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 | Issue Date FY: 2026 ( Subtotal = $13,296,786 ) (Continued on the next page) |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K08DK132516 | Machine learning-based methods for the analysis of microbial glycomes and proteomes in inflammatory bowel disease. | 000 | 4 | NIH | 12/18/2025 | $169,560 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01EB036507 | Developing next-generation imaging technologies for in-vivo mesoscale diffusion MRI and microstructure imaging | 001 | 2 | NIH | 12/5/2025 | $519,456 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HG012867 | Integrating genomic data and protein structures to improve measures of selective constraint | 000 | 3 | NIH | 12/12/2025 | $828,512 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01MH128421 | Near real-time system for high-resolution computationalTMS navigation | 000 | 5 | NIH | 12/11/2025 | $783,657 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS102423 | Assembling the Genetic Architecture of X-linked Dystonia Parkinsonism | 000 | 8 | NIH | 12/19/2025 | $596,032 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS032196 | Analysis of Calcium Signaling in C. Elegans | 000 | 32 | NIH | 12/12/2025 | $527,572 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS122163 | Immuno-Cell Therapy for Brain Tumors | 000 | 5 | NIH | 12/19/2025 | $537,826 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS124679 | Preventing and Reversing Mitochondrial Leigh Syndrome with Hypoxia | 000 | 5 | NIH | 12/12/2025 | $446,502 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS126187 | Co-Targeting IL-6 and EGFRsignaling for the Treatment of Schwannomatosis and Associated Pain | 000 | 4 | NIH | 12/12/2025 | $429,559 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS131281 | Targeting Receptor Interacting Protein Kinase-1 in the Chronic Period of Intracerebral Hemorrhage | 000 | 3 | NIH | 12/12/2025 | $330,472 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS131281 | Targeting Receptor Interacting Protein Kinase-1 in the Chronic Period of Intracerebral Hemorrhage | 000 | 3 | NIH | 12/12/2025 | $97,478 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS131347 | Comparative Effectiveness of EEG-Guided Anti-Seizure Treatment in Acute Brain Injury | 000 | 3 | NIH | 12/16/2025 | $591,352 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS134799 | Mechanisms of Chronic Blood-Brain Barrier Dysfunction after Traumatic Brain Injury | 000 | 2 | NIH | 12/18/2025 | $363,690 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R03AI188350 | Molecular Imaging to Identify Regulators of G-protein Signaling Proteins in Human Neutrophils and Their Role in Vasculitis | 000 | 2 | NIH | 12/2/2025 | $83,500 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21NS140619 | Developing and Assessing Wearable MEG for Children | 000 | 2 | NIH | 12/12/2025 | $247,500 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21NS140800 | Red Blood Cell BPGM Deficiency Contributes to Cognitive Impairment Following Ischemic Stroke | 000 | 2 | NIH | 12/15/2025 | $200,400 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R37CA260062 | Deciphering the Role of Reductive Stress in Non Small Cell Lung Cancer | 000 | 5 | NIH | 12/10/2025 | $345,870 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AI177414 | Staphylococcal protease-mediated epithelial barrier perturbation and allergen sensitization | 000 | 3 | NIH | 12/4/2025 | $655,568 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AI179741 | Non-Templated Regulation of IgE Mediated Anaphylaxis | 000 | 3 | NIH | 12/2/2025 | $830,746 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AR082401 | Neuronal MRGPR signaling in itch and allergic skin inflammation | 000 | 3 | NIH | 12/3/2025 | $548,085 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG079838 | A unique subpopulation of wild-type neurons recapitulating FAD phenotypes | 000 | 4 | NIH | 12/17/2025 | $475,425 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG085562 | Development of sensitive PET tracers of pan-Amyloid-beta species for Alzheimer's disease | 000 | 3 | NIH | 12/15/2025 | $744,059 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG090302 | Thalamocortical interactions and the effect of thalamic stimulation on sleep oscillations | 000 | 2 | NIH | 12/17/2025 | $575,787 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AI187288 | GPCR biology in autoimmunity: bridging genetics to structure to decipher mechanisms of disease | 000 | 2 | NIH | 11/26/2025 | $813,644 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23DK131366 | Diet and metabolic factors in the pathogenesis of microscopic colitis | 000 | 5 | NIH | 12/18/2025 | $196,248 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23MD020098 | Variability in emergency demographic data and clinical outcomes | 000 | 2 | NIH | 12/12/2025 | $170,078 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23NS118048 | Clinical and Non-Invasive Biomarkers of Myotonic Dystrophy | 000 | 4 | NIH | 12/17/2025 | $200,880 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K99DC022305 | Subtyping tinnitus based on fMRI dynamic functional connectivity | 000 | 2 | NIH | 11/26/2025 | $134,730 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K08NS131530 | Causes and Consequences of Leptomeningeal Bleeding in Cerebral Amyloid Angiopathy | 000 | 3 | NIH | 12/12/2025 | $230,071 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K22CA282019 | Boosting IL-12-induced anti-glioblastoma activity via immunotherapeutic extracellular vesicles. | 000 | 3 | NIH | 12/15/2025 | $144,505 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01DK134675 | An NADH-ChREBP axis in fatty liver disease and dyslipidemia | 000 | 4 | NIH | 12/16/2025 | $502,691 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | P50AR080596 | Center of Research Translation on Osteoporosis Bone Anabolic Therapies | 001 | 4 | NIH | 12/12/2025 | $1,227,524 |
| | 2026 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K08AI193073 | Extracellular matrix stiffness control of NLRP3 inflammasome activity | 000 | 1 | NIH | 11/17/2025 | -$162,882 |
| | 2026 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | P30AG062421 | Massachusetts Alzheimer's Disease Research Center (MADRC) | 000 | 7 | NIH | 12/13/2025 | $0 |
| | 2026 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K25EB032864 | Super-resolved multiphoton microscopy with dual output ultrafast laser | 000 | 3 | NIH | 12/8/2025 | $0 |
| | 2026 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K99CA286969 | Breaching the Tumor-Immune Mechanical Barrier for Optimal Antitumor Immunity | 000 | 2 | NIH | 12/16/2025 | $0 |
| | 2026 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | P50HD104224 | The Massachusetts General Hospital Harvard Center for Reproductive Medicine | 000 | 5 | NIH | 12/2/2025 | $0 |
| | 2026 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R00AG083056 | Imaging brain-wide subarachnoid and perivascular cerebrospinal fluid flow in aging and Alzheimer's disease | 001 | 3 | NIH | 12/10/2025 | $0 |
| | 2026 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R00AG083056 | Imaging brain-wide subarachnoid and perivascular cerebrospinal fluid flow in aging and Alzheimer's disease | 000 | 3 | NIH | 12/2/2025 | $0 |
| | 2026 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R00AG080134 | Understanding the mechanistic link between vascular dysfunction and Alzheimers disease-related protein accumulation in the medial temporal lobe | 000 | 3 | NIH | 12/16/2025 | $0 |
| | 2026 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01DA050700 | Elucidating Mechanisms of Pregnancy's Protective Effect on Drug Abuse Using Integrated Data Analysis | 000 | 5 | NIH | 10/10/2025 | $0 |
| | 2026 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01CA299956 | Randomized Trial of a Targeted Palliative Care Intervention for Patients with Metastatic Breast Cancer | 000 | 1 | NIH | 11/26/2025 | $0 |
| | 2026 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01EB033321 | Universal optical coherence polarimetry | 000 | 4 | NIH | 12/15/2025 | $0 |
| | 2026 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01EB035394 | Optimizing Mobile Photon-Counting CT Image Quality via Deep Learning for Neuro Intensive Care Unit | 000 | 2 | NIH | 11/17/2025 | $0 |
| | 2026 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01EB036507 | Developing next-generation imaging technologies for in-vivo mesoscale diffusion MRI and microstructure imaging | 000 | 1 | NIH | 11/19/2025 | $0 |
| | 2026 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HD117068 | Understanding vulvodynia: Using machine-learning-based modeling to identify factors associated with resolution and persistence of vulvar pain | 000 | 1 | NIH | 11/19/2025 | $0 |
| | 2026 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HL109448 | PET Imaging of Thrombus | 000 | 12 | NIH | 11/7/2025 | $0 |
| | 2026 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HL157384 | Targeting durotaxis in lung injury and fibrosis | 000 | 4 | NIH | 10/14/2025 | $0 |
| | 2026 | 2025 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HL157635 | Using Electrocardiogram Genetics to Inform Arrhythmia Risk | 000 | 4 | NIH | 12/11/2025 | $0 |
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