| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2026 ( Subtotal = $31,548,501 ) (Continued on the next page) |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01AI104987 | Beta-Lactam Resistance Mechanisms of Staphylococcus aureus | 000 | 14 | NIH | 1/29/2026 | $630,355 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | F32AI191525 | Revealing the Structural Determinants of TCR Cross-Recognition via Extended Positional Scanning | 000 | 2 | NIH | 4/17/2026 | $82,048 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01AG091375 | A macrocyclic peptide platform for the discovery of functional tau epitopes | 001 | 2 | NIH | 2/27/2026 | $60,374 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01AG091375 | A macrocyclic peptide platform for the discovery of functional tau epitopes | 000 | 2 | NIH | 12/16/2025 | $543,357 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R35GM147029 | Computational Biomechanics Modeling of Inflammation | 000 | 5 | NIH | 7/17/2026 | $391,250 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | H79SM090642 | Northwest Indiana Identification and Management of Pediatric Experiences of Trauma and Underlying Stress (NWI IMPETUS) | 004 | 4 | SAMHSA | 6/30/2026 | $599,930 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01EY036107 | Selective Inhibition of GRP 94 to Treat Ocular Hypertension and Glaucoma | 000 | 3 | NIH | 7/27/2026 | $591,767 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | AY2AX000128 | TRANSFORM-L: Transforming lymphatic disease management-from filariasis to chronic conditions | 000 | 1 | NIH | 3/30/2026 | $350,000 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R21AI200304 | Tyloxapol Inhibition of Mycobacterial Type VII Secretory Activity | 000 | 1 | NIH | 6/1/2026 | $197,500 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01AI198244 | Clostridiodes difficile spore germination and therapeutic intervention | 000 | 1 | NIH | 5/26/2026 | $769,354 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01AI195933 | An Inhibitor Class That Abrogates Antibiotic Resistance in Methicillin-Resistant Staphylococcus aureus | 000 | 1 | NIH | 5/26/2026 | $748,964 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | U01CA269195 | Adapting a point of use test card, the chemoPAD, for protecting chemotherapy drug quality in sub-Saharan Africa | 000 | 5 | NIH | 7/16/2026 | $423,268 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01CA270147 | Engineering the Next Generation of Safer Hsp90 Inhibitors | 001 | 4 | NIH | 4/17/2026 | $45,381 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01CA270147 | Engineering the Next Generation of Safer Hsp90 Inhibitors | 000 | 4 | NIH | 1/12/2026 | $408,431 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01CA297220 | Developing isoform-selective Hsp90 inhibitors for monotherapy and enhanced immunotherapy against lethal prostate cancer | 000 | 2 | NIH | 6/18/2026 | $541,851 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R35GM160331 | A Molecular Recognition Guidebook for Targeting Protein Loops with Covalent Ligands | 000 | 2 | NIH | 8/20/2026 | $434,500 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R35GM158092 | Targeting Gram-Negative Bacteria for Antibacterial Strategies | 000 | 2 | NIH | 8/5/2026 | $414,725 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01NS140152 | Endothelin signaling in neural stem cell homeostasis and remyelination | 000 | 2 | NIH | 7/14/2026 | $424,106 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | P01AI127338 | Harnessing the Power of Experimental Genetic Crosses to Probe Drug Resistance in Malaria | 000 | 8 | NIH | 5/12/2026 | $2,456,874 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01AI176665 | Mechanisms and manipulation of force dependent behavior in T cell biology | 000 | 4 | NIH | 2/23/2026 | $751,623 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R21AI194476 | Elucidating fungal and bacterial polymicrobial interactions during catheter-associated urinary tract infections | 000 | 2 | NIH | 7/8/2026 | $195,625 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | F31AI194736 | Defining the fungal-host interactions between the pathogenic yeast Cryptococcus neoformans and human microglia | 000 | 2 | NIH | 8/7/2026 | $50,114 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01EB038366 | Autonomous Hybrid Bioprinting of Hierarchical Perfusable Vascularized Liver Tissues | 000 | 1 | NIH | 3/2/2026 | $662,737 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R21TR006240 | MimicMaker: an integrated platform for identifying relevant mimics of T cell antigens | 000 | 1 | NIH | 5/4/2026 | $434,500 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R21AI199887 | Importation or local transmission? Genomics and serology to determine the sources of Plasmodium vivax and Plasmodium falciparum malaria in the Ethiopia highlands | 000 | 1 | NIH | 7/30/2026 | $434,500 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R21AG100901 | Pick's disease tau proteoforms via protein stapling | 000 | 1 | NIH | 6/18/2026 | $434,500 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R03AI196599 | Spatial Mapping to Detail the Role of Biomolecules in Governing Biofilm Organization and Resiliency to Stress in Pseudomonas aeruginosa Biofilms | 000 | 1 | NIH | 6/11/2026 | $158,000 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01DK140257 | Development of a Once-Weekly AND Glucose-Responsive Insulin Formulation | 000 | 2 | NIH | 7/7/2026 | $634,661 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01AI198251 | Intervention of Peptidoglycan Synthesis | 000 | 1 | NIH | 8/27/2026 | $709,532 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R21AI196489 | Species-specific Yeast RNAi Pesticides for Sand Fly Control | 000 | 1 | NIH | 4/3/2026 | $464,176 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R61AG104103 | OpenCARE: Open-Source Infrastructure for Evaluating Conversational AI in Dementia Care | 000 | 1 | NIH | 8/26/2026 | $582,492 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R21AI190342 | Targeting biofilm formation as a mechanism to enhance antibiotic efficacy against Mycobacterium avium and M. abscessus | 000 | 1 | NIH | 8/5/2026 | $434,500 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R00NS133484 | Immune regulation of spinal cord regeneration | 001 | 3 | NIH | 3/5/2026 | $24,900 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R00NS133484 | Immune regulation of spinal cord regeneration | 000 | 3 | NIH | 2/6/2026 | $224,100 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | F31AI197667 | Systematic Genetic Identification of Resistance Determinants and Fitness Modifiers in Malaria Parasites | 001 | 1 | NIH | 8/5/2026 | $0 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | F31AI197667 | Systematic Genetic Identification of Resistance Determinants and Fitness Modifiers in Malaria Parasites | 000 | 1 | NIH | 8/5/2026 | $50,114 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R35GM163614 | Determination of the Structure, Dynamics and Energetics of Enzyme Reactions | 000 | 1 | NIH | 8/5/2026 | $1,950,803 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | F31NS147858 | Determining the Role of Cellular Senescence in Chronic Demyelination and Remyelination | 001 | 1 | NIH | 8/7/2026 | $0 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | F31NS147858 | Determining the Role of Cellular Senescence in Chronic Demyelination and Remyelination | 000 | 1 | NIH | 8/7/2026 | $50,114 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | F31AA033533 | Improving the assessment of within-person impulsivity to understand processes of risk for alcohol-related negative consequences | 001 | 1 | NIH | 8/24/2026 | $0 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | F31AA033533 | Improving the assessment of within-person impulsivity to understand processes of risk for alcohol-related negative consequences | 000 | 1 | NIH | 8/24/2026 | $50,114 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R35GM161777 | Cellular Mechanisms Supporting Production of a Functional Proteome | 000 | 1 | NIH | 7/7/2026 | $632,000 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01AI201785 | Decoding the specificity of human T cell allorecognition | 000 | 1 | NIH | 8/20/2026 | $856,216 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R21AI203022 | Monoclonal Antibody-Conjugated Nanoparticles for Precision CMV Antiviral Deliver | 000 | 1 | NIH | 8/24/2026 | $237,000 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01AI200307 | Understanding the bladder inflammatory and immune responses to fungal catheter-associated urinary infections | 000 | 1 | NIH | 7/3/2026 | $614,655 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R21TW013266 | Unraveling the Role of Water Hyacinth in Modulating Schistosomiasis to Facilitate Scaling a Proven Disease Control Intervention | 000 | 1 | NIH | 8/31/2026 | $189,000 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | F31AA031894 | Combining ecological momentary assessment and qualitative methods to construct a theoretical model of acute alcohol use and non-suicidal self-injury | 001 | 2 | NIH | 9/3/2026 | $0 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | F31AA031894 | Combining ecological momentary assessment and qualitative methods to construct a theoretical model of acute alcohol use and non-suicidal self-injury | 000 | 2 | NIH | 8/19/2026 | $50,114 |
| | 2026 | 2026 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R00HD110604 | The Development of Youth Resilience to Neighborhood Disadvantage | 000 | 5 | NIH | 7/6/2026 | $232,418 |
|
