Saturday, October 16, 2021 10/16/2021

CFAR Network of Integrated Clinical Systems (CNICS)

Award Number: R24AI067039
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Group Awards By Issue Date FY or Funding FY:

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PROJECT SUMMARY / ABSTRACT Modern antiretroviral treatments alter the progression of disease, enabling the majority of HIV+ individuals to live near-normal life spans. Yet, ~ 20% of patients in the US fail to achieve long-term virologic suppression, and even for those who do, there remains the threat of multiple comorbid complications. The critical questions that arise are how will clinicians maximize treatment success, assess the sociobehavioral barriers to linkage and persistent engagement in care, understand the causes of treatment and non-treatment related complications of HIV disease, and develop interventions that maximize health and well-being of HIV infected persons over many decades of life. To address these questions, investigators need access to clinical outcomes information that is tightly linked to biologic specimens and socio-biologic and genetic data to enable translational research. The CFAR Network of Integrated Clinical Systems (CNICS) project is an established resource that has contributed substantially to the contemporary HIV research agenda. Established in 2002 and funded as an R24 research platform in 2006, CNICS is a clinic-based research network that reflects the outcomes of clinical decisions and management options used in the care of HIV infected individuals at 8 CFAR sites: UAB, U Washington, UCSF, UCSD, Case Western Reserve, Fenway Health (Brown / Harvard), U North Carolina, and Johns Hopkins. What makes CNICS unique is the way in which CNICS augments the comprehensive EHR data with a combination of other resources for research that include patient-reported and patient-centered socio-behavioral data; adjudication of key clinical events; strategic biological specimen collection; and genetic characterization of the cohort. The mission of CNICS is to provide access to the specimen and data repository to any investigator who submits an approved concept proposal. In this fashion, CNICS is a 'peer-reviewed open access' research platform available to investigators worldwide. The specific aims for this competitive renewal of CNICS leverages the robust CNICS foundation to accomplish the following: 1: Collect high quality data from a representative sample of patients; 2: Enable investigators to perform research by providing data and specimens to a diverse array of scientists worldwide; and 3: Mentor early to mid-career investigators engaged in HIV-focused research in CNICS.


Issue Date FY	Funding FY	Recipient Name	DUNS Number	City	State	CFDA Number	CFDA Program Title	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2021 ( Subtotal = $6,779,419 )
2021	2021	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	001	16	7/8/2021	COMPETING CONTINUATION	$6,592,862
2021	2021	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	000	15	1/6/2021	SUPPLEMENT FOR EXPANSION	$186,557


Issue Date FY: 2020 ( Subtotal = $4,456,708 )
2020	2020	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	000	15	7/31/2020	NON-COMPETING CONTINUATION	$4,456,708


Issue Date FY: 2019 ( Subtotal = $4,841,410 )
2019	2019	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	000	14	8/15/2019	NON-COMPETING CONTINUATION	$4,648,045
2019	2019	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	002	14	9/3/2019	SUPPLEMENT FOR EXPANSION	$0
2019	2019	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	001	14	8/30/2019	SUPPLEMENT FOR EXPANSION	$193,365
2019	2019	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	003	14	9/5/2019	NON-COMPETING CONTINUATION	$0


Issue Date FY: 2018 ( Subtotal = $4,462,005 )
2018	2018	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	000	13	8/9/2018	NON-COMPETING CONTINUATION	$4,462,005
2018	2016	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	002	11	8/20/2018	COMPETING CONTINUATION	$19,882
2018	2015	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	001	10	8/20/2018	NON-COMPETING CONTINUATION	-$19,882


Issue Date FY: 2017 ( Subtotal = $4,449,941 )
2017	2017	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	003	12	8/10/2017	NON-COMPETING CONTINUATION	$4,449,941
2017	2016	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	001	11	3/8/2017	COMPETING CONTINUATION	$359,539
2017	2016	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	002	11	3/9/2017	COMPETING CONTINUATION	$0
2017	2015	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	000	10	3/8/2017	NON-COMPETING CONTINUATION	-$359,539


Issue Date FY: 2016 ( Subtotal = $4,515,387 )
2016	2016	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	000	11	5/6/2016	COMPETING CONTINUATION	$4,515,387
2016	2016	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	001	11	6/1/2016	COMPETING CONTINUATION	$0


Issue Date FY: 2015 ( Subtotal = $3,597,088 )
2015	2015	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	000	10	8/5/2015	NON-COMPETING CONTINUATION	$3,597,088


Issue Date FY: 2014 ( Subtotal = $4,039,225 )
2014	2014	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	002	9	8/12/2014	NON-COMPETING CONTINUATION	$0
2014	2014	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	000	9	7/30/2014	NON-COMPETING CONTINUATION	$3,539,510
2014	2014	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	001	9	8/7/2014	NON-COMPETING CONTINUATION	$499,715


Issue Date FY: 2013 ( Subtotal = $3,274,075 )
2013	2013	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	000	8	8/20/2013	NON-COMPETING CONTINUATION	$3,274,075


Issue Date FY: 2012 ( Subtotal = $4,366,443 )
2012	2012	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	002	7	9/26/2012	NON-COMPETING CONTINUATION	$0
2012	2012	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	001	7	9/25/2012	NON-COMPETING CONTINUATION	$938,726
2012	2012	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	000	7	8/9/2012	NON-COMPETING CONTINUATION	$3,427,717


Issue Date FY: 2011 ( Subtotal = $3,524,697 )
2011	2011	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	001	6	8/4/2011	COMPETING CONTINUATION	$3,513,072
2011	2010	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.701	Trans-NIH Recovery Act Research Support	000	5	1/21/2011	SUPPLEMENT FOR EXPANSION	$11,625
2011	2009	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.701	Trans-NIH Recovery Act Research Support	002	4	8/29/2011	SUPPLEMENT FOR EXPANSION	$0


Issue Date FY: 2010 ( Subtotal = $3,296,487 )
2010	2010	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.701	Trans-NIH Recovery Act Research Support	005	5	9/7/2010	SUPPLEMENT FOR EXPANSION	$126,586
2010	2010	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	004	5	8/22/2010	NON-COMPETING CONTINUATION	$3,088,600
2010	2009	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	002	4	6/1/2010	NON-COMPETING CONTINUATION	$0
2010	2009	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.701	Trans-NIH Recovery Act Research Support	000	4	1/20/2010	SUPPLEMENT FOR EXPANSION	$81,301
2010	2009	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	003	4	7/27/2010	NON-COMPETING CONTINUATION	$0
2010	2009	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	001	4	3/17/2010	NON-COMPETING CONTINUATION	$0


Issue Date FY: 2009 ( Subtotal = $4,840,875 ) (Continued on the next page)
2009	2009	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.701	Trans-NIH Recovery Act Research Support	004	4	9/15/2009	SUPPLEMENT FOR EXPANSION	$1,744,488
2009	2009	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	003	4	9/4/2009	NON-COMPETING CONTINUATION	$3,096,387
2009	2008	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	002	3	6/18/2009	NON-COMPETING CONTINUATION	$0
2009	2008	UNIVERSITY OF ALABAMA AT BIRMINGHAM	063690705	BIRMINGHAM	AL	93.855	Allergy and Infectious Diseases Research	001	3	1/14/2009	NON-COMPETING CONTINUATION	$0
Grand Total All Awards = $65,368,255

Sum of Action Amount is $65,368,255;

Grand Total = $65,368,255

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CFAR Network of Integrated Clinical Systems (CNICS)

Award Number: R24AI067039

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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