PROJECT SUMMARY
Vaccination has had a profound impact on human health and has eradicated or almost eradicated once feared
diseases such as smallpox and polio and substantially decreased morbidity and mortality due to pneumococcus,
measles and pertussis amongst many others. The utility and cost effectiveness of vaccination has been shown
multiple times and most recently during the COVID-19 pandemic. SARS-CoV-2 has had a devastating effect on
humankind causing significant morbidity and mortality as well as major disruptions to the economy, education,
the supply chain and mental health. However, the extremely rapid development and deployment of multiple
COVID-19 vaccines has allowed society to return to a semblance of normality. These vaccines were developed
because of the large amount of money invested by governments to de-risk development and the many dedicated
vaccinologists (laboratory personnel, clinical trialists, nurses, regulatory affairs specialists, statisticians etc. in
academia, government and industry) who were committed to working on a common goal. Additionally, novel
vaccine platforms had been in development for many years so the knowledge about how these platforms could
be harnessed for COVID-19 was already present. In order to be ready for the next pandemic, we need to ensure
that there are sufficient individuals entering and staying in the field of vaccinology so that they can develop new
platforms, evaluate and dissect immune responses, perform clinical trials and have a broad understanding of the
entire vaccine development process. The overarching goal of the Integrated Training Program in Vaccinology
(ITP-Vax) is to encourage more trainees to join the field of vaccinology, particularly under-represented minorities
(URM), and to enable our existing outstanding early-career vaccinologists to excel in mentorship and to become
fully independent. To achieve this goal, we propose the following aims: Aim 1) To provide training in mentorship
to early-career investigators and assist them on their path to independence in vaccinology, and Aim 2) To provide
comprehensive training in vaccinology to post-baccalaureate or Master’s level students who are intending to
apply for a PhD or medical school in the next 1-2 years and who seek a career in vaccinology. We will also
actively engage and recruit URM’s for ITP-Vax so that we can ultimately improve diversity in vaccinology.