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An implantable chronic 128 channel macro and micro ECoG system with integrated recording, stimulation, and impedance measuring capabilities

Award Number: R43NS093729
ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 06/15/2015
PERIOD OF PERFORMANCE END DATE: 08/31/2017

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An implantable chronic 128 channel macro and micro ECoG system with integrated recording, stimulation, and impedance measuring capabilities - ¿ DESCRIPTION (provided by applicant): The objective of this proposal is to design, develop, and validate a commercially viable "human-use" smart 128-channel macro & micro ECoG microsystem with integrated recording, stimulation, and impedance measuring capabilities for epilepsy monitoring. The microsystem comprises of a state-of-art microelectronic signal processing component linked to a macro & micro integrated ECoG grid via a thin, highly flexible, bio- compatible micro-ribbon cable on one end and a single percutaneous flexible-cable ("pigtail") on the other end. The custom multiplexing ASIC electronics is capable of 128-channel recordings at 16-bit resolution and has fast settle capability (for stimulation option) and patient safety circuitry. The component is contained on a printed circuit board and is encapsulated with Parylene-C and Silicone. The encapsulated microelectronic component unit is encased in a titanium case and resides subcutaneously between the skin and the skull. The integrated microsystem would have unique "snow-flake" shape grid design containing alternate rows of macro and micro channels. The phase-I would target a short-term goal of developing, bench testing and validating in adult sheep model the complete implantable ECoG microsystem that can be translated to research and clinical lab in the shortest time frame.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2018 ( Subtotal = -$3 )
2018	2016	BLACKROCK MICROSYSTEMS, LLC	630 S KOMAS DR STE 200	SALT LAKE CITY	UT	84108	SALT LAKE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	2	1/24/2018	NON-COMPETING CONTINUATION	-$3
														Subtotal = -$3

Issue Date FY: 2016 ( Subtotal = $349,542 )
2016	2016	BLACKROCK MICROSYSTEMS LLC	630 KOMAS DRIVE	SALT LAKE CITY	UT	84108	SALT LAKE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	2	6/15/2016	NON-COMPETING CONTINUATION	$349,542
														Subtotal = $349,542

Issue Date FY: 2015 ( Subtotal = $359,615 )
2015	2015	BLACKROCK MICROSYSTEMS LLC	630 KOMAS DRIVE	SALT LAKE CITY	UT	84108	SALT LAKE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	1	6/9/2015	NEW	$359,615
														Subtotal = $359,615

Grand Total All Awards = $709,154

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An implantable chronic 128 channel macro and micro ECoG system with integrated recording, stimulation, and impedance measuring capabilities

Award Number: R43NS093729

ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 06/15/2015

PERIOD OF PERFORMANCE END DATE: 08/31/2017

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