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RLI-S10 Instrumentation Grant: Acquisition of hypoxic chamber that creates a comprehensive range of oxygen levels

Award Number: S10GM164680
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/01/2026
PERIOD OF PERFORMANCE END DATE: 06/30/2027

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RLI-S10 Instrumentation Grant: Acquisition of hypoxic chamber that creates a comprehensive range of oxygen levels - Project Summary: We request the purchase of a HypOxystation H35 to be housed at the School of Natural and Behavioral Science (SNBS), Biology Department at Brooklyn College (BC), City University of New York (CUNY). Brooklyn College is a PUI (primarily undergraduate institution) with substantial limited NIH research funding. Even so, faculty at SNBS are actively engaged in multi-disciplinary research projects where PhD students and undergraduates, amongst others get practical training in scientific research. With the recognition of the BCCC-CURE (Brooklyn College Cancer Center), in 2020, we have witnessed significant inter-disciplinary research expansion at the College. Many of our faculty research include studying mechanisms involved in tumorigenesis and/or other pathological conditions or focused on developing novel therapeutics to target such diseases. An important component in the ongoing projects is to understand how differential oxygen tensions impact biological outcome. Scientists from different departments including biology, chemistry & biochemistry, earth and environmental sciences, and health and nutrition, will have an ability to control precise oxygen level in each experimental setting with HypOxystation H35. The various research projects encompass studying the control of hypoxia-induced gene expression in tumorigenesis, angiogenesis and metastasis; role of methyl nutrients and polyunsaturated fatty acid into regulate prenatal programing of pathophysiology of Non-alcoholic Steatohepatitis (NASH), geochemical processes under redox-sensitive environments as well as mechanistic organic photochemistry in toxicity priming. Additionally, our microbiology laboratory course includes urban microbiome project, yet, we have very limited and sub-optimal approaches to grow facultative anaerobes. The purchase of HypOxystation H35 will not only benefit researchers but also expose the next generation scientists to this mid-to-high-end equipment for an experiential learning. The plan to house this equipment in a biology space with an independent door will enable all the users and potential new users to efficiently access the equipment to perform their tasks. At BC and even at CUNY, we do not have access to such an instrument and acquisition of H35 will enhance the overall research and educational capacity of the college.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $182,706 )
2026	2026	RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK	2900 BEDFORD AVE	BROOKLYN	NY	11210	KINGS	USA	Biomedical Research and Research Training	000	1	6/23/2026	NEW	$182,706
														Subtotal = $182,706

Grand Total All Awards = $182,706

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RLI-S10 Instrumentation Grant: Acquisition of hypoxic chamber that creates a comprehensive range of oxygen levels

Award Number: S10GM164680

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/01/2026

PERIOD OF PERFORMANCE END DATE: 06/30/2027

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