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 | Issue Date FY: 2026 ( Subtotal = $95,430,425 ) (Continued on the next page) |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AI174276 | Eliminating the Immunogenicity of AAV Vectored HIV Antibody Delivery | 000 | 3 | NIH | 12/29/2025 | $469,586 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23AG084868 | Elevated systolic blood pressure, body mass index, and amyloid as drivers of tau and cognitive decline in preclinical Alzheimers disease: critical windows in mid- to late-life | 000 | 3 | NIH | 1/15/2026 | $196,731 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K01AG084820 | Neurogenetic contributions to the spread of tau pathology in sporadic early-onset Alzheimer's disease | 000 | 3 | NIH | 1/15/2026 | $129,075 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K01AG084816 | Identifying variations in gamma-secretase function that are critical determinants of clinical and biomarker progression of Autosomal Dominant Alzheimer's disease: From mechanism to clinical trials | 000 | 3 | NIH | 1/14/2026 | $129,166 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23MH132893 | The role of inflammation in cognitive dysfunction in acute depression as determined by experimental inhibition of tumor necrosis factor-alphasignaling in a randomized controlled trial. | 000 | 3 | NIH | 1/14/2026 | $197,564 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01EB031008 | Clinically Translatable MRI Reporter Genes and Imaging Methods with Ultra-High Specificity and Sensitivity | 000 | 6 | NIH | 1/9/2026 | $511,947 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HD102616 | Brainstem Arousal Network in Human Consciousness: Healthy development vs SIDS | 000 | 5 | NIH | 12/22/2025 | $627,723 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01DK120663 | Molecular Magnetic Resonance Imaging of Inflammation | 000 | 7 | NIH | 12/30/2025 | $703,386 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS127407 | Resolving the Role of Neuronal STING in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia | 000 | 2 | NIH | 3/5/2026 | $682,793 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R33HL173898 | Development of platform technology to measure kinetics and equilibrium concentration of sickle hemoglobin polymerization in single RBCs for drug potency assessment and patient risk stratification | 000 | 2 | NIH | 3/4/2026 | $467,102 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AT011429 | Neuroimaging the impact of respiration and respiratory-gated neuromodulation on human glymphatic physiology | 001 | 6 | NIH | 3/10/2026 | $797,704 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R35HL176359 | Macrophages in Cardiovascular Health | 000 | 2 | NIH | 2/26/2026 | $1,071,409 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG085562 | Development of sensitive PET tracers of pan-Amyloid-beta species for Alzheimer's disease | 001 | 3 | NIH | 2/26/2026 | $82,673 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23MH136873 | Engaging men outside the HIV prevention paradigm in rural South Africa | 000 | 2 | NIH | 3/5/2026 | $144,823 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R00AR080243 | Metabolic syndrome, chronic inflammation, and gout: a multi-omics approach | 000 | 4 | NIH | 12/23/2025 | $224,101 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG090302 | Thalamocortical interactions and the effect of thalamic stimulation on sleep oscillations | 001 | 2 | NIH | 3/9/2026 | $63,975 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG079838 | A unique subpopulation of wild-type neurons recapitulating FAD phenotypes | 001 | 4 | NIH | 2/25/2026 | $52,824 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | RM1NS128741 | From Nerve to Brain: Toward a Mechanistic Understanding of Spinal Cord Stimulation in Human Subjects | 000 | 2 | NIH | 2/27/2026 | $758,578 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R33GM148826 | Optimizing methods of clinical sample processing for scRNA-seq and mechanistic studies in sepsis to enable reliable, reproducible, and high-yield multi-center collection efforts | 001 | 4 | NIH | 3/10/2026 | $64,789 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23MH136873 | Engaging men outside the HIV prevention paradigm in rural South Africa | 001 | 2 | NIH | 3/9/2026 | $50,490 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG071567 | Microvascular Stress as a Pathway to Neurodegeneration in Alzheimer's | 001 | 5 | NIH | 2/25/2026 | $41,827 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23AT012789 | Pain Disengagement Training: A self-directed intervention for pain catastrophizing | 000 | 3 | NIH | 3/10/2026 | $170,510 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R03DA064903 | Uncovering Patterns in the Evolving Drug Supply to Detect Emerging Overdose Trends Using Machine Learning | 000 | 1 | NIH | 3/9/2026 | $330,000 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS126187 | Co-Targeting IL-6 and EGFRsignaling for the Treatment of Schwannomatosis and Associated Pain | 001 | 4 | NIH | 2/26/2026 | $47,730 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01DK134590 | A quantitative viability metric for liver transplantation using Resonance Raman Spectroscopy | 000 | 4 | NIH | 2/26/2026 | $497,564 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG082328 | Studying the pathogenic roles of human CD8+ T cells in Alzheimer's disease using a 3D human Peripheral immune Chip. | 001 | 3 | NIH | 2/26/2026 | $68,699 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG086263 | Characterizing microvascular impairment in adults with elevated genetic risk for Alzheimer's Disease | 001 | 2 | NIH | 2/25/2026 | $82,940 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01CA266275 | Automated interactive definition of the clinical target volume in radiation oncology | 000 | 5 | NIH | 3/9/2026 | $312,887 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R35GM152187 | Anesthesia and Consciousness | 001 | 3 | NIH | 3/10/2026 | $41,234 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS136224 | Brain Stimulation to Improve Neurocognitive Deficits After Subarachnoid Hemorrhage | 000 | 3 | NIH | 3/10/2026 | $502,462 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01DK121789 | Molecular Magnetic Resonance of Hepatic Fibrogenesis | 000 | 7 | NIH | 3/10/2026 | $706,400 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS131347 | Comparative Effectiveness of EEG-Guided Anti-Seizure Treatment in Acute Brain Injury | 001 | 3 | NIH | 2/26/2026 | $65,706 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21AI184169 | Impact of in utero HIV and antiretroviral exposure on the placenta and birth weight | 001 | 2 | NIH | 1/23/2026 | $11,187 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23AR080791 | Predictive modeling of cutaneous immune checkpoint inhibitor toxicities | 000 | 4 | NIH | 2/24/2026 | $176,040 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21AI184169 | Impact of in utero HIV and antiretroviral exposure on the placenta and birth weight | 000 | 2 | NIH | 1/22/2026 | $191,450 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K24HL163073 | Mentorship in patient-oriented research on behavioral and social determinants of cardiometabolic health | 000 | 4 | NIH | 2/23/2026 | $126,385 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG071173 | Biopsychosocial Mechanisms of Successful Aging | 001 | 5 | NIH | 2/24/2026 | $78,781 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | U19AI174967 | Novel Approaches to Inducing Lung Allograft Tolerance in NHPs | 000 | 4 | NIH | 2/5/2026 | $3,401,842 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG054598 | Astrocytes as governing pathological drivers of neurovascular dysfunction in AD | 000 | 9 | NIH | 3/3/2026 | $511,105 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG057505 | Aging of Emotion Circuitry and Risk for Alzheimer's disease: Impact of Sex, Immunity, and Fetal Origins | 000 | 8 | NIH | 3/3/2026 | $1,734,748 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R00HG012222 | An integrative approach to disease gene discovery combining genetic variation, gene expression, and epigenetics. | 000 | 5 | NIH | 3/4/2026 | $248,528 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K99DK139461 | Integration of dietary factors and multi-omic signatures of genetic subtypes to understand diabetes heterogeneity | 000 | 2 | NIH | 2/27/2026 | $90,000 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG086433 | New epigenetic inhibitors for Alzheimer's disease treatment | 000 | 3 | NIH | 3/3/2026 | $806,956 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS146113 | Non-Invasive Vagus Nerve Stimulation in Subarachnoid Hemorrhage | 000 | 1 | NIH | 1/21/2026 | $511,402 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG076704 | Metabolic Interventions for Sleep, Anesthesia-related Neurocognitive Disorders and Alzheimer's Disease | 000 | 5 | NIH | 3/6/2026 | $530,816 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | P01CA084203 | Photodynamic Priming of Cancer and Image-guidance for Optimal Immune Response | 000 | 20 | NIH | 3/6/2026 | $1,206,614 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01EY033360 | Proangiogenic M2-type macrophages and choroidal neovascularization | 000 | 4 | NIH | 1/21/2026 | $66,570 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R35GM152187 | Anesthesia and Consciousness | 000 | 3 | NIH | 12/22/2025 | $371,112 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01DC019653 | Studying semantic processing during language comprehension in humans at the single-cellular level | 000 | 5 | NIH | 3/4/2026 | $531,720 |
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