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 | Issue Date FY: 2025 ( Subtotal = $168,081,616 ) (Continued on the next page) |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL168790 | Mechanisms governing the differentiation and maintenance of atrial identity | 001 | 3 | NIH | 7/9/2025 | $63,718 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL168790 | Mechanisms governing the differentiation and maintenance of atrial identity | 000 | 3 | NIH | 4/10/2025 | $573,472 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AR083368 | Development and optimization of skeletal muscle delivery vehicles | 000 | 2 | NIH | 7/10/2025 | $472,543 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | K08GM148957 | Mechanisms of cardiomyocyte dysfunction in pediatric septic shock | 000 | 3 | NIH | 1/24/2025 | $192,024 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL169242 | Allogeneic virus-specific T-cell therapy after hematopoietic stem cell transplant: determinants of treatment success and failure | 000 | 2 | NIH | 5/7/2025 | $646,249 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F30AI157421 | Silencer Control of T cell Homeostasis | 001 | 4 | NIH | 8/4/2025 | $564 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F30AI157421 | Silencer Control of T cell Homeostasis | 000 | 4 | NIH | 10/31/2024 | $53,974 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AR084717 | Natural history and validation of surrogate biomarkers and patient-reported outcomes for SJIA-LD | 000 | 2 | NIH | 6/26/2025 | $170,878 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F31HL172346 | Effects of early Retinoic Acid signaling on valve development | 001 | 2 | NIH | 7/9/2025 | $564 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F31HL172346 | Effects of early Retinoic Acid signaling on valve development | 000 | 2 | NIH | 1/20/2025 | $41,915 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL105924 | Thrombospondin 4 regulates adaptive ER stress responseRenewal - Resubmission - 1 | 003 | 14 | NIH | 7/31/2025 | $59,892 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL156852 | Innate immune response signaling in cardiac injury healing | 001 | 4 | NIH | 8/12/2025 | $60,517 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL156852 | Innate immune response signaling in cardiac injury healing | 000 | 4 | NIH | 11/29/2024 | $544,642 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R37CA291896 | Targeting Polyamine Metabolism in Relapsed Acute Myeloid Leukemia Stem Cells | 000 | 1 | NIH | 9/10/2025 | $530,106 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21AI188683 | Contribution of adipose tissue immune cells to Influenza pathogenesis | 000 | 1 | NIH | 8/18/2025 | $240,750 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21HD117015 | Quantifying the impact of hyperglycemia on embryonic metabolism and development in C. elegans. | 000 | 1 | NIH | 7/18/2025 | $474,878 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL180559 | The Impact of SLC26A9 on Response to CFTR Correction | 000 | 1 | NIH | 8/15/2025 | $727,575 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21HD115788 | Evaluating EHR-based Prediction of Obesity using WHO Weight Velocity Standards and Peak BMI | 000 | 1 | NIH | 8/29/2025 | $456,914 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21AI190243 | A VP4-Based Pseudovirus Nanoparticle Rotavirus Vaccine for Oral Immunization | 000 | 1 | NIH | 9/3/2025 | $458,250 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F31DE035754 | Investigating the role of ESRP2 in craniofacial development using the cleft primary palate (cpp) avian model. | 002 | 1 | NIH | 8/18/2025 | $0 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21EB036699 | A Deep Learning-based Assessment Pipeline for Peripherally Inserted Central Catheters (PICCs) on Pediatric Radiographs | 000 | 1 | NIH | 8/13/2025 | $642,000 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F31DE035754 | Investigating the role of ESRP2 in craniofacial development using the cleft primary palate (cpp) avian model. | 001 | 1 | NIH | 8/18/2025 | $0 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F30AI194437 | Dissecting an IL4Ra-dependent neuroimmune circuit in eosinophilic esophagitis | 000 | 1 | NIH | 8/15/2025 | $42,479 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F31DE035754 | Investigating the role of ESRP2 in craniofacial development using the cleft primary palate (cpp) avian model. | 000 | 1 | NIH | 8/18/2025 | $50,324 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R00AI175483 | Regulation of the MAVS Signalosome by RNA and RNA-binding Proteins | 000 | 3 | NIH | 7/7/2025 | $249,000 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R03ES037996 | Enhancing the Sustainability and Impact of Geomarker Assessment Tools for Research | 000 | 1 | NIH | 8/14/2025 | $481,500 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | U24HG013078 | CisBP and CisBP-RNA: web resources for protein-DNA and protein-RNA binding models | 000 | 2 | NIH | 6/9/2025 | $544,784 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL137766 | Molecular Mechanisms of Atrial Development and Regeneration | 001 | 7 | NIH | 8/4/2025 | $57,883 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL142217 | Cardiac Fibroblasts in Postnatal Development and Adult Injury Response | 002 | 7 | NIH | 7/2/2025 | $785,229 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL137766 | Molecular Mechanisms of Atrial Development and Regeneration | 000 | 7 | NIH | 1/27/2025 | $520,941 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01CA287486 | HPV and host factors in juvenile onset recurrent respiratory papillomatosis | 000 | 2 | NIH | 6/18/2025 | $446,728 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS132504 | Advancing CNS drug delivery via epigenetic modulation | 001 | 3 | NIH | 8/19/2025 | $131,265 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS132504 | Advancing CNS drug delivery via epigenetic modulation | 000 | 3 | NIH | 1/27/2025 | $511,676 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL172914 | Cellular determinants of responsiveness to mTOR inhibitors in LAM | 000 | 1 | NIH | 1/30/2025 | $739,236 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01CA278834 | The role of DNAJB1-PKAc-β-catenin axis in fibrolamellar HCC | 001 | 3 | NIH | 5/28/2025 | $63,730 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01CA278834 | The role of DNAJB1-PKAc-β-catenin axis in fibrolamellar HCC | 000 | 3 | NIH | 3/4/2025 | $573,569 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R33GM151734 | Biobank of small extracellular vesicles for pediatric sepsis | 000 | 3 | NIH | 7/1/2025 | $516,797 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R33GM151703 | Leveraging multi-omics to maximize the scientific value of pediatric sepsis biorepository and advance patient endotyping | 000 | 3 | NIH | 7/1/2025 | $705,050 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21AI191085 | Development and application of pediatric-specific blood transcriptional modules across diverse geographical settings through public data mining | 000 | 1 | NIH | 2/25/2025 | $286,791 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R35HL177131 | Establishing lifelong trajectories of pulmonary health | 001 | 1 | NIH | 7/14/2025 | -$643,515 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21CA300922 | Pancancer discovery and exploration of shared splicing neoantigens | 000 | 1 | NIH | 2/24/2025 | $225,101 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | U01DK134976 | Cincinnati Children's Clinical Center for Targeting the Pathophysiology of Youth-Onset Type 2 Diabetes | 000 | 3 | NIH | 2/14/2025 | $751,761 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R35HL177131 | Establishing lifelong trajectories of pulmonary health | 000 | 1 | NIH | 3/11/2025 | $915,924 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS099068 | Binding of Epstein Barr Virus EBNA2 Unifies Multiple Sclerosis Genetic Mechanisms | 001 | 8 | NIH | 4/9/2025 | $626,014 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01CA271455 | Dissecting innate immune signaling in pre-leukemia evolution | 001 | 4 | NIH | 5/23/2025 | $63,825 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01CA271455 | Dissecting innate immune signaling in pre-leukemia evolution | 000 | 4 | NIH | 3/5/2025 | $574,418 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | UG3AI190045 | Antibiotics, innate immunity, and dysbiosis in pediatric urticarial reactions | 000 | 1 | NIH | 7/16/2025 | $401,250 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AI184466 | Naive CD8 T cell functional heterogeneity | 000 | 1 | NIH | 3/19/2025 | $639,084 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21MD019192 | Association of DNA Methylation and Stress in Immigrants | 001 | 2 | NIH | 3/31/2025 | $240,750 |
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