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 | Issue Date FY: 2025 ( Subtotal = $181,424,041 ) (Continued on the next page) |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | U01AI159087 | Multi-omics of the Frequent Exacerbator Asthmatic | 000 | 5 | NIH | 4/14/2025 | $452,000 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | U01HL133883 | Realizing Effectiveness Across Continents with Hydroxyurea(REACH): A Phase I/II Pilot Study of Hyroxyurea for Children with Sickle Cell Anemia | 002 | 9 | NIH | 9/14/2025 | $196,803 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL156860 | Epigenetic Regulation of the Maturation and Function of Lung Epithelium by the SWI/SNF Proteins ARID1A and ARID1B. | 001 | 5 | NIH | 7/15/2025 | $357,750 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | U01HL133883 | Realizing Effectiveness Across Continents with Hydroxyurea(REACH): A Phase I/II Pilot Study of Hyroxyurea for Children with Sickle Cell Anemia | 001 | 9 | NIH | 9/13/2025 | $282,506 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL158100 | Effect of reproductive history on longitudinal change in cardiac, vascular and lipid parameters | 001 | 4 | NIH | 8/12/2025 | $68,639 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL158100 | Effect of reproductive history on longitudinal change in cardiac, vascular and lipid parameters | 000 | 4 | NIH | 12/3/2024 | $617,753 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R61NS138647 | Novel Biologics to Ablate Choroid Plexus for the Treatment of Neonatal Hydrocephalus | 001 | 2 | NIH | 8/14/2025 | $379,463 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R35GM155165 | Translational approaches to unravel organ-specific microvascular endothelial responses in sepsis. | 000 | 2 | NIH | 4/17/2025 | $401,250 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R03TR004974 | A Novel Ultrasound Score to Improve the Assessment of Joint Inflammation in Children with Chronic Musculoskeletal Pain | 000 | 1 | NIH | 8/27/2025 | $162,000 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DK140321 | The Roles of MRP9 in cholangiocyte metabolism | 000 | 1 | NIH | 7/1/2025 | $806,192 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21HD119083 | Microglia-Integrated Brain Organoids for Gaucher Disease Modeling and Therapeutic Discovery | 000 | 1 | NIH | 8/1/2025 | $441,375 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R03DK141897 | The transcriptional, regulatory, and spatially defined changes from mid to late gestation in a non-human primate model | 000 | 1 | NIH | 8/28/2025 | $240,978 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21AI190579 | Cell specific roles of CD153 and CD30 in regulation of immune responses | 000 | 1 | NIH | 7/29/2025 | $441,375 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R61NS138554 | SapC-based Brain-targeting Delivery of Long-acting Enzymes for Neuronopathic Gaucher Disease Therapy | 000 | 1 | NIH | 7/22/2025 | $803,958 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS141307 | Cell type-specific epigenetic control of brain function | 000 | 1 | NIH | 7/24/2025 | $579,294 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | K99HL179261 | The role of matrifibrocytes in a fibrotic-like response during myxomatous heart valve disease progression | 000 | 1 | NIH | 8/6/2025 | $118,632 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F30HD117460 | Contribution of adipocyte inflammation to parturition timing | 000 | 1 | NIH | 7/21/2025 | $42,479 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F30HD117460 | Contribution of adipocyte inflammation to parturition timing | 001 | 1 | NIH | 7/21/2025 | $0 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HD093754 | Cognitive Outcome Measures in School Age Children with Down Syndrome (ECODS) | 001 | 7 | NIH | 6/30/2025 | $916,624 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F30AI194437 | Dissecting an IL4Ra-dependent neuroimmune circuit in eosinophilic esophagitis | 000 | 1 | NIH | 8/15/2025 | $42,479 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R03ES037996 | Enhancing the Sustainability and Impact of Geomarker Assessment Tools for Research | 000 | 1 | NIH | 8/14/2025 | $481,500 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | K08CA237753 | Targeting MBNL1-mediated alternative splicing in MLL-fusion leukemia | 000 | 5 | NIH | 2/13/2025 | $196,112 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HD068524 | Molecular signaling in uterine receptivity to implantation | 001 | 13 | NIH | 4/24/2025 | $43,906 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HD068524 | Molecular signaling in uterine receptivity to implantation | 000 | 13 | NIH | 3/11/2025 | $395,158 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AI153442 | An experimentally-refined, dynamic gene regulatory network model of T-cell memory | 000 | 5 | NIH | 2/13/2025 | $633,135 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL131012 | Regional monitoring of CF lung disease after changes in mechanical airway-clearance treatment | 002 | 8 | NIH | 9/5/2025 | $80,051 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL131012 | Regional monitoring of CF lung disease after changes in mechanical airway-clearance treatment | 001 | 8 | NIH | 4/7/2025 | $720,465 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21HL179437 | Intein technology to deliver CFTR to CF airway using AAV | 000 | 1 | NIH | 8/27/2025 | $441,375 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AI184441 | Dendritic cell intrinsic UPR is critical for pathogen specific Th17 responses | 000 | 1 | NIH | 8/28/2025 | $3,147,392 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21EB036699 | A Deep Learning-based Assessment Pipeline for Peripherally Inserted Central Catheters (PICCs) on Pediatric Radiographs | 000 | 1 | NIH | 8/13/2025 | $642,000 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21AI188683 | Contribution of adipose tissue immune cells to Influenza pathogenesis | 000 | 1 | NIH | 8/18/2025 | $240,750 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F31DE035754 | Investigating the role of ESRP2 in craniofacial development using the cleft primary palate (cpp) avian model. | 002 | 1 | NIH | 8/18/2025 | $0 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F31DE035754 | Investigating the role of ESRP2 in craniofacial development using the cleft primary palate (cpp) avian model. | 001 | 1 | NIH | 8/18/2025 | $0 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F31DE035754 | Investigating the role of ESRP2 in craniofacial development using the cleft primary palate (cpp) avian model. | 000 | 1 | NIH | 8/18/2025 | $50,324 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R00AI175483 | Regulation of the MAVS Signalosome by RNA and RNA-binding Proteins | 000 | 3 | NIH | 7/7/2025 | $249,000 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HD094862 | Dosing and Pilot Efficacy of 2'-Fucosyllactose in Inflammatory Bowel Disease | 002 | 7 | NIH | 6/26/2025 | $677,278 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01CA278834 | The role of DNAJB1-PKAc-β-catenin axis in fibrolamellar HCC | 001 | 3 | NIH | 5/28/2025 | $63,730 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01CA278834 | The role of DNAJB1-PKAc-β-catenin axis in fibrolamellar HCC | 000 | 3 | NIH | 3/4/2025 | $573,569 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01CA271455 | Dissecting innate immune signaling in pre-leukemia evolution | 001 | 4 | NIH | 5/23/2025 | $63,825 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01CA271455 | Dissecting innate immune signaling in pre-leukemia evolution | 000 | 4 | NIH | 3/5/2025 | $574,418 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R35HL177131 | Establishing lifelong trajectories of pulmonary health | 000 | 1 | NIH | 3/11/2025 | $915,924 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21AI191085 | Development and application of pediatric-specific blood transcriptional modules across diverse geographical settings through public data mining | 000 | 1 | NIH | 2/25/2025 | $286,791 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS099068 | Binding of Epstein Barr Virus EBNA2 Unifies Multiple Sclerosis Genetic Mechanisms | 001 | 8 | NIH | 4/9/2025 | $626,014 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21CA300922 | Pancancer discovery and exploration of shared splicing neoantigens | 000 | 1 | NIH | 2/24/2025 | $225,101 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R35HL177131 | Establishing lifelong trajectories of pulmonary health | 001 | 1 | NIH | 7/14/2025 | -$643,515 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21MD019192 | Association of DNA Methylation and Stress in Immigrants | 001 | 2 | NIH | 3/31/2025 | $240,750 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DK135478 | Organoid-guided Precision Hepatology for Steatohepatitis | 000 | 2 | NIH | 2/19/2025 | $530,803 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | UG3AI190045 | Antibiotics, innate immunity, and dysbiosis in pediatric urticarial reactions | 000 | 1 | NIH | 7/16/2025 | $401,250 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AI184466 | Naive CD8 T cell functional heterogeneity | 000 | 1 | NIH | 3/19/2025 | $639,084 |
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