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 | Issue Date FY: 2026 ( Subtotal = $274,695,803 ) (Continued on the next page) |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | RF1AG037491 | Understanding the role of TDP-43 in Alzheimer’s disease, FTLD and Related Disorders | 001 | 16 | NIH | 9/2/2026 | $0 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | RF1AG037491 | Understanding the role of TDP-43 in Alzheimer’s disease, FTLD and Related Disorders | 000 | 16 | NIH | 5/7/2026 | $3,391,515 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01CA300454 | Blood-based tumor and immune markers for risk stratification and monitoring treatment response in oligometastatic prostate cancer | 000 | 1 | NIH | 3/24/2026 | $667,710 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01MH143024 | SCH: Real-Time Engagement of Children for Individualizing Behavior Management with Wearables | 000 | 1 | NIH | 5/18/2026 | $301,092 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | K08CA308863 | Unraveling the Mechanisms of Cyclin D1-Induced Replication Stress and DNA Damage Repair Dependencies in Mantle Cell Lymphoma: A Path to Novel Therapeutic Strategies for High-Risk Disease | 000 | 1 | NIH | 8/6/2026 | $324,272 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL184127 | Thrombolysis Resistance in Acute Ischemic Stroke | 000 | 1 | NIH | 8/6/2026 | $593,663 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL183399 | Propofol-associated Hypertriglyceridemia: a mechanistic and causal inference analysis | 001 | 1 | NIH | 8/24/2026 | $0 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL183399 | Propofol-associated Hypertriglyceridemia: a mechanistic and causal inference analysis | 000 | 1 | NIH | 8/7/2026 | $781,013 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK148528 | Islet Function in Gestational Diabetes | 000 | 1 | NIH | 8/18/2026 | $569,882 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01CA305931 | Radiomic phenotypes for invasive and advanced breast cancer | 000 | 1 | NIH | 5/7/2026 | $722,914 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AA031965 | Neurosteroids and Alcohol Use Disorder | 000 | 2 | NIH | 6/30/2026 | $700,490 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK142296 | Autophagic Processes and Hepatocellular Steatosis | 000 | 1 | NIH | 2/18/2026 | $495,130 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R21HL181601 | Hypnotic Resistance: Definitions, Prevalence, and Risk Factors | 000 | 1 | NIH | 8/10/2026 | $242,100 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | K08AA033404 | Digital Twins for Accelerating Clinical Trial Innovation in Alcohol-Associated Hepatitis | 000 | 1 | NIH | 8/21/2026 | $202,176 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | F31AI197938 | Designing Engineered Stem Cell Therapies for Immune-Mediated Demyelinating Diseases | 000 | 1 | NIH | 6/23/2026 | $50,114 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | RF1AG044615 | Respiratory Control in Old Age | 000 | 14 | NIH | 8/11/2026 | $1,230,527 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R21AI203622 | A Translational Precision-Cut Lung Slice Model for Host-Response and Therapeutic Testing in Pneumocystis Pneumonia | 000 | 1 | NIH | 8/25/2026 | $242,100 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R03EB039127 | Image-Based Analysis of Dose-Dependent Radiation Effects on the Myocardium following Cardiac Radioablation Therapy | 000 | 1 | NIH | 6/23/2026 | $80,200 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL188641 | CD40: a gatekeeper of natural antibody production in atherosclerosis | 000 | 1 | NIH | 8/11/2026 | $820,111 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL171508 | Addressing differential performance by socioeconomic status in Artificial Intelligence (AI) models for childhood asthma | 000 | 2 | NIH | 8/24/2026 | $475,228 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R35GM161172 | Post-Transcriptional Regulations in Stem Cell Fate Decisions | 000 | 1 | NIH | 8/14/2026 | $443,850 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | UG3DE035059 | Comprehensive Periodontal Therapy to Improve Oral and Cardiometabolic Health in Prediabetes | 000 | 1 | NIH | 8/14/2026 | $575,803 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL185686 | HOPE: Advancing HFpEF Management Through Evidence-based Treatment Optimization and Outcome Prediction | 000 | 1 | NIH | 7/30/2026 | $801,170 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | U01CA299909 | Prospective Detection and Monitoring of NF1 peripheral nerve sheath tumors using cell-free DNA | 000 | 1 | NIH | 6/11/2026 | $688,661 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AG094714 | Impact of menopause on blood pressure regulation during exercise | 000 | 1 | NIH | 8/4/2026 | $678,987 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R21CA302685 | Improving Treatment Sensitivity through Syk using Novel Translational Models of Uveal Melanoma | 000 | 1 | NIH | 5/14/2026 | $415,000 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | F30HL188450 | Unraveling the role of V-domain immunoglobulin suppressor of T cell activation (VISTA) in atherosclerosis. | 000 | 1 | NIH | 8/28/2026 | $50,314 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK143945 | Cholangiocyte Pathobiology in Cholestatic Liver Disease | 000 | 1 | NIH | 7/22/2026 | $671,966 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01NS142427 | Acute and Chronic Repercussions of Spinal Cord Stimulation following Spinal Cord Injury | 000 | 1 | NIH | 7/20/2026 | $622,784 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R21AG101515 | Time-Efficient Inspiratory Muscle Strength Training for Reducing Sympathetic Activity and Improving Sleep in Midlife Women | 001 | 1 | NIH | 8/28/2026 | $0 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R21AG101515 | Time-Efficient Inspiratory Muscle Strength Training for Reducing Sympathetic Activity and Improving Sleep in Midlife Women | 000 | 1 | NIH | 6/16/2026 | $439,258 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01CA307402 | Addressing Thyroid Cancer Overdiagnosis: AI-Driven Identification, Characterization, and Outcomes of Incidental Thyroid Nodules | 000 | 1 | NIH | 3/13/2026 | $676,067 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R21AI200456 | “Targeting Phosphoglucomutase in Pneumocystis Pneumonia” | 000 | 1 | NIH | 7/13/2026 | $441,100 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AI195557 | Understanding iPSC reprogramming using single cycle Measles vector | 000 | 1 | NIH | 7/14/2026 | $795,316 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R21AG097887 | Real world impact of glucagon-like peptide receptor agonist (GLP-1 RA) use on older adults | 000 | 1 | NIH | 3/13/2026 | $443,850 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK145458 | Ultrasound Imaging Biomarkers of Crohn's Disease | 000 | 1 | NIH | 7/28/2026 | $694,443 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01DK144208 | Discovering ADPKD Modifier Genes and Mechanisms via Zebrafish Genetics | 000 | 1 | NIH | 7/28/2026 | $748,694 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | U19AG102336 | Mayo Clinic Study of Aging U19 | 000 | 1 | NIH | 8/18/2026 | $4,496,369 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R03HL187208 | Evaluating the Combined Immunomodulatory Effect of Macrolides and Corticosteroids in Hospitalized Patients with Community Acquired Pneumonia (CAP) | 000 | 1 | NIH | 8/25/2026 | $240,600 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AA033316 | Mechanistic Insights into Topiramate Response in Comorbid AUD and PTSD: From patients to cells | 000 | 1 | NIH | 8/27/2026 | $433,056 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | F31CA310302 | Improving Efficacy of TSHR-CART by Targeting Suppressive Myeloid Cells | 000 | 1 | NIH | 8/28/2026 | $50,114 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01CA315861 | Individualized DNA junctions for glioma response assessment via longitudinal liquid biopsies | 000 | 1 | NIH | 7/24/2026 | $565,423 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL176479 | Quantitative and longitudinal assessment of diffuse pulmonary parenchymal disease using lung ultrasound surface wave elastography | 001 | 1 | NIH | 7/2/2026 | -$661,884 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01HL176479 | Quantitative and longitudinal assessment of diffuse pulmonary parenchymal disease using lung ultrasound surface wave elastography | 001 | 1 | NIH | 7/2/2026 | $661,884 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | UH3NS132128 | Hybrid approach for comprehensive mutation detection in a cell | 000 | 4 | NIH | 4/2/2026 | $562,212 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01AA031167 | Multi-site DBS with precise timing control focusing on synaptic plasticity | 000 | 2 | NIH | 6/30/2026 | $543,111 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | F31CA301512 | Exploring LMTK2: A novel mediator of endocrine sensitivity in ER+ breast cancer | 000 | 1 | NIH | 4/9/2026 | $50,114 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | R01LM014760 | Virtual World-based Cardiac Rehabilitation to Promote Data-Powered Cardiovascular Health Among Cardiac Patients: A Multicenter Randomized Clinical Trial | 000 | 2 | NIH | 7/21/2026 | $373,996 |
| | 2026 | 2026 | MAYO CLINIC | 200 1ST ST SW | ROCHESTER | MN | 55905-0001 | OLMSTED | USA | UH3NS123066 | Optimizing Pharmacotherapy with Noninvasive Wearable Sensors and Subscalp EEG | 000 | 4 | NIH | 8/4/2026 | $699,582 |
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