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NEURO-MICRO-TRANSPONDERS FOR A MINIMALLY-INVASIVE PERIPHERAL NERVE INTERFACE

Award Number: R41NS061603
ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/15/2008
PERIOD OF PERFORMANCE END DATE: 06/30/2009

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NEURO-MICRO-TRANSPONDERS FOR A MINIMALLY-INVASIVE PERIPHERAL NERVE INTERFACE - DESCRIPTION (provided by applicant): The MicroTransponder, Inc. technology portfolio consists of novel wireless micro- systems that are being developed as platforms for minimally invasive micro-implants for a host of biomedical applications. This plan will establish the feasibility of our micro- transponder technology for peripheral nerve interface applications in general and as an intra-neural interface with sensory/motor fibers in general. Our core invention is based on the proven wireless technology widely employed in commercial "Radio Frequency Identification Devices" (RFIDs) whose elegant simplicity is ideal for extreme miniaturization. Our "Neuro-Micro-Transponders" (NeuTs) simply combine neural interface micro-electronics with the basic RFID identification code every time a neural spike is detected. This plan is designed to test the wireless performance of a variety of micro-transponder sizes over the course of long-term implantation within the hind limb of rats. These methods will be employed to test an innovative system designed to enable effective operation of micro-transponders implanted into deep body tissues, far beyond the limits of this wireless technology. PUBLIC HEALTH RELEVANCE: This project will develop minimally invasive implants to interface with peripheral nerves for a variety of biomedical applications. In particular, intra-neural implants with specialized electrodes to interface with the sensory and motor fibers remaining in amputated peripheral nerves will be employed for neuroprosthesis with artificial limbs capable of natural sensation and movement. In addition, larger implants will be developed for extra-neural applications, especially for the treatment of painful neuropathy by stimulation with a multitude of micro-transponder implants injected throughout the subcutaneous terminal fields of diseased sensory nerves. Public Health Relevance: This Public Health Relevance is not available.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2008 ( Subtotal = $113,354 )
2008	2008	MICRO TRANSPONDER INC	12147 LUEDERS STREET	DALLAS	TX	75230	DALLAS	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	1	7/7/2008	NEW	$113,354
														Subtotal = $113,354

Grand Total All Awards = $113,354

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NEURO-MICRO-TRANSPONDERS FOR A MINIMALLY-INVASIVE PERIPHERAL NERVE INTERFACE

Award Number: R41NS061603

ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/15/2008

PERIOD OF PERFORMANCE END DATE: 06/30/2009

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