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 | Issue Date FY: 2026 ( Subtotal = $128,822,136 ) (Continued on the next page) |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R37CA276005 | Aak1 to increase infiltration of adoptively transferred cells into solid tumors | 001 | 4 | NIH | 4/16/2026 | $45,762 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R37CA276005 | Aak1 to increase infiltration of adoptively transferred cells into solid tumors | 000 | 4 | NIH | 1/27/2026 | $411,873 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | U01CA271014 | Impact of Genetic susceptibility along the continuum from MGUS to MM | 000 | 5 | NIH | 6/5/2026 | $617,059 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | K01DK140206 | Circadian regulation of molecular and systemic adipose tissue function in humans | 000 | 3 | NIH | 5/27/2026 | $172,022 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R21CA286349 | Characterization and treatment of a novel model of radiation optic neuropathy using the tree shrew | 000 | 3 | NIH | 3/26/2026 | $121,171 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | T32HL007111 | Cardiovasology | 001 | 47 | NIH | 6/8/2026 | $448,600 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL171056 | INTEGRATION OF MECHANICAL AND MOLECULAR CUES DURING DISTAL LUNG DEVELOPMENT | 001 | 3 | NIH | 3/25/2026 | $17,743 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL171056 | INTEGRATION OF MECHANICAL AND MOLECULAR CUES DURING DISTAL LUNG DEVELOPMENT | 000 | 3 | NIH | 3/6/2026 | $561,833 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK099160 | Molecular dissection of the ciliary gate | 000 | 12 | NIH | 12/15/2025 | $424,643 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AG076636 | Advancing MR elastography to map mechanical signatures of key AD/ADRD processes | 001 | 4 | NIH | 2/23/2026 | $44,196 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | F31CA301512 | Exploring LMTK2: A novel mediator of endocrine sensitivity in ER+ breast cancer | 000 | 1 | NIH | 4/9/2026 | $50,114 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | U01CA308978 | The Lymphoma Epidemiology of Outcomes (LEO) Cohort Study | 000 | 1 | NIH | 3/9/2026 | $1,264,356 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01CA313650 | Accelerated Biological Aging and Immunosenescence as Drivers for Racial Disparities in Monoclonal Gammopathy of Undetermined Significance (MGUS) | 000 | 1 | NIH | 5/8/2026 | $558,016 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AA031965 | Neurosteroids and Alcohol Use Disorder | 000 | 2 | NIH | 6/30/2026 | $700,490 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01CA305931 | Radiomic phenotypes for invasive and advanced breast cancer | 000 | 1 | NIH | 5/7/2026 | $722,914 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK142296 | Autophagic Processes and Hepatocellular Steatosis | 000 | 1 | NIH | 2/18/2026 | $495,130 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | UH3NS132128 | Hybrid approach for comprehensive mutation detection in a cell | 000 | 4 | NIH | 4/2/2026 | $562,212 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | F31DK146505 | Metabolism-mediated epigenetic regulation of hepatic stellate cell activation during liver fibrosis | 001 | 1 | NIH | 3/31/2026 | $0 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | F31DK146505 | Metabolism-mediated epigenetic regulation of hepatic stellate cell activation during liver fibrosis | 000 | 1 | NIH | 3/31/2026 | $49,538 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | F31AI197938 | Designing Engineered Stem Cell Therapies for Immune-Mediated Demyelinating Diseases | 000 | 1 | NIH | 6/23/2026 | $50,114 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | RF1AG037491 | Understanding the role of TDP-43 in Alzheimer’s disease, FTLD and Related Disorders | 000 | 16 | NIH | 5/7/2026 | $3,391,515 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01EB039412 | Charge-sharing-correction for clinical multi-energy CT: Practical implementation on a whole-body photon-counting-detector CT scanner | 000 | 1 | NIH | 6/30/2026 | $620,179 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R03EB039127 | Image-Based Analysis of Dose-Dependent Radiation Effects on the Myocardium following Cardiac Radioablation Therapy | 000 | 1 | NIH | 6/23/2026 | $80,200 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01CA300454 | Blood-based tumor and immune markers for risk stratification and monitoring treatment response in oligometastatic prostate cancer | 000 | 1 | NIH | 3/24/2026 | $667,710 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01MH143024 | SCH: Real-Time Engagement of Children for Individualizing Behavior Management with Wearables | 000 | 1 | NIH | 5/18/2026 | $301,092 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AI195606 | Establishing the etiology of chronic placental villitis of unknown etiology | 000 | 1 | NIH | 3/30/2026 | $689,081 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AI195565 | Regulation of target cell survival by TBK1 and IKKe | 000 | 1 | NIH | 2/23/2026 | $624,521 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R21CA302685 | Improving Treatment Sensitivity through Syk using Novel Translational Models of Uveal Melanoma | 000 | 1 | NIH | 5/14/2026 | $415,000 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | U01CA299909 | Prospective Detection and Monitoring of NF1 peripheral nerve sheath tumors using cell-free DNA | 000 | 1 | NIH | 6/11/2026 | $688,661 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R21AG097887 | Real world impact of glucagon-like peptide receptor agonist (GLP-1 RA) use on older adults | 000 | 1 | NIH | 3/13/2026 | $443,850 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL176479 | Quantitative and longitudinal assessment of diffuse pulmonary parenchymal disease using lung ultrasound surface wave elastography | 001 | 1 | NIH | 7/2/2026 | -$661,884 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL176479 | Quantitative and longitudinal assessment of diffuse pulmonary parenchymal disease using lung ultrasound surface wave elastography | 001 | 1 | NIH | 7/2/2026 | $661,884 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL176479 | Quantitative and longitudinal assessment of diffuse pulmonary parenchymal disease using lung ultrasound surface wave elastography | 000 | 1 | NIH | 6/25/2026 | $661,884 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK145433 | Acute Kidney Injury in Care Transitions: The ACT Pragmatic Trial | 000 | 1 | NIH | 3/3/2026 | $796,370 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R21AG101515 | Time-Efficient Inspiratory Muscle Strength Training for Reducing Sympathetic Activity and Improving Sleep in Midlife Women | 000 | 1 | NIH | 6/16/2026 | $439,258 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01CA307402 | Addressing Thyroid Cancer Overdiagnosis: AI-Driven Identification, Characterization, and Outcomes of Incidental Thyroid Nodules | 000 | 1 | NIH | 3/13/2026 | $676,067 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R37NS089757 | Longitudinal multi-modal imaging in progressive supranuclear palsy syndromes | 000 | 11 | NIH | 2/16/2026 | $3,746,535 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AG097480 | Role of Brd4 in enhancing old donor heart preservation quality via 3D chromosomal restructuring | 000 | 1 | NIH | 1/28/2026 | $660,157 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01EB038746 | Overcoming Challenging Clinical Scenarios in Non-invasive Coronary Artery Imaging using Next Generation Photon Counting Detector CT and Artificial Intelligence | 001 | 1 | NIH | 4/6/2026 | $0 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01EB038746 | Overcoming Challenging Clinical Scenarios in Non-invasive Coronary Artery Imaging using Next Generation Photon Counting Detector CT and Artificial Intelligence | 000 | 1 | NIH | 3/26/2026 | $625,527 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R21AI190265 | C. albicans Induced Immune Skewing in Early Life | 000 | 1 | NIH | 2/3/2026 | $443,850 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AI196126 | Transforming ANA Testing: Leveraging Epidemiology and AI to Detect Autoimmune Disease | 000 | 1 | NIH | 3/27/2026 | $800,097 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | K08CA299698 | Exploiting SPOP for novel synthetic lethality mechanisms in prostate cancer | 000 | 1 | NIH | 5/14/2026 | $307,381 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK145578 | Reversing abnormal metabolism in mild autonomous cortisol secretion (MACS) | 000 | 1 | NIH | 2/17/2026 | $741,387 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AI170535 | Characterizing the role of CSDE1 as a critical co-factor for VSV replication. | 000 | 4 | NIH | 2/18/2026 | $403,500 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK122948 | Lipotoxicity and Liver Inflammation | 000 | 7 | NIH | 2/12/2026 | $583,961 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | U2CDK143937 | Next Generation KUH Researchers (GENERATOR) | 001 | 2 | NIH | 6/11/2026 | $368,742 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AR083873 | Local Delivery of AdipoRon to Treat Arthrofibrosis | 000 | 2 | NIH | 6/11/2026 | $325,826 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01CA298083 | Using germline and somatic genetics to elucidate glioma risk and improve patient outcomes | 000 | 2 | NIH | 7/1/2026 | $469,453 |
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