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 | Issue Date FY: 2026 ( Subtotal = $253,109,736 ) (Continued on the next page) |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG098906 | PET imaging of alpha-synuclein pathology | 000 | 1 | NIH | 2/4/2026 | $677,276 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG098476 | The Coma Family Program (COMA-F): A multi-site clinical trial of a resilience program for caregivers of patients with severe acute brain injury | 001 | 1 | NIH | 2/9/2026 | $0 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG098476 | The Coma Family Program (COMA-F): A multi-site clinical trial of a resilience program for caregivers of patients with severe acute brain injury | 000 | 1 | NIH | 2/3/2026 | $722,746 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01MH140004 | Enhancing Suicide Risk Detection through Computer Vision: a Novel Approach to Tissue Damage Analysis in Emergency Care | 000 | 1 | NIH | 3/6/2026 | $839,023 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AI195539 | Elicitation of pan-influenza A antibodies via simple B cell development pathways | 000 | 1 | NIH | 2/6/2026 | $661,313 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS127407 | Resolving the Role of Neuronal STING in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia | 000 | 2 | NIH | 3/5/2026 | $682,793 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K08DA065497 | Clinical Impact and Cost-Effectiveness of Integrating Infectious Disease Care into Rapid-Access Substance Use Bridge Clinics | 000 | 1 | NIH | 2/17/2026 | $197,640 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | U01NS142895 | Targeted Gene Repair Therapy for Multisystemic Smooth Muscle Dysfunction Syndrome (MSMDS) Caused by ACTA2 R179H Mutation | 000 | 1 | NIH | 5/5/2026 | $2,541,084 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | S10OD040131 | VisualSonics Vevo F2 LAZR-X20 Photoacoustic and Ultrasound Imaging System | 000 | 1 | NIH | 5/5/2026 | $1,061,520 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21AI196804 | Ex-Vivo Machine Perfusion To Promote Tolerance Induction in Deceased Donor Kidney Transplantation | 000 | 1 | NIH | 2/23/2026 | $416,622 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21AI196488 | The GI tract in Systemic Alloimmunity | 000 | 1 | NIH | 2/6/2026 | $436,454 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R00HL169733 | Whole genome sequence interpretation for lipids to discover new genes and mechanisms for coronary artery disease | 000 | 3 | NIH | 4/2/2026 | $249,000 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21HL184268 | Using sleep EEG for tracking longitudinal changes in brain state and waketime cognitive function | 000 | 1 | NIH | 5/1/2026 | $266,541 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AI195674 | Decoding the neuroimmune control of cutaneous gamma/delta cell function in allergic immunity | 000 | 1 | NIH | 2/9/2026 | $776,034 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01DA061887 | Evaluation of Community Health Worker Support to Improve Tobacco Use Disorder Outcomes in Medicaid Beneficiaries with Serious Mental Illness | 000 | 1 | NIH | 5/4/2026 | $740,451 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R03DK145781 | Audible diabetesRx: An audio-based digital tool to address health literacy barriers to medication adherence in type 2 diabetes | 000 | 1 | NIH | 2/4/2026 | $123,750 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21AG096539 | ROOTS: Revealing cognitive Outcomes in 'zeroth gen' Older immigranTS | 000 | 1 | NIH | 2/3/2026 | $453,750 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01DA062848 | Genomic Tests for Substance Use Disorders in Clinical Care: Examining Challenges and Opportunities | 000 | 1 | NIH | 2/26/2026 | $769,268 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01DK145735 | Interrogating the role of H3K4 & H3K27 methylation in hematopoiesis with novel histone tools | 000 | 1 | NIH | 3/2/2026 | $761,577 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01MH139643 | Characterizing intracortical feedforward and feedback sensory processes in ASD | 000 | 1 | NIH | 3/27/2026 | $824,728 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21DE034917 | Photochemical Tissue Passivation (PTP) to Reduce Temporomandibular Joint (TMJ) Osteoarthritis (OA) | 000 | 1 | NIH | 2/13/2026 | $408,951 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG093756 | Multi-biomarker evaluation of 64Cu-FBP8 PET for imaging of brain fibrin in aging and neurodegeneration | 000 | 1 | NIH | 2/17/2026 | $684,567 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21DA064871 | Next generation PET neuroimaging for safe, accessible measurement of opioid addiction neurobiology | 000 | 1 | NIH | 5/5/2026 | $451,670 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01NS146113 | Non-Invasive Vagus Nerve Stimulation in Subarachnoid Hemorrhage | 000 | 1 | NIH | 1/21/2026 | $511,402 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HL166342 | Indexed Exercise Blood Pressure and Its Relationship with Adverse Vascular and Ventricular Remodeling | 000 | 1 | NIH | 5/4/2026 | $614,843 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AI192313 | A tissue-based approach to understanding TB-associated lung fibrosis | 000 | 1 | NIH | 2/3/2026 | $798,107 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01HL182914 | Effectiveness of Therapies for Heart Failure with Mildly Reduced Ejection Fraction | 000 | 1 | NIH | 5/4/2026 | $867,656 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01AG094861 | Understanding and targeting chromatin mechanisms of cytoplasmic chromatin fragments during senescence and aging | 000 | 1 | NIH | 4/29/2026 | $463,000 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R03DK145936 | Molecularly-informed polygenic scores for the prediction of response to omega-3 fatty acid supplementation | 000 | 1 | NIH | 5/25/2026 | $123,750 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K99MH144561 | Electrophysiological biomarkers to guide deep brain stimulation treatment in obsessive-compulsive disorder | 000 | 1 | NIH | 5/26/2026 | $129,195 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01MH137056 | R-loop-induced CGG contraction as a therapeutic approach for Fragile X syndrome | 000 | 1 | NIH | 5/28/2026 | $824,998 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21HD118634 | Enteric neurochemical plasticity and its modulation for future personalized treatment for enteric neuropathies | 000 | 1 | NIH | 5/27/2026 | $397,173 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21DA065889 | Precision Risk Modeling to Reduce Opioid Overdose Deaths among Individuals Experiencing Homelessness | 000 | 1 | NIH | 5/20/2026 | $476,808 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01CA315856 | Spatial control of synthetic immunogenic cytotoxicity for the treatment of locally advanced lung cancer | 000 | 1 | NIH | 6/8/2026 | $682,140 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21AI199818 | Harnessing lysosome trafficking for enhanced antigen presentation | 000 | 1 | NIH | 5/22/2026 | $228,462 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K08AR086316 | Unraveling shared and unique mechanisms of autoimmunity using systems immunology approaches: Regulatory T cell dysfunction in Lupus | 000 | 1 | NIH | 5/20/2026 | $165,240 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01DK146327 | BMP2/6 ligand formation and function in development and iron homeostasis | 000 | 1 | NIH | 1/26/2026 | $813,961 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R21NS145499 | Exercise Preconditioning and Compensatory Oligodendrogenesis in Subcortical Ischemic Vascular Dementia | 000 | 1 | NIH | 5/12/2026 | $439,150 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23DK143316 | Optimizing Glycemic Monitoring and Management in People with Type 2 Diabetes and Chronic Kidney Disease | 000 | 1 | NIH | 3/19/2026 | $197,320 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R00EB032749 | Wearable RF-EEG Cap for closed loop TMS/fMRI/EEG Applications | 000 | 4 | NIH | 6/3/2026 | $249,000 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K23AT013273 | Toolkit for Optimal Pain Management in the Emergency Department: A mind-body intervention for pain catastrophizing and pain anxiety among individuals with chronic pain in the Emergency Department | 000 | 1 | NIH | 4/17/2026 | $170,640 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01MH138281 | Electronic Partner Notification for STIs: A Syndemic Approach to Improve HIV and STI Service Access in MA | 000 | 1 | NIH | 3/19/2026 | $855,983 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K01DK146206 | c-Kit receptor signaling in the modulation of collecting duct function | 000 | 1 | NIH | 3/19/2026 | $110,865 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K01DK146206 | c-Kit receptor signaling in the modulation of collecting duct function | 001 | 1 | NIH | 5/14/2026 | $29,896 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R03DA064903 | Uncovering Patterns in the Evolving Drug Supply to Detect Emerging Overdose Trends Using Machine Learning | 001 | 1 | NIH | 4/3/2026 | -$62,000 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R03DA064903 | Uncovering Patterns in the Evolving Drug Supply to Detect Emerging Overdose Trends Using Machine Learning | 000 | 1 | NIH | 3/9/2026 | $330,000 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | R01DK146964 | GPAT2 REGULATES MINERAL METABOLISM IN KIDNEY DISEASE | 000 | 1 | NIH | 4/8/2026 | $622,959 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K99AR084551 | Non-canonical transcriptional activation of MITF in pigment cells. | 000 | 1 | NIH | 4/8/2026 | $107,784 |
| | 2026 | 2026 | THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST | BOSTON | MA | 02114-2621 | SUFFOLK | USA | K08MH141190 | Uncertainty-Aware Prediction of Differential Responses to Antidepressants: Leveraging EHR and Genomics | 000 | 1 | NIH | 4/17/2026 | $790,560 |
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