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Prevalence, etiology, and clinical implications of low count monoclonal B-cell lymphocytosis (MBL)

Award Number: RF1AG058266
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/01/2018
PERIOD OF PERFORMANCE END DATE: 08/31/2029

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Prevalence, etiology, and clinical implications of low count monoclonal B-cell lymphocytosis (MBL) - Monoclonal B-cell lymphocytosis (MBL) is one of the most common malignant precursor conditions, affecting 8-10 million adults >40 years of age in the United States. MBL is defined by the presence of a clonal B-cell population in the blood with sub-classification based on the immunophenotype of the cell surface markers and the size of the B-cell clone: low-count MBL (LCMBL) is defined as clonal B-cell count <0.5 x109 cells/L and high-count MBL (HCMBL) as clonal B-cell count between 0.5 and 5x109/L. Of clinical and


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $3,354,111 )
2025	2025	MAYO CLINIC	200 1ST ST SW	ROCHESTER	MN	55905	OLMSTED	USA	Aging Research	000	6	8/15/2025	COMPETING CONTINUATION	$3,354,111
														Subtotal = $3,354,111

Grand Total All Awards = $3,354,111

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Prevalence, etiology, and clinical implications of low count monoclonal B-cell lymphocytosis (MBL)

Award Number: RF1AG058266

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/01/2018

PERIOD OF PERFORMANCE END DATE: 08/31/2029

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