Thursday, July 17, 2025 7/17/2025

Development of biopsy devices for improved preservation of multiple biopsy tissue samples

Award Number: R43ES028560
ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/15/2017
PERIOD OF PERFORMANCE END DATE: 12/31/2018

Group Awards By:

View Award Description

Development of biopsy devices for improved preservation of multiple biopsy tissue samples - Project Summary Molecular medicine holds promise for advancing medical diagnosis and treatment if biomarkers can be accurately assessed in tissues, for example in tumors. The long-term objective of the project is to bring to market new tools for better biopsy tissue acquisition, processing and storing. A first new biopsy device aims to acquire multiple samples into a cartridge and to stabilize the biopsy tissue samples shortly after they are cut, for example by freezing, and thus prevent changes in biomarker levels due to ischemia in the excised tissue samples. A second new biopsy device aims to split the tissue samples into two parts, to store one part in a way that will optimally maintain the histology of the tissue (e.g. formalin fixation) and the second part in a way that will optimally maintain the biomarker levels in the tissue (e.g. freezing). The specific aims of this Phase I project are to develop a prototype core biopsy device for sequential, multiple samples acquisition through a single needle insertion; to develop vacuum-assisted biopsy device with dual- mode preservation for short term storage of the tissue samples; and to compare histology sections and biomarkers qualities as achieved by the prototype biopsy devices versus clinical-grade biopsy device A biopsy methodology that preserves the tissue morphology and stabilizes the biomolecular profile of the cells in the biopsy samples is expected to be used for many clinical and research applications and to achieve wide commercial market. In particular, such a device can be used to monitor the effect of targeted treatment and to improve the management of patients by the use of individualized therapy that targets the specific characteristics of the diseased tissue in each patient.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2019 ( Subtotal = $0 )
2019	2017	ROBIN MEDICAL, INC.	6607 BONNIE RIDGE DR APT 101	BALTIMORE	MD	21209	BALTIMORE CITY	USA	Environmental Health	000	1	6/28/2019	NEW	$0
														Subtotal = $0

Issue Date FY: 2017 ( Subtotal = $225,000 )
2017	2017	ROBIN MEDICAL, INC.	3502 GARDENVIEW RD	PIKESVILLE	MD	21208	BALTIMORE	USA	Environmental Health	000	1	9/12/2017	NEW	$225,000
														Subtotal = $225,000

Grand Total All Awards = $225,000

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Development of biopsy devices for improved preservation of multiple biopsy tissue samples

Award Number: R43ES028560

ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/15/2017

PERIOD OF PERFORMANCE END DATE: 12/31/2018

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer