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Development of a rapid screening test for the detection of dihydroanatoxin-a

Award Number: R43ES034301
ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/07/2023
PERIOD OF PERFORMANCE END DATE: 06/30/2025

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Development of a rapid screening test for the detection of dihydroanatoxin-a - Project Summary Dihydroanatoxin (dhATX) derived from cyanobacteria is a rapidly emerging global problem that negatively impacts human and animal health. Poisoning induced by dhATX is characterized by a broad array of neurological and cardiovascular symptoms with extremes of severity which can lead to fatality. Therefore, efficient, and effective detection, prevention, control, and mitigation technologies are critically needed to prevent exposures. The only available technology to detect the presence of dhATX is expensive, time consuming, and labor intensive, allowing only sporadic testing to be performed. This lack of rapid, simple, inexpensive testing capability increases the chances of human and animal exposures and associated health problems. Based on our current progress in developing rapid assays for environmental toxins, we will develop a rapid, quantitative, and cost- effective receptor binding assay for detecting dhATX in the field setting. Our test platform will likely emerge as an integral component of monitoring programs domestically and internationally to improve dhATX detection, and will provide an effective tool for public health officials to act quickly to reduce dhATX exposures.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2023	ATTOGENE CORPORATION	3913 TODD LN	AUSTIN	TX	78744	TRAVIS	USA	Environmental Health	000	1	8/6/2025	NEW	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $259,002 )
2023	2023	ATTOGENE CORP	3913 TODD LN	AUSTIN	TX	78744	TRAVIS	USA	Environmental Health	000	1	7/6/2023	NEW	$259,002
														Subtotal = $259,002

Grand Total All Awards = $259,002

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Development of a rapid screening test for the detection of dihydroanatoxin-a

Award Number: R43ES034301

ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/07/2023

PERIOD OF PERFORMANCE END DATE: 06/30/2025

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