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Improving momentary suicide risk identification through adaptive time sampling

Award Number: R21MH131978
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 12/16/2022
PERIOD OF PERFORMANCE END DATE: 03/31/2026

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Improving momentary suicide risk identification through adaptive time sampling - PROJECT SUMMARY/ABSTRACT Suicide rates have risen sharply over the past 20 years1. There is a need to more precisely identify proximal risk indicators for the development of near-term suicide risk in order to effectively intervene. Studies utilizing ecological momentary assessment (EMA) to collect data at several intervals per day have demonstrated that suicidal ideation (SI) and proximal risk factors change rapidly across the course of the day2. However, prior EMA studies examining SI dynamics implement stable assessments, with intervals of several hours between SI assessments across the duration of a study period3 for all participants. This one-size-fits-all approach to SI assessment fails to capture the nuanced within-person variability of the timescale of the development of acute suicide risk. In turn, we lack even a basic understanding of within-person variability in the time varying relationship between SI and its proximal risk factors. The proposed study aims to address the limitations of current assessment approaches in proximal suicide risk research through the development of a personalized, adaptive time sampling system. The specific objectives of the proposed research are to: (1) develop a novel, adaptive time assessment system that more efficiently and accurately identifies when an individual is at highest risk for SI; and (2) advance the understanding of SI and its theoretically-informed proximal risk factors at finer timescales. Data collected according to varied timing schedules in the first phase will be used to train an algorithm that generates predictions of suicide risk, predictions that will be adaptively use to determine assessment timing during the second phase of data collection. Aim 1 is to develop the adaptive time assessment system, followed by assessing the predictive accuracy of the adaptive sampling system (Aim 2) and identifying variations in person-specific effects of the relationship between SI and theoretically-informed risk factors (Aim 3). The research team (PIs: Ammerman, Jacobucci; Co-I: Cheng; Consultants: Burke) has access to world-class expertise, with extensive experience in EMA data collection in high-risk samples, machine learning for suicide prediction, longitudinal data analysis, collecting and modeling continuous data streams, and the development of adaptive assessment platforms. To meaningfully reduce suicide rates, a more nuanced understanding of suicidal thoughts and associated risk factors is required. Our adaptive assessment platform will more efficiently assess suicidal thoughts and risk factors, allowing for a closer approximation of the true associations. Indeed, there is a need to identify near-term risk factors prior to suicidal thought occurrences to successfully deliver an intervention and prevent suicidal outcomes. These findings will support the successful implementation of just-in-time adaptive interventions through increased precision of suicide risk detection and targeted intervention timing. Given the grave personal and societal cost of suicide, this work has important public health implications.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = -$12,375 )
2025	2024	UNIVERSITY OF WISCONSIN SYSTEM	21 N PARK ST STE 6301	MADISON	WI	53715	DANE	USA	Mental Health Research Grants	010	3	5/20/2025	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$45,142
2025	2024	UNIVERSITY OF NOTRE DAME DU LAC	940 GRACE HALL	NOTRE DAME	IN	46556	ST JOSEPH	USA	Mental Health Research Grants	007	2	5/17/2025	NON-COMPETING CONTINUATION	-$176,063
2025	2024	UNIVERSITY OF WISCONSIN SYSTEM	21 N PARK ST STE 6301	MADISON	WI	53715	DANE	USA	Mental Health Research Grants	002	3	4/12/2025	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$163,688
2025	2024	UNIVERSITY OF NOTRE DAME DU LAC	940 GRACE HALL	NOTRE DAME	IN	46556	ST JOSEPH	USA	Mental Health Research Grants	009	2	5/20/2025	NON-COMPETING CONTINUATION	-$19,562
2025	2024	UNIVERSITY OF WISCONSIN SYSTEM	21 N PARK ST STE 6301	MADISON	WI	53715	DANE	USA	Mental Health Research Grants	006	3	5/12/2025	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	-$221,205
2025	2024	UNIVERSITY OF NOTRE DAME DU LAC	940 GRACE HALL	NOTRE DAME	IN	46556	ST JOSEPH	USA	Mental Health Research Grants	001	2	3/31/2025	NON-COMPETING CONTINUATION	-$195,625
2025	2024	UNIVERSITY OF NOTRE DAME DU LAC	940 GRACE HALL	NOTRE DAME	IN	46556	ST JOSEPH	USA	Mental Health Research Grants	005	2	5/12/2025	NON-COMPETING CONTINUATION	$195,625
2025	2024	UNIVERSITY OF WISCONSIN SYSTEM	21 N PARK ST STE 6301	MADISON	WI	53715	DANE	USA	Mental Health Research Grants	003	3	4/15/2025	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$221,205
2025	2023	UNIVERSITY OF NOTRE DAME DU LAC	940 GRACE HALL	NOTRE DAME	IN	46556	ST JOSEPH	USA	Mental Health Research Grants	008	1	5/20/2025	NEW	-$25,580
2025	2023	UNIVERSITY OF NOTRE DAME DU LAC	940 GRACE HALL	NOTRE DAME	IN	46556	ST JOSEPH	USA	Mental Health Research Grants	004	1	5/12/2025	NEW	$25,580
2025	2023	UNIVERSITY OF NOTRE DAME DU LAC	940 GRACE HALL	NOTRE DAME	IN	46556	ST JOSEPH	USA	Mental Health Research Grants	000	1	3/31/2025	NEW	-$25,580
														Subtotal = -$12,375

Issue Date FY: 2024 ( Subtotal = $195,625 )
2024	2024	UNIVERSITY OF NOTRE DAME DU LAC	940 GRACE HALL	NOTRE DAME	IN	46556	ST JOSEPH	USA	Mental Health Research Grants	000	2	11/17/2023	NON-COMPETING CONTINUATION	$176,063
2024	2024	UNIVERSITY OF NOTRE DAME DU LAC	836 GRACE HALL	NOTRE DAME	IN	46556	ST JOSEPH	USA	Mental Health Research Grants	001	2	6/4/2024	NON-COMPETING CONTINUATION	$19,562
														Subtotal = $195,625

Issue Date FY: 2023 ( Subtotal = $234,750 )
2023	2023	UNIVERSITY OF NOTRE DAME DU LAC	940 GRACE HALL	NOTRE DAME	IN	46556	ST JOSEPH	USA	Mental Health Research Grants	000	1	12/12/2022	NEW	$234,750
2023	2023	UNIVERSITY OF NOTRE DAME DU LAC	940 GRACE HALL	NOTRE DAME	IN	46556	ST JOSEPH	USA	Mental Health Research Grants	001	1	12/19/2022	NEW	$0
														Subtotal = $234,750

Grand Total All Awards = $418,000

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Improving momentary suicide risk identification through adaptive time sampling

Award Number: R21MH131978

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 12/16/2022

PERIOD OF PERFORMANCE END DATE: 03/31/2026

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