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SCIEX 4000 QTRAP MASS SPECTROMETER

Award Number: S10RR024563
ORGANIZATION: NATIONAL CENTER FOR RESEARCH RESOURCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 02/15/2008
PERIOD OF PERFORMANCE END DATE: 02/14/2009

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SCIEX 4000 QTRAP MASS SPECTROMETER - DESCRIPTION (provided by applicant): This is a new application requesting funds to support the acquisition of a SCIEX 4000 QTRAP mass spectrometer to enhance the function of the Lipid Analytic Core Lab at MUSC. This core lab has been in operation for 5 years, and has continually developed novel methodology and progressively advanced the application of LC/MS for the determination of lipids and standardized quantitation. It has been critical to the successful funding of two NIH program project grants (on sphingolipids in cancer at MUSC and apoptosis in liver cells at a collaborating institution), an NIH/NCRR Center of Biomedical Research Excellence (initial and competing renewal grants), and multiple individual investigator research projects as a core facility of the Hollings Cancer Center at MUSC. In 2006, the Lipid Analytic Core Lab logged more than 11,500 lipid assays for 23 MUSC users, 17 users outside MUSC, and 5 international users. The core lab currently relies on two LC/MS set ups ---- both are being used to capacity. One has been in service more than 14 years, has passed its normal life expectancy, and is no longer supported by the manufacturer. Therefore, a core group of 17 major users, representing 7 departments at MUSC, are requesting this grant to acquire a SCIEX 4000 QTRAP mass spectrometer in configuration with a dedicated HPLC for sample delivery and component separation. This request is supported by a representative sample of 7 outside users at premier biomedical research institutions across the nation. Technical expertise within the Analytic Core Lab includes a fulltime faculty member with extensive qualitative and quantitative lipid chemistry and 3 staff members. A comprehensive Administrative Plan ensures appropriate management, oversight, equitable access, and compliance. Strong institutional commitment ensures long term operation and maintenance of the requested instrument and overall facility.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2008 ( Subtotal = $385,401 )
2008	2008	MEDICAL UNIVERSITY OF SOUTH CAROLINA	19 HAGOOD AVE, SUITE 608	CHARLESTON	SC	29425	CHARLESTON	USA	National Center for Research Resources	000	1	2/15/2008	NEW	$385,401
														Subtotal = $385,401

Grand Total All Awards = $385,401

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SCIEX 4000 QTRAP MASS SPECTROMETER

Award Number: S10RR024563

ORGANIZATION: NATIONAL CENTER FOR RESEARCH RESOURCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 02/15/2008

PERIOD OF PERFORMANCE END DATE: 02/14/2009

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