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SHOW-Forward: A pathway for increasing participation, enriching data, and improving access to a unique environmental epidemiology cohort

Award Number: R24ES036005
ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 04/16/2024
PERIOD OF PERFORMANCE END DATE: 03/31/2029

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SHOW-Forward: A pathway for increasing participation, enriching data, and improving access to a unique environmental epidemiology cohort - Well-characterized longitudinal epidemiological cohorts are crucial resources for identifying novel risk factors, examining exposure-outcome associations, and determining the role of biomarkers in disease development and progression. The Survey of the Health of Wisconsin (SHOW) is a unique environmental epidemiological cohort where rigorous survey methodology was used to ensure state-wide participation from Wisconsin, resulting in a representative sample. Based on our successful experience in participant recruitment, we propose to initiate SHOW-Forward to further expand the cohort, enrich already collected data and enhance its access to the research community to facilitate novel environmental epidemiology and translational research aligned with the NIEHS mission. To accomplish these goals, we propose three speciﬁc aims. First, we will expand the cohort (renamed as REACH) through continued and enhanced outreach and engagement across Wisconsin. Novel approaches for participant-centric biospecimen collection will be implemented to reduce the burden for participants from remote areas. Second, we will develop a Real-World Data Collaborative infrastructure as a foundation for secure integrative environmental health research and translation. Third, we will establish the administrative infrastructure to develop, reﬁne, and implement ethical and compliant participant recruitment, acquisition, linkage, usage, analysis and sharing of PHI- containing multi-dimensional data and annotated biospecimens in SHOW-Forward. Ultimately, this collaborative infrastructure will facilitate broad access to SHOW data and biospecimens, enable early detection and treatment of emerging health issues, improve understanding of the role of environmental and lifestyle factors, harmful chemical exposures, and genetics on human health, and unlock new pathways for evidence-based prevention of environmentally caused diseases.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $370,466 )
2026	2026	UNIVERSITY OF WISCONSIN SYSTEM	21 N PARK ST STE 6301	MADISON	WI	53715	DANE	USA	Environmental Health	000	3	3/31/2026	NON-COMPETING CONTINUATION	$370,466
														Subtotal = $370,466

Grand Total All Awards = $370,466

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SHOW-Forward: A pathway for increasing participation, enriching data, and improving access to a unique environmental epidemiology cohort

Award Number: R24ES036005

ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 04/16/2024

PERIOD OF PERFORMANCE END DATE: 03/31/2029

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