angle shimming using multi-coil shim arrays | 001 | 2 | NIH | 6/25/2025 | $72,811 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01EB034274 | Integrated, dynamic B0 and flip-angle shimming using multi-coil shim arrays | 000 | 2 | NIH | 2/19/2025 | $655,298 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01DA053316 | Evaluation of Cannabidiol for Reduction of Brain Neuroinflammation | 001 | 5 | NIH | 4/11/2025 | $75,335 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01DA053316 | Evaluation of Cannabidiol for Reduction of Brain Neuroinflammation | 000 | 5 | NIH | 3/17/2025 | $678,014 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R24OD031955 | Developing preclinical xenograft models in zebrafish. | 000 | 4 | NIH | 2/25/2025 | $635,702 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | T32GM007592 | Research Training for Anesthetists | 004 | 47 | NIH | 6/18/2025 | $819,930 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01CA269672 | Reprogramming the tumormicroenvironment to improve immunotherapy of glioblastoma | 001 | 4 | NIH | 5/22/2025 | $37,964 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01CA289485 | Analyzing DNA replication and damage vulnerability in IDH mutant glioma | 001 | 2 | NIH | 5/22/2025 | $40,112 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01CA269672 | Reprogramming the tumormicroenvironment to improve immunotherapy of glioblastoma | 000 | 4 | NIH | 3/3/2025 | $341,670 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01CA289485 | Analyzing DNA replication and damage vulnerability in IDH mutant glioma | 000 | 2 | NIH | 3/3/2025 | $361,028 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | U01MD014023 | Racial disparities in police use of deadly force as a cause of racial disparities in sleep health across the life course | 000 | 5 | NIH | 2/20/2025 | $499,615 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K08AI193073 | Extracellular matrix stiffness control of NLRP3 inflammasome activity | 000 | 1 | NIH | 7/1/2025 | $197,160 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HL109448 | PET Imaging of Thrombus | 000 | 12 | NIH | 2/20/2025 | $725,992 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01ES035401 | Environmental chemicals impair epigenetic suppression of the endogenous retrovirus HML-2 in human primordial germ cells, predisposing the next generation to malignancies through HML-2 reactivation | 000 | 2 | NIH | 3/6/2025 | $604,191 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01CA129933 | Modeling Metastasis and Acquired Drug Resistance Using Circulating Tumor Cells | 001 | 18 | NIH | 5/23/2025 | $42,000 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01CA129933 | Modeling Metastasis and Acquired Drug Resistance Using Circulating Tumor Cells | 000 | 18 | NIH | 3/5/2025 | $378,000 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG079142 | Building predictive algorithms to identify resilience and resistance to Alzheimer's disease | 001 | 3 | NIH | 6/17/2025 | $78,570 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG079142 | Building predictive algorithms to identify resilience and resistance to Alzheimer's disease | 000 | 3 | NIH | 3/6/2025 | $883,899 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HL168090 | Brain-immune crosstalk in myocardial infarction | 003 | 3 | NIH | 7/9/2025 | $76,271 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01MH125802 | Defining Neurobiological Subtypes of Motor Functional Neurological Disorder | 000 | 5 | NIH | 3/6/2025 | $661,960 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HL168090 | Brain-immune crosstalk in myocardial infarction | 002 | 3 | NIH | 4/30/2025 | $686,432 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R00HG012222 | An integrative approach to disease gene discovery combining genetic variation, gene expression, and epigenetics. | 001 | 4 | NIH | 4/29/2025 | $24,899 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R00HG012222 | An integrative approach to disease gene discovery combining genetic variation, gene expression, and epigenetics. | 000 | 4 | NIH | 3/5/2025 | $224,101 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23DK140642 | Patient-Reported Outcome Measure (PROM) Utilization to Advance Patient Centered CKD Care | 000 | 1 | NIH | 7/2/2025 | $199,130 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | UM1DK078616 | TOPMed Omics of Type 2 Diabetes and Quantitative Traits | 000 | 17 | NIH | 2/19/2025 | $661,878 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | UG3AI190113 | Antibiotic Allergy: Phenotypes, Endotypes, and Mechanisms | 000 | 1 | NIH | 7/3/2025 | $427,671 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NR019982 | Recovering Together: Building resiliency in dyads of patients with an acute brain injury admitted to the Neuroscience Intensive Care Unit and their informal caregivers | 002 | 5 | NIH | 6/13/2025 | $649,365 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | OT2NS138339 | Gene Therapy Consortium (GTC) for Gene-Based Clinical Trials Conducted within NeuroNEXT | 000 | 1 | NIH | 2/27/2025 | $164,828 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AR079110 | The role of neuroinflammation in human peripheral neuropathic pain | 001 | 3 | NIH | 6/9/2025 | $51,096 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS083534 | A Longitudinal Analysis Stream for FreeSurfer | 000 | 7 | NIH | 3/6/2025 | $644,219 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AR079110 | The role of neuroinflammation in human peripheral neuropathic pain | 000 | 3 | NIH | 2/17/2025 | $656,946 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21AI193280 | Sex differences in a cytokine controlling antibody class switch recombination | 000 | 1 | NIH | 7/8/2025 | $439,088 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21AI183051 | Role of cholinergic neuroimmune signaling pathway disruption in the pathogenesis of Hirschsprung-associated enterocolitis | 000 | 1 | NIH | 7/8/2025 | $439,216 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG083759 | Molecular Chemiluminescence Probes for Imaging of Amyloid beta in Animal Models | 001 | 2 | NIH | 6/17/2025 | $66,023 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R34DA063088 | Peer Recovery Coaching for Promoting Tobacco Abstinence in People with Opioid Use Disorder | 000 | 1 | NIH | 7/4/2025 | $742,500 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG083759 | Molecular Chemiluminescence Probes for Imaging of Amyloid beta in Animal Models | 000 | 2 | NIH | 3/5/2025 | $742,763 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | UM1AI144295 | Targeting T cell Subsets in Autoimmune Disease | 001 | 7 | NIH | 4/21/2025 | $333,918 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG057505 | Aging of Emotion Circuitry and Risk for Alzheimer's disease: Impact of Sex, Immunity, and Fetal Origins | 001 | 7 | NIH | 6/9/2025 | $134,930 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG057505 | Aging of Emotion Circuitry and Risk for Alzheimer's disease: Impact of Sex, Immunity, and Fetal Origins | 000 | 7 | NIH | 3/7/2025 | $1,517,961 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | U01MH136059 | JASPer-MH: Jointly Assessed Scalable Phenotypes for Mental Health | 000 | 2 | NIH | 2/18/2025 | $1,792,896 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01DK116716 | The role of salt inducible kinases in parathyroid hormone action in bone | 001 | 8 | NIH | 5/1/2025 | $442,486 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AI153142 | Single-cell genomic profiling to identify immune signatures of bacterial sepsis in humans | 000 | 5 | NIH | 2/13/2025 | $970,158 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | U19AI174967 | Novel Approaches to Inducing Lung Allograft Tolerance in NHPs | 000 | 3 | NIH | 2/13/2025 | $3,299,788 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01MH131687 | Characterization of schizophrenia liability genes in models of human microglial synaptic pruning | 000 | 3 | NIH | 3/14/2025 | $503,390 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01CA283214 | Interleukin 33 Regulation for Cancer Prevention in Chronic Inflammation | 001 | 2 | NIH | 5/22/2025 | $60,405 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01CA283214 | Interleukin 33 Regulation for Cancer Prevention in Chronic Inflammation | 000 | 2 | NIH | 3/14/2025 | $543,658 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | U01NS077179 | Clinical Coordinating Center for the Network of Excellence in Neuroscience Clinical Trials (NEXT - CCC) | 001 | 14 | NIH | 4/25/2025 | $1,180,472 |
| | 2025 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS117598 | Neuroprotective B Cell Immunotherapy for Contusion Traumatic Brain Injury | 000 | 5 | NIH | 3/4/2025 | $380,939 |
|
