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Development of Mechanisms Underlying Human Motor Learning

Award Number: R35NS122266
ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 05/01/2021
PERIOD OF PERFORMANCE END DATE: 04/30/2029

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Development of Mechanisms Underlying Human Motor Learning - Movement abilities affect a child’s physical, social and emotional well-being, as well as their educational success—all of which can last a lifetime. Movement is fundamental to the development of abilities across domains (motor, cognitive), because it underlies a child’s ability to explore and interact with the environment and other people. How children learn movement is a complex process that changes with development, experience and injury. It depends on a suite of interacting brain mechanisms that are driven by different signals (e.g. reward, error), have different learning rates, retention capacities, contextual dependencies and vulnerabilities to neurological damage. A key gap in human neuroscience is our limited understanding of this complex interplay. We propose to leverage recently developed home-based experimental tasks and new laboratory methods to generate high resolution time courses for different components of childhood motor learning, and then determine how they are affected by neurological lesions. With these data we can create a detailed flowchart of movement learning capacity and the effects of disease, as a function of age and developmental markers. This would provide the comprehensive understanding required to generate tailored therapeutic training strategies targeted to age, developmental maturity, gender, and disease state.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $686,748 )
2025	2025	HUGO W. MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER, INC.	707 N BROADWAY	BALTIMORE	MD	21205	BALTIMORE CITY	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	5	7/24/2025	NON-COMPETING CONTINUATION	$686,748
2025	2023	HUGO W. MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER, INC.	707 N BROADWAY	BALTIMORE	MD	21205	BALTIMORE CITY	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	3	6/16/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $686,748

Issue Date FY: 2024 ( Subtotal = $666,145 )
2024	2024	HUGO W. MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER, INC.	707 N BROADWAY	BALTIMORE	MD	21205	BALTIMORE CITY	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	4	5/15/2024	NON-COMPETING CONTINUATION	$666,145
														Subtotal = $666,145

Issue Date FY: 2023 ( Subtotal = $686,748 )
2023	2023	HUGO W. MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER, INC.	707 N BROADWAY	BALTIMORE	MD	21205	BALTIMORE CITY	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	3	5/2/2023	NON-COMPETING CONTINUATION	$686,748
														Subtotal = $686,748

Issue Date FY: 2022 ( Subtotal = $686,748 )
2022	2022	HUGO W. MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER, INC.	707 N BROADWAY	BALTIMORE	MD	21205	BALTIMORE CITY	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	2	5/6/2022	NON-COMPETING CONTINUATION	$686,748
														Subtotal = $686,748

Issue Date FY: 2021 ( Subtotal = $642,249 )
2021	2021	HUGO W. MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER, INC.	707 N BROADWAY	BALTIMORE	MD	21205	BALTIMORE CITY	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	1	4/26/2021	NEW	$688,749
2021	2021	HUGO W. MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER, INC.	707 N BROADWAY	BALTIMORE	MD	21205	BALTIMORE CITY	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	1	6/4/2021	NEW	-$46,500
														Subtotal = $642,249

Grand Total All Awards = $3,368,638

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Development of Mechanisms Underlying Human Motor Learning

Award Number: R35NS122266

ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 05/01/2021

PERIOD OF PERFORMANCE END DATE: 04/30/2029

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