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 | Issue Date FY: 2026 ( Subtotal = $210,597,691 ) (Continued on the next page) |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AG097480 | Role of Brd4 in enhancing old donor heart preservation quality via 3D chromosomal restructuring | 000 | 1 | NIH | 1/28/2026 | $660,157 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK145433 | Acute Kidney Injury in Care Transitions: The ACT Pragmatic Trial | 000 | 1 | NIH | 3/3/2026 | $796,370 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01CA316533 | Therapy-induced senescence as a driver of immune activation and myeloid plasticity in multiple myeloma | 000 | 1 | NIH | 7/20/2026 | $387,713 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R21AG101515 | Time-Efficient Inspiratory Muscle Strength Training for Reducing Sympathetic Activity and Improving Sleep in Midlife Women | 000 | 1 | NIH | 6/16/2026 | $439,258 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01NS142427 | Acute and Chronic Repercussions of Spinal Cord Stimulation following Spinal Cord Injury | 000 | 1 | NIH | 7/20/2026 | $622,784 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R21AI200456 | “Targeting Phosphoglucomutase in Pneumocystis Pneumonia” | 000 | 1 | NIH | 7/13/2026 | $441,100 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01CA307402 | Addressing Thyroid Cancer Overdiagnosis: AI-Driven Identification, Characterization, and Outcomes of Incidental Thyroid Nodules | 000 | 1 | NIH | 3/13/2026 | $676,067 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK145458 | Ultrasound Imaging Biomarkers of Crohn's Disease | 000 | 1 | NIH | 7/28/2026 | $694,443 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AI195557 | Understanding iPSC reprogramming using single cycle Measles vector | 000 | 1 | NIH | 7/14/2026 | $795,316 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK144208 | Discovering ADPKD Modifier Genes and Mechanisms via Zebrafish Genetics | 000 | 1 | NIH | 7/28/2026 | $748,694 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R21AG097887 | Real world impact of glucagon-like peptide receptor agonist (GLP-1 RA) use on older adults | 000 | 1 | NIH | 3/13/2026 | $443,850 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL185686 | HOPE: Advancing HFpEF Management Through Evidence-based Treatment Optimization and Outcome Prediction | 000 | 1 | NIH | 7/30/2026 | $801,170 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | U01CA299909 | Prospective Detection and Monitoring of NF1 peripheral nerve sheath tumors using cell-free DNA | 000 | 1 | NIH | 6/11/2026 | $688,661 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AG094714 | Impact of menopause on blood pressure regulation during exercise | 000 | 1 | NIH | 8/4/2026 | $678,987 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL176479 | Quantitative and longitudinal assessment of diffuse pulmonary parenchymal disease using lung ultrasound surface wave elastography | 001 | 1 | NIH | 7/2/2026 | -$661,884 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL176479 | Quantitative and longitudinal assessment of diffuse pulmonary parenchymal disease using lung ultrasound surface wave elastography | 001 | 1 | NIH | 7/2/2026 | $661,884 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL176479 | Quantitative and longitudinal assessment of diffuse pulmonary parenchymal disease using lung ultrasound surface wave elastography | 000 | 1 | NIH | 6/25/2026 | $661,884 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01CA315861 | Individualized DNA junctions for glioma response assessment via longitudinal liquid biopsies | 000 | 1 | NIH | 7/24/2026 | $565,423 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | K23MD019644 | Screening Mammography: Early Breast Cancer Detection for All at Risk | 000 | 3 | NIH | 4/17/2026 | $155,520 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01NS144593 | Antibody Drug Conjugate Designs to Enhance the Therapeutic Window for Brain Tumors | 000 | 2 | NIH | 5/11/2026 | $620,652 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | OT2OD039849 | All of Us Biobank | 001 | 1 | NIH | 7/14/2026 | $13,200,000 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL176555 | Discovering aging-associated genetic modifiers and therapies for anthracycline-induced cardiotoxicity | 001 | 2 | NIH | 5/19/2026 | $659,717 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | K23DK141902 | Choosing the Right BPH Procedure: Evaluating Patient Priorities and the Impact of Cost on BPH Surgical Preference | 000 | 2 | NIH | 7/6/2026 | $202,110 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AG081584 | Biophysically inspired mechanical biomarkers of normal pressure hydrocephalus | 000 | 3 | NIH | 2/23/2026 | $403,500 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | F32DK145067 | The role of sympathetic signaling in inflammation-induced colon dysfunction and recovery | 000 | 2 | NIH | 7/27/2026 | $79,348 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | U10CA180882 | Alliance Statistics and Data Management Center | 000 | 12 | NIH | 6/12/2026 | $8,830,288 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL164416 | Targeting Immune-Responsive Gene 1 (Irg1) and Itaconate for Cardioprotection of the Donor Heart for Transplantation | 000 | 5 | NIH | 7/16/2026 | $630,628 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK137231 | Engineering microcapsules for scalable differentiation of human pluripotent stem cells into hepatocytes | 000 | 3 | NIH | 2/13/2026 | $555,713 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01EB036541 | A Dynamic Patient Data Library and Virtual Imaging Trial Platform for Training and Evaluating AI-based Algorithms in CT Imaging | 000 | 2 | NIH | 6/8/2026 | $635,898 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AI108889 | Mechanisms of allostery and molecular recognition in efflux pumps | 003 | 13 | NIH | 6/19/2026 | $541,196 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R37CA302677 | Radiation synthetic combinations in high-risk Ewing sarcoma | 000 | 1 | NIH | 5/22/2026 | $659,028 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | UH3NS132128 | Hybrid approach for comprehensive mutation detection in a cell | 000 | 4 | NIH | 4/2/2026 | $562,212 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | F31CA301512 | Exploring LMTK2: A novel mediator of endocrine sensitivity in ER+ breast cancer | 001 | 1 | NIH | 4/9/2026 | $0 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | F31CA301512 | Exploring LMTK2: A novel mediator of endocrine sensitivity in ER+ breast cancer | 000 | 1 | NIH | 4/9/2026 | $50,114 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AA031167 | Multi-site DBS with precise timing control focusing on synaptic plasticity | 000 | 2 | NIH | 6/30/2026 | $543,111 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | UH3NS123066 | Optimizing Pharmacotherapy with Noninvasive Wearable Sensors and Subscalp EEG | 000 | 4 | NIH | 8/4/2026 | $699,582 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | U01CA308978 | The Lymphoma Epidemiology of Outcomes (LEO) Cohort Study | 000 | 1 | NIH | 3/9/2026 | $1,264,356 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01LM014760 | Virtual World-based Cardiac Rehabilitation to Promote Data-Powered Cardiovascular Health Among Cardiac Patients: A Multicenter Randomized Clinical Trial | 000 | 2 | NIH | 7/21/2026 | $373,996 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01CA313650 | Accelerated Biological Aging and Immunosenescence as Drivers for Racial Disparities in Monoclonal Gammopathy of Undetermined Significance (MGUS) | 000 | 1 | NIH | 5/8/2026 | $558,016 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | K08AA032553 | Multimodal Approach for Diagnosis and Prognosis of Metabolic and Alcohol-Associated Steatotic Liver Diseases | 000 | 2 | NIH | 8/3/2026 | $202,176 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R21CA302685 | Improving Treatment Sensitivity through Syk using Novel Translational Models of Uveal Melanoma | 000 | 1 | NIH | 5/14/2026 | $415,000 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01CA304910 | Regulation of Anti-Tumor Immunity by B7-H3 | 000 | 1 | NIH | 7/9/2026 | $651,290 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AI195565 | Regulation of target cell survival by TBK1 and IKKe | 000 | 1 | NIH | 2/23/2026 | $624,521 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | K23AR086105 | Upper respiratory-genetic and nasal microbiome risk factors for rheumatoid arthritis | 000 | 1 | NIH | 7/9/2026 | $175,176 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01MH143024 | SCH: Real-Time Engagement of Children for Individualizing Behavior Management with Wearables | 000 | 1 | NIH | 5/18/2026 | $301,092 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01CA300454 | Blood-based tumor and immune markers for risk stratification and monitoring treatment response in oligometastatic prostate cancer | 000 | 1 | NIH | 3/24/2026 | $667,710 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AI195606 | Establishing the etiology of chronic placental villitis of unknown etiology | 000 | 1 | NIH | 3/30/2026 | $689,081 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL184127 | Thrombolysis Resistance in Acute Ischemic Stroke | 000 | 1 | NIH | 8/6/2026 | $593,663 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | K08CA308863 | Unraveling the Mechanisms of Cyclin D1-Induced Replication Stress and DNA Damage Repair Dependencies in Mantle Cell Lymphoma: A Path to Novel Therapeutic Strategies for High-Risk Disease | 000 | 1 | NIH | 8/6/2026 | $324,272 |
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