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Miniaturized No-Moving-Parts Scanning Light Endoscope

Award Number: R21EB037917
ORGANIZATION: NATIONAL INSTITUTE Of BIOMEDICAL IMAGING & BIOENGINEERING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 06/06/2026
PERIOD OF PERFORMANCE END DATE: 04/30/2029

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Miniaturized No-Moving-Parts Scanning Light Endoscope - Project Summary This project aims to develop a new type of scanning light endoscope that will facilitate high-speed three-dimensional (3D) deep imaging into live biological systems. This innovative approach allows for optical scanning along the path of light, which is essential for volumetric imaging but absent in traditional surface-examining endoscopy. The team will leverage the recent improvement in potassium tantalate niobite (KTN) crystal growth to create a compact scanner utilizing KTN’s special electro-optic effects. This new scanner will enable rapid optical focusing across a volume approximately with a microsecond response time, following any desired 3D path, all without mechanical or moving parts—a much-anticipated advancement for clinical applications. The team will conduct physical modeling to simulate and understand the complex interactions among various physical processes occurring simultaneously within KTN crystals. Armed with this insight, they will design and manufacture prototype endoscopes, prepare the device for preclinical use, and assess its performance in ex-vivo organs and living animals.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $247,500 )
2026	2026	THE GENERAL HOSPITAL CORPORATION	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	1	6/9/2026	NEW	$247,500
														Subtotal = $247,500

Grand Total All Awards = $247,500

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Miniaturized No-Moving-Parts Scanning Light Endoscope

Award Number: R21EB037917

ORGANIZATION: NATIONAL INSTITUTE Of BIOMEDICAL IMAGING & BIOENGINEERING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 06/06/2026

PERIOD OF PERFORMANCE END DATE: 04/30/2029

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