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Design and directed evolution of an 'Edmanase' enzyme for high-throughput peptide sequencing.

Award Number: R44GM130185
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/13/2018
PERIOD OF PERFORMANCE END DATE: 08/31/2022

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Design and directed evolution of an 'Edmanase' enzyme for high-throughput peptide sequencing. - ABSTRACT More accessible and cost-effective technologies for analysis of the proteome would accelerate biological and medical research. The goal of this proposal is to develop enzymatic reagents to enable creation of a highly-scalable digital protein analysis technology. The approach is broadly applicable and greatly improves upon cost, sensitivity, usability, and throughput of current approaches.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = $0 )
2023	2021	ENCODIA INC	5785 OBERLIN DR	SAN DIEGO	CA	92121	SAN DIEGO	USA	Biomedical Research and Research Training	000	3	7/20/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $0 )
2022	2021	ENCODIA, INC.	11045 ROSELLE ST STE 120	SAN DIEGO	CA	92121	SAN DIEGO	USA	Biomedical Research and Research Training	000	3	3/7/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2021 ( Subtotal = $714,694 )
2021	2021	ENCODIA, INC.	11045 ROSELLE ST STE 120	SAN DIEGO	CA	92121	SAN DIEGO	USA	Biomedical Research and Research Training	000	3	8/31/2021	NON-COMPETING CONTINUATION	$714,694
														Subtotal = $714,694

Issue Date FY: 2020 ( Subtotal = $749,718 )
2020	2020	ENCODIA, INC.	11045 ROSELLE ST STE 120	SAN DIEGO	CA	92121	SAN DIEGO	USA	Biomedical Research and Research Training	000	2	9/9/2020	COMPETING CONTINUATION	$749,718
														Subtotal = $749,718

Grand Total All Awards = $1,464,412

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Design and directed evolution of an 'Edmanase' enzyme for high-throughput peptide sequencing.

Award Number: R44GM130185

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/13/2018

PERIOD OF PERFORMANCE END DATE: 08/31/2022

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