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 | Issue Date FY: 2027 ( Subtotal = -$22,386 ) |
| | 2027 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AR076347 | The Role of Cellular Senescence in Carpal Tunnel Syndrome | 000 | 6 | NIH | 10/11/2026 | $0 |
| | 2027 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL160570 | Hydrogen Sulfide in Neonatal Airway Disease | 000 | 4 | NIH | 10/13/2026 | $0 |
| | 2027 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R21CA288898 | Evaluating Maintenance In Light chain Amyloidosis (EMILIA) | 000 | 2 | NIH | 10/8/2026 | $0 |
| | 2027 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R21AI188334 | Discovery of efflux pump inhibitors using a high-throughout bacterial assay | 000 | 2 | NIH | 10/8/2026 | $0 |
| | 2027 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01NS076491 | Computational and Biological Approach to Flow Diversion | 000 | 15 | NIH | 10/8/2026 | $0 |
| | 2027 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK129240 | Role of mitochondrial microRNAs (mitomiRs) in endogenous renal repair | 000 | 4 | NIH | 10/8/2026 | $0 |
| | 2027 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK059597 | Investigation of common disease mechanisms in nonsyndromic and syndromic PKD | 000 | 25 | NIH | 10/8/2026 | $0 |
| | 2027 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01GM144351 | Methods for microbiome compositional data | 000 | 5 | NIH | 10/21/2026 | $0 |
| | 2027 | 2025 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK130331 | Lipid metabolism and adipose tissue function | 000 | 4 | NIH | 10/26/2026 | $0 |
| | 2027 | 2025 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | F30MH131254 | Elucidating the neurochemical basis of LTP induction and maintenance in vivo | 000 | 4 | NIH | 10/27/2026 | -$8,100 |
| | 2027 | 2025 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | K25AG068368 | A patient-specific computational technique to predict spine injury risks associated with physical activities | 000 | 5 | NIH | 10/26/2026 | -$643 |
| | 2027 | 2024 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R56AI184121 | Pushing HIV-1 Vaccine Protection to the Mucosal Barrier | 000 | 1 | NIH | 10/21/2026 | -$13,643 |
|
| Issue Date FY: 2026 ( Subtotal = $321,536,663 ) (Continued on the next page) |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | UH3CA299358 | Assay Validation of Cell-free DNA Amplified DNA Junctions for High Grade Glioma Monitoring | 000 | 2 | NIH | 9/14/2026 | $402,746 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | U24HD121485 | Expanding the ClinGen Lysosomal Storage Disorder Curation Effort: VCEPs for Mucopolysaccharidosis Type II and IIIA | 000 | 1 | NIH | 9/23/2026 | $352,880 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01CA305931 | Radiomic phenotypes for invasive and advanced breast cancer | 000 | 1 | NIH | 5/7/2026 | $722,914 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AA031965 | Neurosteroids and Alcohol Use Disorder | 000 | 2 | NIH | 6/30/2026 | $700,490 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK142296 | Autophagic Processes and Hepatocellular Steatosis | 000 | 1 | NIH | 2/18/2026 | $495,130 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | UG3NS140118 | Augmenting immunotherapy pharmacodynamics in glioma | 000 | 1 | NIH | 9/11/2026 | $712,838 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | K99AG097974 | Brain degeneration and cognitive decline in patients with atypical Alzheimer's disease or suspected copathologies treated with amyloid-reducing therapies | 000 | 1 | NIH | 9/11/2026 | $132,057 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AG094841 | Prospective Evaluation of the Automated CAM-ICU-7: A Digital Marker for Delirium Severity in the ICU | 000 | 1 | NIH | 9/11/2026 | $835,279 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AR088008 | Redefining the Lifelong Natural History of Hip Osteoarthritis in Patients with Morphologic Abnormalities | 000 | 1 | NIH | 9/14/2026 | $607,990 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AG099961 | Metformin Beyond its Therapeutic Effect on Glucose Metabolism to Ameliorate Altered Brain Function and Cognition in People with Insulin Resistance | 000 | 1 | NIH | 9/7/2026 | $1,726,495 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R00AA030828 | Cortical-noradrenaline signaling in alcohol behavioral engagement | 000 | 3 | NIH | 9/7/2026 | $249,000 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R03NS148680 | Exploring the contribution of non-coding and somatic copy number variations to the Tourette Disorder | 000 | 1 | NIH | 9/17/2026 | $161,400 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AG103649 | Targeting PAR1 to overcome myelin deficits in aging and Alzheimer’s disease | 000 | 1 | NIH | 9/17/2026 | $662,808 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R56NS146584 | Determining electrophysiological and functional interactions between oral baclofen and spinal neuromodulation in humans with spinal cord injury. | 000 | 1 | NIH | 9/16/2026 | $550,273 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | K99AR086961 | Mapping PHLPP-Driven Mechanisms of Pain and Pathogenesis in Post-Traumatic Osteoarthritis | 000 | 1 | NIH | 9/9/2026 | $211,196 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL178855 | Effects of Sleep Restriction on Glycemic Control and Cardiovascular Risk Mechanisms in Type 1 Diabetes Mellitus | 000 | 1 | NIH | 9/17/2026 | $806,199 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AT014237 | CRCNS: Linking respiration and visual perception through brain-body integration | 000 | 1 | NIH | 9/1/2026 | $361,732 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | K08AA032553 | Multimodal Approach for Diagnosis and Prognosis of Metabolic and Alcohol-Associated Steatotic Liver Diseases | 000 | 2 | NIH | 8/3/2026 | $202,176 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R61NS150150 | Efflux-Aware Human BBB Assembloid Assay for Brain-Penetrant Therapeutic Discovery in Medulloblastoma | 000 | 1 | NIH | 9/16/2026 | $500,986 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | UG3CA315308 | Evaluation of a novel remote patient monitoring program for cancer patients initiating cancer-directed therapy: The SHIELD (Smart Health Integration for Early Life-saving Detection) | 000 | 1 | NIH | 9/16/2026 | $569,282 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | P50CA298941 | Mayo Clinic / University of Minnesota Prostate SPORE | 000 | 1 | NIH | 9/17/2026 | $2,235,791 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01CA317358 | Decoding response and toxicity to immune checkpoint inhibitors in lung cancer patients by noninvasive assessment of tumor microenvironment dynamics and circulating T cells | 000 | 1 | NIH | 9/10/2026 | $669,587 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | F31HD121285 | Impact of perinatal antibiotics on the generation of protective mammary IgA | 001 | 1 | NIH | 9/3/2026 | $0 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | F31HD121285 | Impact of perinatal antibiotics on the generation of protective mammary IgA | 000 | 1 | NIH | 9/3/2026 | $50,114 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AG097812 | Neurobiological Substrates of Falls in Cognitively Unimpaired Older Adults | 001 | 1 | NIH | 9/3/2026 | $0 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AG097812 | Neurobiological Substrates of Falls in Cognitively Unimpaired Older Adults | 000 | 1 | NIH | 9/2/2026 | $729,906 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK148623 | Mechanisms of Stem Cell Memory in the Intestinal Epithelium | 000 | 1 | NIH | 9/4/2026 | $688,220 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | F31HL188942 | LMNA Mutations: Mechanics and ROS in Cardiomyopathy | 000 | 1 | NIH | 9/4/2026 | $53,114 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R50CA305003 | Improving Patient Outcomes Through Subtype Specific NCI-Sponsored Sarcoma Clinical Trials | 000 | 1 | NIH | 9/4/2026 | $207,179 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AG102933 | Temporal Associations of Neuroinflammation with Alzheimer’s Disease Biomarkers and Cognition | 000 | 1 | NIH | 9/29/2026 | $677,880 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DA065510 | GLP-1 receptor agonists for the prevention and treatment of opioid use disorder | 000 | 1 | NIH | 9/10/2026 | $830,097 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R33HL177037 | Pragmatic trial of midodrine as a vasopressor-sparing agent in septic shock | 000 | 2 | NIH | 9/17/2026 | $789,678 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | UH3NS123066 | Optimizing Pharmacotherapy with Noninvasive Wearable Sensors and Subscalp EEG | 000 | 4 | NIH | 8/4/2026 | $699,582 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL174650 | A population-based study of deep learning measures of breast arterial calcification for improving women's health using repurposed mammogram images | 000 | 2 | NIH | 8/26/2026 | $712,396 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | UH3NS132128 | Hybrid approach for comprehensive mutation detection in a cell | 000 | 4 | NIH | 4/2/2026 | $562,212 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01LM014760 | Virtual World-based Cardiac Rehabilitation to Promote Data-Powered Cardiovascular Health Among Cardiac Patients: A Multicenter Randomized Clinical Trial | 000 | 2 | NIH | 7/21/2026 | $373,996 |
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