Monday, November 17, 2025 11/17/2025

The GCE4All Center: Unleashing the Potential of Genetic Code Expansion for Biomedical Research

Award Number: RM1GM144227
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 02/01/2022
PERIOD OF PERFORMANCE END DATE: 01/31/2027

Group Awards By:

View Award Description

The GCE4All Center: Unleashing the Potential of Genetic Code Expansion for Biomedical Research - EQUIPMENT SUPPLEMENT ABSTRACT The GCE4All Biomedical Technology Optimization and Dissemination Center at Oregon State University (OSU) serves to optimize, develop, and broadly disseminate Genetic Code Expansion (GCE) technology – the engineering of cellular translation to express proteins containing non-canonical amino acids (ncAAs). During its envisioned lifespan of ≤15 years, the Center's mission is to effectively extend existing GCE technologies for facile use by non-specialists, and to broadly disseminate them via widespread education, effective training, and by providing sustainable access to optimized technologies via established repositories – enabling powerful GCE approaches to become standard, widely-used tools of biomedical researchers. As we optimize our GCE technology, we require frequent and dependable access to a cell sorter for separating cells containing a range of functionally evolved or genome encoded translational components. However, the only cell sorter currently at OSU is across campus from our building, owned by a different College, and is over 8 years old with no service contract in place or staff in charge of routine upkeep. These challenges lead to limitations in access and functionality that often disrupt our workflows. Here, we request funds to acquire a Sony MA900, a multi- application benchtop cell sorter. This would allow us a center housed system that is walk-up capable for use on our samples, samples from our DBP collaborations, and samples from our yearly workshop attendees. A permanent center staff member will be assigned to equipment maintenance and user training. The in-house ability to run and process our own samples on a daily basis will greatly accelerate the center mission regarding GCE technology development, optimization and dissemination for DBPs and GCE trainees. The summary of our original grant is included in our research strategy document.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $1,503,381 )
2025	2025	OREGON STATE UNIVERSITY	1500 SW JEFFERSON AVE	CORVALLIS	OR	97331	BENTON	USA	Biomedical Research and Research Training	001	4	8/15/2025	NON-COMPETING CONTINUATION	$111,374
2025	2025	OREGON STATE UNIVERSITY	1500 SW JEFFERSON AVE	CORVALLIS	OR	97331	BENTON	USA	Biomedical Research and Research Training	002	4	8/22/2025	SUPPLEMENT FOR EXPANSION	$389,631
2025	2025	OREGON STATE UNIVERSITY	1500 SW JEFFERSON AVE	CORVALLIS	OR	97331	BENTON	USA	Biomedical Research and Research Training	000	4	1/28/2025	NON-COMPETING CONTINUATION	$1,002,376
														Subtotal = $1,503,381

Issue Date FY: 2024 ( Subtotal = $1,113,750 )
2024	2024	OREGON STATE UNIVERSITY	1500 SW JEFFERSON AVE	CORVALLIS	OR	97331	BENTON	USA	Biomedical Research and Research Training	002	3	9/13/2024	NON-COMPETING CONTINUATION	$0
2024	2024	OREGON STATE UNIVERSITY	1500 SW JEFFERSON AVE	CORVALLIS	OR	97331	BENTON	USA	Biomedical Research and Research Training	001	3	7/29/2024	NON-COMPETING CONTINUATION	$111,374
2024	2024	OREGON STATE UNIVERSITY	1500 SW JEFFERSON AVE	CORVALLIS	OR	97331	BENTON	USA	Biomedical Research and Research Training	000	3	1/17/2024	NON-COMPETING CONTINUATION	$1,002,376
														Subtotal = $1,113,750

Issue Date FY: 2023 ( Subtotal = $1,363,705 )
2023	2023	OREGON STATE UNIVERSITY	1500 SW JEFFERSON ST	CORVALLIS	OR	97331	BENTON	USA	Biomedical Research and Research Training	003	2	7/25/2023	NON-COMPETING CONTINUATION	$0
2023	2023	OREGON STATE UNIVERSITY	1500 SW JEFFERSON ST	CORVALLIS	OR	97331	BENTON	USA	Biomedical Research and Research Training	002	2	5/22/2023	SUPPLEMENT FOR EXPANSION	$249,955
2023	2023	OREGON STATE UNIVERSITY	1500 SW JEFFERSON ST	CORVALLIS	OR	97331	BENTON	USA	Biomedical Research and Research Training	001	2	4/5/2023	NON-COMPETING CONTINUATION	$111,374
2023	2023	OREGON STATE UNIVERSITY	1500 SW JEFFERSON ST	CORVALLIS	OR	97331	BENTON	USA	Biomedical Research and Research Training	000	2	1/24/2023	NON-COMPETING CONTINUATION	$1,002,376
														Subtotal = $1,363,705

Issue Date FY: 2022 ( Subtotal = $1,113,750 )
2022	2022	OREGON STATE UNIVERSITY	1500 SW JEFFERSON ST	CORVALLIS	OR	97331	BENTON	USA	Biomedical Research and Research Training	000	1	1/31/2022	NEW	$1,113,750
														Subtotal = $1,113,750

Grand Total All Awards = $5,094,586

Top

All Categories

About

Search

Reports

Data Submission

Award Information

The GCE4All Center: Unleashing the Potential of Genetic Code Expansion for Biomedical Research

Award Number: RM1GM144227

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 02/01/2022

PERIOD OF PERFORMANCE END DATE: 01/31/2027

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer