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BD FACSDiscover S8 Cell Sorter with Image-Based and Spectral Sorting Capabilities for Biomedical Research

Award Number: S10OD040288
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 06/15/2026
PERIOD OF PERFORMANCE END DATE: 06/14/2027

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BD FACSDiscover S8 Cell Sorter with Image-Based and Spectral Sorting Capabilities for Biomedical Research - Project Summary. We request a BD FACSDiscover S8 Cell Sorter to bring advanced image-based and spectral sorting capabilities to UCLA, enabling high-throughput analysis and isolation of cells based on spatial features, intracellular localization, and cell-cell interactions—capabilities not possible with conventional flow cytometers. Housed in the Broad Stem Cell Research Center and supported by the David Geffen School of Medicine, the instrument will serve NIH-funded investigators across fields including immunology, oncology, developmental biology, and biomedical engineering. The S8’s real- time imaging enables sorting of nanovial compartments based on direct tumor–immune cell contact, spatial RNA localization such as XIST nuclear foci, or the presence of phase-separated RNA droplets in live cells. Its spectral flow cytometry allows flexible, high-parameter panels for identifying rare hematopoietic stem cell subsets, profiling nanoparticle uptake, and assessing complex immune activation signatures without extensive compensation. These features directly support cutting-edge projects such as nanovial-enabled T cell functional screening and sorting based on secreted cytokines, growth or reporter activation. Together, these capabilities will allow researchers to interrogate rare and dynamic cell states with unprecedented precision, advancing efforts to understand and treat cancer, autoimmune diseases, infections, developmental disorders, and enabling next-generation gene and cell therapies.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $703,181 )
2026	2026	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Research Infrastructure Programs	000	1	6/9/2026	NEW	$703,181
														Subtotal = $703,181

Grand Total All Awards = $703,181

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BD FACSDiscover S8 Cell Sorter with Image-Based and Spectral Sorting Capabilities for Biomedical Research

Award Number: S10OD040288

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 06/15/2026

PERIOD OF PERFORMANCE END DATE: 06/14/2027

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