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Acquisition of a surface plasmon resonance instrument for research and teaching

Award Number: S10GM164892
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/15/2026
PERIOD OF PERFORMANCE END DATE: 07/14/2027

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Acquisition of a surface plasmon resonance instrument for research and teaching - PROJECT SUMMARY/ABSTRACT The instrument requested in this NIH Instrumentation for Resource-Limited Institutions (RLI-S10) grant application is a Nicoya OpenSPR-XT surface plasmon resonance (SPR) instrument that will greatly enhance the research and teaching of many investigators and faculty at University of Missouri-St. Louis (UMSL). While principal investigators and teaching labs at UMSL are already involved in a variety of basic biomedical and chemistry/biology/biochemical experimentation, this platform and technology will be new on campus. The ability to directly assess binding and kinetics with the OpenSPR-XT instrument will further strengthen numerous research projects and provide excellent exposure to students populating UMSL biochemistry, chemistry and biology advanced teaching labs. The OpenSPR-XT is the world’s first benchtop SPR instrument with the ability to carry out real-time, label-free analysis of affinity and kinetics data for a wide range of molecular applications. The system is user-friendly and adapts to any skill level with no need for a dedicated technician for real-time monitoring of binding. Basic biomedical research at UMSL is carried out by primarily graduate and undergraduate students and the addition of SPR capability will allow direct and accurate binding measurements for a wide variety of molecular interactions. The integration of this technology into our upper level and graduate lab courses will benefit our students as they transition to industry or further their research training in an advanced degree program. This grant proposal describes numerous UMSL research objectives and teaching applications that will benefit substantially from the OpenSPR-XT instrument acquisition. The technology is quite versatile, accommodating many different types of interactions different researcher needs in multiple disciplines in biology, biochemistry, chemistry, plant science, and biophysics. The RLI-S10 grant mechanism is ideal for UMSL, as lab space, instrument management, and researcher interest are all readily available to accommodate the instrument addition.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $124,978 )
2026	2026	UNIVERSITY OF MISSOURI SYSTEM	1 UNIVERSITY BLVD	SAINT LOUIS	MO	63121	SAINT LOUIS	USA	Biomedical Research and Research Training	000	1	7/10/2026	NEW	$124,978
														Subtotal = $124,978

Grand Total All Awards = $124,978

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Acquisition of a surface plasmon resonance instrument for research and teaching

Award Number: S10GM164892

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/15/2026

PERIOD OF PERFORMANCE END DATE: 07/14/2027

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