Wednesday, December 31, 2025 12/31/2025

Advancement of an Impending Hospitalization Detection Platform

Award Number: R33HL168785
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 01/01/2024
PERIOD OF PERFORMANCE END DATE: 12/31/2026

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Advancement of an Impending Hospitalization Detection Platform - Abstract Heart, Lung, Blood, and Sleep (HLBS) conditions such as heart failure, COPD, and pneumonia are among the most common causes of hospitalizations. Many of such hospitalizations are thought to be avoidable with early recognition and intervention. Today, patient-reported symptoms represent the primary means of detecting impending hospitalizations, but because symptoms are late indicators of disease, this results in days to weeks of delay in receiving care. We developed a non-contact adherence-independent longitudinal bed-sensing platform to detect early physiologic signs of impending hospitalizations before patients recognize or self-report symptoms. Preliminary results from our bed-based mechanical sensors suggest that the technology can learn patient-specific baselines during clinical stability and can recognize excursions from baseline in the early stages of developing illness. Here, we propose a milestone-based project aimed at collecting human training datasets and developing generalizable models that can recognize impending hospitalizations in the home with a focus on the underrepresented populations of San Diego and Imperial Valley counties. Doing so will encourage utilization and adoption across HLBS disease verticals and patient subpopulations.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2025	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Cardiovascular Diseases Research	000	2	11/4/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2025 ( Subtotal = $469,660 )
2025	2025	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Cardiovascular Diseases Research	000	2	4/15/2025	NON-COMPETING CONTINUATION	$422,694
2025	2025	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Cardiovascular Diseases Research	001	2	6/26/2025	NON-COMPETING CONTINUATION	$46,966
														Subtotal = $469,660

Issue Date FY: 2024 ( Subtotal = $871,500 )
2024	2024	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Cardiovascular Diseases Research	000	1	12/26/2023	NEW	$474,000
2024	2024	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Cardiovascular Diseases Research	001	1	7/26/2024	SUPPLEMENT FOR EXPANSION	$397,500
														Subtotal = $871,500

Grand Total All Awards = $1,341,160

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Advancement of an Impending Hospitalization Detection Platform

Award Number: R33HL168785

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 01/01/2024

PERIOD OF PERFORMANCE END DATE: 12/31/2026

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