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Infectious Disease/Basic Microbial Pathogenic Mechanisms

Award Number: T32AI007172
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 09/15/1980
PERIOD OF PERFORMANCE END DATE: 06/30/2026

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Infectious Disease/Basic Microbial Pathogenic Mechanisms - PROJECT ABSTRACT This is an application to renew the Infectious Diseases/Basic Microbial Pathogenesis Training Grant from Washington University. With the advent of generally available antibiotic therapy about 50 years ago, many physicians and scientists predicted the end of infectious diseases as a major area of health concern. Subsequent events have proven this prediction wrong, and the past decades have seen the emergence of many newly identified infectious diseases, including Lyme Disease, erlichiosis, SARS, COVID-19, West Nile encephalitis, chikungunya, MERS, ebola and HIV. The reemergence of old infectious diseases, such as malaria and tuberculosis, in more virulent and more antibiotic resistant forms also has increased public attention on the health problems posed by infectious diseases. It is rare that a week goes by without some troubling headline concerning new infectious disease outbreaks. Thus, far from gradual disappearance as a health concern, infectious diseases have emerged as being of increasing importance to the health concerns of the nation. The emerging antibiotic resistance of current pathogens and the rise of new disease agents have made clear the necessity of increased fundamental scientific investigation into all aspects of infectious diseases. The purpose of the Washington University Training Program in Infectious Diseases/Basic Microbial Pathogenesis is to help fulfill this need by recruiting promising young investigators to this field and training them in outstanding research programs with preeminent investigators who collaborate across multiple disciplines (or who function in interdisciplinary teams) to perform infectious disease research. Our Training Program, which has had NIH support for the past 40 years, integrates faculty from four departments: Medicine, Pediatrics, Molecular Microbiology and Pathology & Immunology. The program provides training to M.D., Ph.D., and M.D./Ph.D. postdoctoral fellows, and to Ph.D. and M.D./Ph.D. students, in disciplines related to pathogenesis and host defense in Infectious Diseases. The laboratories of the program preceptors use tools of molecular biology, biochemistry, genetics, genomics, immunology, cell biology and translational medicine. Thus, the program trains young investigators to be able to answer the important questions of microbial pathogenesis, from studies of basic biology through application to the bedside.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $573,038 )
2025	2025	WASHINGTON UNIVERSITY, THE	1 BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Allergy and Infectious Diseases Research	000	45	5/14/2025	NON-COMPETING CONTINUATION	$573,038
														Subtotal = $573,038

Issue Date FY: 2024 ( Subtotal = $581,385 )
2024	2024	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63110	SAINT LOUIS CITY	USA	Allergy and Infectious Diseases Research	000	44	5/24/2024	NON-COMPETING CONTINUATION	$581,385
														Subtotal = $581,385

Issue Date FY: 2023 ( Subtotal = $566,528 )
2023	2023	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Allergy and Infectious Diseases Research	001	43	5/12/2023	NON-COMPETING CONTINUATION	$566,244
2023	2020	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63110	SAINT LOUIS CITY	USA	Allergy and Infectious Diseases Research	000	40	11/23/2022	NON-COMPETING CONTINUATION	$284
														Subtotal = $566,528

Issue Date FY: 2022 ( Subtotal = $585,190 )
2022	2022	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Allergy and Infectious Diseases Research	005	42	5/25/2022	NON-COMPETING CONTINUATION	-$3
2022	2022	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Allergy and Infectious Diseases Research	002	42	4/28/2022	NON-COMPETING CONTINUATION	$585,193
2022	2021	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Allergy and Infectious Diseases Research	004	41	5/17/2022	COMPETING CONTINUATION	$284
2022	2021	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Allergy and Infectious Diseases Research	001	41	4/4/2022	COMPETING CONTINUATION	$255,949
2022	2020	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Allergy and Infectious Diseases Research	000	40	4/4/2022	NON-COMPETING CONTINUATION	-$255,949
2022	2020	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Allergy and Infectious Diseases Research	003	40	5/17/2022	NON-COMPETING CONTINUATION	-$284
														Subtotal = $585,190

Issue Date FY: 2021 ( Subtotal = $548,481 )
2021	2021	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Allergy and Infectious Diseases Research	000	41	6/10/2021	COMPETING CONTINUATION	$548,481
														Subtotal = $548,481

Issue Date FY: 2020 ( Subtotal = $567,470 )
2020	2020	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Allergy and Infectious Diseases Research	000	40	4/16/2020	NON-COMPETING CONTINUATION	$567,470
														Subtotal = $567,470

Issue Date FY: 2019 ( Subtotal = $508,535 )
2019	2019	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Allergy and Infectious Diseases Research	000	39	5/1/2019	NON-COMPETING CONTINUATION	$508,535
														Subtotal = $508,535

Issue Date FY: 2018 ( Subtotal = $613,556 )
2018	2018	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Allergy and Infectious Diseases Research	000	38	5/25/2018	NON-COMPETING CONTINUATION	$613,556
														Subtotal = $613,556

Issue Date FY: 2017 ( Subtotal = $558,388 )
2017	2017	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Allergy and Infectious Diseases Research	003	37	7/12/2017	NON-COMPETING CONTINUATION	$3,033
2017	2017	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Allergy and Infectious Diseases Research	002	37	5/26/2017	NON-COMPETING CONTINUATION	$555,355
2017	2016	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Allergy and Infectious Diseases Research	001	36	12/2/2016	COMPETING CONTINUATION	$205,502
2017	2014	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Allergy and Infectious Diseases Research	000	35	12/2/2016	NON-COMPETING CONTINUATION	-$205,502
														Subtotal = $558,388

Issue Date FY: 2016 ( Subtotal = $588,918 )
2016	2016	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Allergy and Infectious Diseases Research	000	36	7/8/2016	COMPETING CONTINUATION	$588,918
2016	2016	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	631121408	SAINT LOUIS CITY	USA	Allergy and Infectious Diseases Research	002	36	7/19/2016	COMPETING CONTINUATION	$0
2016	2014	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	631121408	SAINT LOUIS CITY	USA	Allergy and Infectious Diseases Research	001	35	7/19/2016	NON-COMPETING CONTINUATION	$0
														Subtotal = $588,918

Issue Date FY: 2014 ( Subtotal = $540,710 )
2014	2014	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Allergy and Infectious Diseases Research	000	35	6/17/2014	NON-COMPETING CONTINUATION	$540,710
														Subtotal = $540,710

Issue Date FY: 2013 ( Subtotal = $629,751 )
2013	2013	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Allergy and Infectious Diseases Research	000	34	5/20/2013	NON-COMPETING CONTINUATION	$629,751
														Subtotal = $629,751

Issue Date FY: 2012 ( Subtotal = $622,090 )
2012	2012	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Allergy and Infectious Diseases Research	000	33	6/13/2012	NON-COMPETING CONTINUATION	$622,090
														Subtotal = $622,090

Issue Date FY: 2011 ( Subtotal = $613,577 )
2011	2011	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Allergy and Infectious Diseases Research	000	32	8/12/2011	NON-COMPETING CONTINUATION	$613,577
														Subtotal = $613,577

Issue Date FY: 2010 ( Subtotal = $613,480 )
2010	2010	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Allergy and Infectious Diseases Research	000	31	7/19/2010	COMPETING CONTINUATION	$613,480
														Subtotal = $613,480

Issue Date FY: 2009 ( Subtotal = $493,633 )
2009	2009	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Allergy and Infectious Diseases Research	000	30	7/13/2009	NON-COMPETING CONTINUATION	$493,633
														Subtotal = $493,633

Issue Date FY: 2008 ( Subtotal = $489,947 )
2008	2008	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Allergy and Infectious Diseases Research	000	29	7/30/2008	NON-COMPETING CONTINUATION	$489,947
														Subtotal = $489,947

Issue Date FY: 2007 ( Subtotal = $488,146 )
2007	2007	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Allergy and Infectious Diseases Research	000	28	8/28/2007	NON-COMPETING CONTINUATION	$488,146
														Subtotal = $488,146

Issue Date FY: 2006 ( Subtotal = $279,388 )
2006	2006	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Allergy and Infectious Diseases Research	000	27	8/8/2006	NON-COMPETING CONTINUATION	$279,388
														Subtotal = $279,388

Issue Date FY: 2005 ( Subtotal = $378,162 ) (Continued on the next page)
Grand Total All Awards = $13,759,169

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Infectious Disease/Basic Microbial Pathogenic Mechanisms

Award Number: T32AI007172

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 09/15/1980

PERIOD OF PERFORMANCE END DATE: 06/30/2026

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