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Investigating the contribution of extended high-frequency hearing loss to poor speech-in-noise perception in clinically normal hearing children and young adults.

Award Number: R21DC020242
ORGANIZATION: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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People with clinically defined normal hearing frequently report difficulty hearing in challenging environments. They often leave audiology clinics with no diagnosis to explain the difficulty they experience listening in noise. Studies in adults demonstrate that extended high frequency (EHF; > 8 kHz) hearing, beyond the currently tested range of clinical audiometry, contributes to speech perception in noise. Young children are the most sensitive to EHFs, and this sensitivity is progressively lost throughout the remainder of life. Previous studies found a significant relationship between EHF hearing loss (EHFHL) and difficulty understanding speech-in-noise (SiN) in adults with clinically normal hearing. However, to our knowledge, no studies have investigated this relationship in typically-developing, normal-hearing children and youth. The present study aims to address this gap by investigating the association between EHFHL and impaired SiN perception in children and young adults (8 to 30 y/o) with clinically normal hearing (= 20 dB HL, 0.25 - 0.8 kHz). There are three specific aims. In Aim 1 we will establish the relationship between EHFHL and subjective reports of listening difficulties using standard (0.25-8 kHz) and EHF (9 - 16 kHz) audiometry. The adult and child versions of the Speech, Spatial and Qualities (SSQ) questionnaire will measure self- and parent-reported difficulty listening in noise. In Aim 2 we will determine the impact of EHFHL on the perception of spatial speech using the sound-field digits-in-noise (sfDIN) test. In Aim 3, we will evaluate low-frequency correlates of EHFHL and their possible effect on SiN. Objective (chirp transient- evoked otoacoustic emissions) and behavioral (spectro-temporal modulation task) measures of supra-threshold hearing will be used to determine whether supra-threshold deficits at standard frequencies (= 8 kHz) account for associations between EHFHL and SiN that have been observed for adults and are predicted for children. Outcomes of these experiments will enhance our understanding of the impact of EHFHL on communication abilities of children. If EHFHL contributes to the difficulty children experience in challenging environments, as we hypothesize, then including EHF hearing assessment in an audiologic test battery could identify susceptible individuals and in turn lead to prevention and early intervention for hearing loss.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $99,167 )
2024	2024	UNIVERSITY OF CINCINNATI	2600 CLIFTON AVE	CINCINNATI	OH	45220	HAMILTON	USA	Research Related to Deafness and Communication Disorders	002	4	3/29/2024	NON-COMPETING CONTINUATION	$150,607
2024	2023	UNIVERSITY OF CINCINNATI	2600 CLIFTON AVE	CINCINNATI	OH	45220	HAMILTON	USA	Research Related to Deafness and Communication Disorders	001	3	3/5/2024	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$140,953
2024	2023	CHILDRENS HOSPITAL MEDICAL CENTER	3333 BURNET AVE	CINCINNATI	OH	45229	HAMILTON	USA	Research Related to Deafness and Communication Disorders	000	2	3/5/2024	NON-COMPETING CONTINUATION	-$192,393
														Subtotal = $99,167

Issue Date FY: 2023 ( Subtotal = $215,998 )
2023	2023	CHILDRENS HOSPITAL MEDICAL CENTER	3333 BURNET AVE	CINCINNATI	OH	45229	HAMILTON	USA	Research Related to Deafness and Communication Disorders	000	2	3/14/2023	NON-COMPETING CONTINUATION	$215,998
														Subtotal = $215,998

Issue Date FY: 2022 ( Subtotal = $209,211 )
2022	2022	CHILDREN'S HOSPITAL MEDICAL CENTER	3333 BURNET AVE	CINCINNATI	OH	45229	HAMILTON	USA	Research Related to Deafness and Communication Disorders	000	1	3/25/2022	NEW	$209,211
														Subtotal = $209,211

Grand Total All Awards = $524,376

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Investigating the contribution of extended high-frequency hearing loss to poor speech-in-noise perception in clinically normal hearing children and young adults.

Award Number: R21DC020242

ORGANIZATION: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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