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AFM based nanoscale IR Spectroscopy (AFM-IR) as a characterization platform for P

Award Number: R42GM100657
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 05/01/2012
PERIOD OF PERFORMANCE END DATE: 11/30/2017

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AFM based nanoscale IR Spectroscopy (AFM-IR) as a characterization platform for P - DESCRIPTION (provided by applicant): Anasys Instruments and Prof. Lynne Taylor of Purdue propose to develop nanoscale chemical characterization capabilities for drug formulation research. This project will build on successful Phase I research demonstrating feasibility of atomic force microscope-based infrared spectroscopy (AFM-IR) in pharmaceutical applications. This Phase II research will advance techniques for efficiently determining morphological and chemical properties of nanostructured drug formulations, leading to improvements in drug solubility. This project will overcome key limitations of existing characterization tools, includin the limitations of current AFM-IR technology. The proposed research will provide a critical new characterization tool for pharmaceutical research, will enable a large commercial and research market, and is expected to have significant downstream impacts on improving drug solubility and efficacy.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2018 ( Subtotal = $0 )
2018	2016	ANASYS INSTRUMENTS CORP.	325 CHAPALA ST.	SANTA BARBARA	CA	93101	SANTA BARBARA	USA	Biomedical Research and Research Training	000	3	5/10/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2016 ( Subtotal = $481,535 )
2016	2016	ANASYS INSTRUMENTS CORPORATION	121 GRAY AVENUE	SANTA BARBARA	CA	93101	SANTA BARBARA	USA	Biomedical Research and Research Training	000	3	11/18/2015	NON-COMPETING CONTINUATION	$481,535
														Subtotal = $481,535

Issue Date FY: 2015 ( Subtotal = $495,193 )
2015	2015	ANASYS INSTRUMENTS CORPORATION	121 GRAY AVENUE	SANTA BARBARA	CA	93101	SANTA BARBARA	USA	Biomedical Research and Research Training	000	2	11/28/2014	COMPETING CONTINUATION	$495,193
														Subtotal = $495,193

Grand Total All Awards = $976,728

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AFM based nanoscale IR Spectroscopy (AFM-IR) as a characterization platform for P

Award Number: R42GM100657

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 05/01/2012

PERIOD OF PERFORMANCE END DATE: 11/30/2017

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