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A Direct-Reading Liquid Crystal Based Formaldehyde Dosimeter for Personal Exposure Monitoring

Award Number: R44ES026474
ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 02/01/2016
PERIOD OF PERFORMANCE END DATE: 05/31/2021

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A Direct-Reading Liquid Crystal Based Formaldehyde Dosimeter for Personal Exposure Monitoring - Platypus Technologies aims to advance the liquid crystal (LC) based molecular analytic detection of formaldehyde that it established with SBIR Phase I support to complete the development and integrate its innovative LC-based technology into product forms for rapid identification of formaldehyde emissions for short term and time-weighted exposure (TWA). Formaldehyde is a known carcinogen, and workplace exposure limits to this compound are enforced by the US Occupational Safety and Health Administration (OSHA) and Environmental Protection Agency (EPA). Despite its toxicity upon both short-term and long-term exposure, formaldehyde is widely used for manufacturing materials used in residential construction, vehicles, and medical laboratories [7]. Just recently in 2016, the EPA published new rules to further limit formaldehyde from wood products [21]. Industries affected by the OSHA and EPA limits (new construction buildings, automotive, aerospace, medical laboratories and wood products manufacturing) total to a $212M market opportunity for formaldehyde detection. Current devices for detection and monitoring of formaldehyde, which include electrochemical devices, colorimetric detectors, diffusion badges and sorbent tubes have significant disadvantages. Electrochemical devices are expensive and require calibration. Colorimetric detectors produce difficult-to-interpret results. While diffusion badges do not require a pump like sorbent tubes, both depend on laboratory analysis that can take 7-14 days. The LC-based sensors that Platypus technologies invented in Phase I exhibit a striking and readily quantified optical transition (from dark to bright) when exposed to formaldehyde. In Phase II, we will complete the development of this innovative technology and integrate these new LC materials into two devices that provide unique advantages for formaldehyde detection, which include direct and easy-to-read, real-time exposure results with high accuracy at a low cost. The first device to be developed in Phase II is a sensor for rapid identification of formaldehyde emission at OSHA’s short-term exposure limit: 2 ppm in less than 15 minutes. The second device to be fabricated is a wearable dosimeter badge to monitor TWA exposure up to 750 ppb formaldehyde for 8 hrs. Additionally, we will fabricate an electronic reader with wireless connectivity to read the LC-based devices and generate exposure assessment reports that facilitate OSHA’s recordkeeping requirements. Following completion of Phase II efforts, Platypus Technologies will seek to integrate these devices into a multiplex platform that leverages other LC-based chemistries for identification of multiple toxic gases and position the devices for commercialization.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2022 ( Subtotal = $0 )
2022	2019	PLATYPUS TECHNOLOGIES, LLC	5520 NOBEL D STE 100	MADISON	WI	53711	DANE	USA	Environmental Health	000	3	11/4/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2019 ( Subtotal = $495,033 )
2019	2019	PLATYPUS TECHNOLOGIES, LLC	5520 NOBEL D STE 100	MADISON	WI	53711	DANE	USA	Environmental Health	000	3	6/13/2019	NON-COMPETING CONTINUATION	$495,033
														Subtotal = $495,033

Issue Date FY: 2018 ( Subtotal = $487,008 )
2018	2018	PLATYPUS TECHNOLOGIES, LLC	5520 NOBEL D STE 100	MADISON	WI	53711	DANE	USA	Environmental Health	000	2	5/9/2018	COMPETING CONTINUATION	$487,008
														Subtotal = $487,008

Grand Total All Awards = $982,041

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A Direct-Reading Liquid Crystal Based Formaldehyde Dosimeter for Personal Exposure Monitoring

Award Number: R44ES026474

ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 02/01/2016

PERIOD OF PERFORMANCE END DATE: 05/31/2021

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