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 | Issue Date FY: 2025 ( Subtotal = $29,971,356 ) (Continued on the next page) |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01CA275423 | Engineered hybrid aging model for disease progression | 001 | 3 | NIH | 5/22/2025 | $46,271 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01CA275423 | Engineered hybrid aging model for disease progression | 000 | 3 | NIH | 4/22/2025 | $416,431 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01AI167284 | Repurposing Gram-positive Antibiotics for Gram-Negative Bacteria using Antibiotic Adjuvants | 001 | 4 | NIH | 8/12/2025 | $1,447,329 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | T32GM145773 | Chemistry-Biochemistry-Biology Interface (CBBI) Program at Notre Dame | 000 | 4 | NIH | 6/6/2025 | $321,270 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01CA280097 | Immunosuppression and Metabolic Rewiring in Tumor-infiltrating Neutrophils | 001 | 3 | NIH | 5/22/2025 | $36,219 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01CA280097 | Immunosuppression and Metabolic Rewiring in Tumor-infiltrating Neutrophils | 000 | 3 | NIH | 4/25/2025 | $325,977 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01GM148708 | New insights into extracellular signal transduction | 000 | 3 | NIH | 7/23/2025 | $328,650 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01NS135852 | CRCNS: Defining the role of astrogenesis in cortical folding | 001 | 3 | NIH | 8/6/2025 | $14,429 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01NS135852 | CRCNS: Defining the role of astrogenesis in cortical folding | 000 | 3 | NIH | 7/28/2025 | $129,858 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01MH128929 | An evidence-based family support program for parents and children: A theory-based intervention | 000 | 4 | NIH | 9/9/2025 | $639,084 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01AG071684 | A life course perspective on gut microbiome aging and health in a non-human primate model | 001 | 5 | NIH | 8/21/2025 | $49,959 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01AG071684 | A life course perspective on gut microbiome aging and health in a non-human primate model | 000 | 5 | NIH | 1/13/2025 | $562,056 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01CA252878 | CXCL5/CXCR2 axis as a therapeutic vulnerability of breast cancer metastasis to bone | 000 | 5 | NIH | 5/12/2025 | $357,994 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01CA267978 | 3H-pyrazolo[4,3-f]quinoline-containing compounds as selective and tunable protein kinase inhibitors | 001 | 4 | NIH | 6/19/2025 | $461,983 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | K23MH131753 | Neurobehavioral markers of positive valence systems in mothers with depression and young offspring | 005 | 4 | NIH | 8/11/2025 | $187,219 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R35GM143029 | Model-based inference and forecasting of co-circulating pathogen dynamics | 000 | 5 | NIH | 9/9/2025 | $391,250 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | DP1GM146256 | Decoding the regulation of protein folding by synonymous codon usage | 000 | 5 | NIH | 7/24/2025 | $1,095,500 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01AI155723 | Carbapenemase-Stable Carbapenem Antibiotics for Treatment of Multidrug-Resistant Acinetobacter baumannii Infections | 000 | 5 | NIH | 3/19/2025 | $773,298 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | F32HL165966 | Investigating the Critical Role of Glia In Peripheral Organ Development and Physiology | 001 | 3 | NIH | 8/21/2025 | $1,332 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | F32HL165966 | Investigating the Critical Role of Glia In Peripheral Organ Development and Physiology | 000 | 3 | NIH | 5/16/2025 | $78,892 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01CA262439 | Mitophagy-Mediated Cell Death in Mammary Tumorigenesis | 002 | 5 | NIH | 9/2/2025 | $73,042 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | K23AA029729 | Developing a modified brief alcohol-focused intervention tailored for patients with alcohol use disorder in opioid agonist treatment | 000 | 5 | NIH | 4/24/2025 | $153,820 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01CA262439 | Mitophagy-Mediated Cell Death in Mammary Tumorigenesis | 001 | 5 | NIH | 8/29/2025 | $398,607 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R35GM143055 | Engineering the Stem Cell Microenvironment for Lymphatic Regeneration | 000 | 5 | NIH | 5/13/2025 | $391,250 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01AG074570 | Chemical approaches to selectively target beta-rich amyloids | 001 | 5 | NIH | 6/5/2025 | $471,616 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01DK128805 | Understanding the role of catheter-associated protein deposition in the development of CAUTI | 001 | 5 | NIH | 5/21/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01DK128805 | Understanding the role of catheter-associated protein deposition in the development of CAUTI | 000 | 5 | NIH | 5/1/2025 | $372,846 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R21AI194476 | Elucidating fungal and bacterial polymicrobial interactions during catheter-associated urinary tract infections | 000 | 1 | NIH | 7/15/2025 | $234,750 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01HD116815 | Evaluating the effectiveness of the Common Elements Treatment Approach (CETA) in Peru: Mechanisms of individual and intergenerational change | 001 | 1 | NIH | 9/15/2025 | $88,172 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01HD116815 | Evaluating the effectiveness of the Common Elements Treatment Approach (CETA) in Peru: Mechanisms of individual and intergenerational change | 000 | 1 | NIH | 9/12/2025 | $517,978 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01DK140257 | Development of a Once-Weekly AND Glucose-Responsive Insulin Formulation | 000 | 1 | NIH | 9/1/2025 | $745,249 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | F31AA031894 | Combining ecological momentary assessment and qualitative methods to construct a theoretical model of acute alcohol use and non-suicidal self-injury | 001 | 1 | NIH | 9/9/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | F31AA031894 | Combining ecological momentary assessment and qualitative methods to construct a theoretical model of acute alcohol use and non-suicidal self-injury | 002 | 1 | NIH | 9/9/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | F31AA031894 | Combining ecological momentary assessment and qualitative methods to construct a theoretical model of acute alcohol use and non-suicidal self-injury | 000 | 1 | NIH | 9/9/2025 | $49,538 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R35GM158092 | Targeting Gram-Negative Bacteria for Antibacterial Strategies | 000 | 1 | NIH | 8/12/2025 | $414,725 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01AI189911 | Understanding Emerging artemisinin partner drug resistance in eastern Africa | 000 | 1 | NIH | 8/12/2025 | $705,896 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R35GM160331 | A Molecular Recognition Guidebook for Targeting Protein Loops with Covalent Ligands | 000 | 1 | NIH | 8/11/2025 | $387,857 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01AI176665 | Mechanisms and manipulation of force dependent behavior in T cell biology | 000 | 3 | NIH | 2/12/2025 | $735,147 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R21AI191060 | Bringing alloreactivity into focus with the lens of TCR cross-reactivity | 000 | 1 | NIH | 7/7/2025 | $459,439 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | P01AI127338 | Harnessing the Power of Experimental Genetic Crosses to Probe Drug Resistance in Malaria | 001 | 7 | NIH | 6/16/2025 | $2,465,529 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R21EB036776 | Supramolecular Engineering of Ultra-Long-Lasting GLP-1 Depots | 000 | 1 | NIH | 7/30/2025 | $430,375 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | F31AI194736 | Defining the fungal-host interactions between the pathogenic yeast Cryptococcus neoformans and human microglia | 001 | 1 | NIH | 8/19/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | F31AI194736 | Defining the fungal-host interactions between the pathogenic yeast Cryptococcus neoformans and human microglia | 000 | 1 | NIH | 8/19/2025 | $49,538 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01NS140152 | Endothelin signaling in neural stem cell homeostasis and remyelination | 000 | 1 | NIH | 8/6/2025 | $411,734 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | RF1MH133226 | Leveraging Noninvasive Transcutaneous Vagus Nerve Stimulation and Smartphone Technology to Reduce Suicidal Behaviors and Suicide Among Highly Vulnerable Adolescents | 000 | 4 | NIH | 8/12/2025 | $1,312,589 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | RF1MH133226 | Leveraging Noninvasive Transcutaneous Vagus Nerve Stimulation and Smartphone Technology to Reduce Suicidal Behaviors and Suicide Among Highly Vulnerable Adolescents | 001 | 4 | NIH | 9/17/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01EY034493 | Elucidating and bypassing molecular mechanisms that suppress Muller glia-dependent regeneration of cones in two zebrafish models of chronic retinal damage | 000 | 3 | NIH | 2/14/2025 | $555,742 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01AI188782 | pH-Dependent Switching of ESX-1 Substrates in Mycobacterial Pathogenesis | 000 | 1 | NIH | 8/11/2025 | $659,122 |
| | 2025 | 2025 | UNIVERSITY OF NOTRE DAME DU LAC | 940 GRACE HALL | NOTRE DAME | IN | 46556-5708 | ST JOSEPH | USA | R01CA297220 | Developing isoform-selective Hsp90 inhibitors for monotherapy and enhanced immunotherapy against lethal prostate cancer | 000 | 1 | NIH | 6/10/2025 | $551,601 |
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