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 | Issue Date FY: 2025 ( Subtotal = $181,424,041 ) (Continued on the next page) |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | U01HL133883 | Realizing Effectiveness Across Continents with Hydroxyurea(REACH): A Phase I/II Pilot Study of Hyroxyurea for Children with Sickle Cell Anemia | 001 | 9 | NIH | 9/13/2025 | $282,506 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL156860 | Epigenetic Regulation of the Maturation and Function of Lung Epithelium by the SWI/SNF Proteins ARID1A and ARID1B. | 001 | 5 | NIH | 7/15/2025 | $357,750 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | U01DA055342 | 4/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) Consortium | 000 | 5 | NIH | 8/7/2025 | $300,000 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | U01HL133883 | Realizing Effectiveness Across Continents with Hydroxyurea(REACH): A Phase I/II Pilot Study of Hyroxyurea for Children with Sickle Cell Anemia | 000 | 9 | NIH | 9/11/2025 | $500,339 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R61MH135994 | ADHD PreSMART: ADHD PreSMA Response inhibition Therapy | 000 | 2 | NIH | 8/27/2025 | $488,668 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | K01DK135647 | Microbial regulation of intestinal tuft cell homeostasis | 000 | 3 | NIH | 12/10/2024 | $140,271 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NR020781 | A socio-ecological approach for improving self-management in adolescents with SCD | 000 | 3 | NIH | 7/21/2025 | $657,031 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL168790 | Mechanisms governing the differentiation and maintenance of atrial identity | 000 | 3 | NIH | 4/10/2025 | $573,472 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | K99HL179261 | The role of matrifibrocytes in a fibrotic-like response during myxomatous heart valve disease progression | 000 | 1 | NIH | 8/6/2025 | $118,632 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HD094862 | Dosing and Pilot Efficacy of 2'-Fucosyllactose in Inflammatory Bowel Disease | 002 | 7 | NIH | 6/26/2025 | $677,278 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F31DE035754 | Investigating the role of ESRP2 in craniofacial development using the cleft primary palate (cpp) avian model. | 001 | 1 | NIH | 8/18/2025 | $0 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F31DE035754 | Investigating the role of ESRP2 in craniofacial development using the cleft primary palate (cpp) avian model. | 000 | 1 | NIH | 8/18/2025 | $50,324 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R00AI175483 | Regulation of the MAVS Signalosome by RNA and RNA-binding Proteins | 000 | 3 | NIH | 7/7/2025 | $249,000 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21EB036699 | A Deep Learning-based Assessment Pipeline for Peripherally Inserted Central Catheters (PICCs) on Pediatric Radiographs | 000 | 1 | NIH | 8/13/2025 | $642,000 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21AI188683 | Contribution of adipose tissue immune cells to Influenza pathogenesis | 000 | 1 | NIH | 8/18/2025 | $240,750 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F31DE035754 | Investigating the role of ESRP2 in craniofacial development using the cleft primary palate (cpp) avian model. | 002 | 1 | NIH | 8/18/2025 | $0 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21HD115788 | Evaluating EHR-based Prediction of Obesity using WHO Weight Velocity Standards and Peak BMI | 000 | 1 | NIH | 8/29/2025 | $456,914 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R00HL169742 | Left-right asymmetry and PITX2 in atrial fibrillation | 000 | 3 | NIH | 8/7/2025 | $249,000 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21AI190243 | A VP4-Based Pseudovirus Nanoparticle Rotavirus Vaccine for Oral Immunization | 000 | 1 | NIH | 9/3/2025 | $458,250 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HD068524 | Molecular signaling in uterine receptivity to implantation | 000 | 13 | NIH | 3/11/2025 | $395,158 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HD068524 | Molecular signaling in uterine receptivity to implantation | 001 | 13 | NIH | 4/24/2025 | $43,906 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AI153442 | An experimentally-refined, dynamic gene regulatory network model of T-cell memory | 000 | 5 | NIH | 2/13/2025 | $633,135 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | K08CA237753 | Targeting MBNL1-mediated alternative splicing in MLL-fusion leukemia | 000 | 5 | NIH | 2/13/2025 | $196,112 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21HD117015 | Quantifying the impact of hyperglycemia on embryonic metabolism and development in C. elegans. | 000 | 1 | NIH | 7/18/2025 | $474,878 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL180559 | The Impact of SLC26A9 on Response to CFTR Correction | 000 | 1 | NIH | 8/15/2025 | $727,575 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HD093754 | Cognitive Outcome Measures in School Age Children with Down Syndrome (ECODS) | 001 | 7 | NIH | 6/30/2025 | $916,624 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R03ES037996 | Enhancing the Sustainability and Impact of Geomarker Assessment Tools for Research | 000 | 1 | NIH | 8/14/2025 | $481,500 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F30AI194437 | Dissecting an IL4Ra-dependent neuroimmune circuit in eosinophilic esophagitis | 000 | 1 | NIH | 8/15/2025 | $42,479 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS099068 | Binding of Epstein Barr Virus EBNA2 Unifies Multiple Sclerosis Genetic Mechanisms | 001 | 8 | NIH | 4/9/2025 | $626,014 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21CA300922 | Pancancer discovery and exploration of shared splicing neoantigens | 000 | 1 | NIH | 2/24/2025 | $225,101 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R35HL177131 | Establishing lifelong trajectories of pulmonary health | 001 | 1 | NIH | 7/14/2025 | -$643,515 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R35HL177131 | Establishing lifelong trajectories of pulmonary health | 000 | 1 | NIH | 3/11/2025 | $915,924 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21AI191085 | Development and application of pediatric-specific blood transcriptional modules across diverse geographical settings through public data mining | 000 | 1 | NIH | 2/25/2025 | $286,791 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R33GM151734 | Biobank of small extracellular vesicles for pediatric sepsis | 000 | 3 | NIH | 7/1/2025 | $516,797 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R33GM151703 | Leveraging multi-omics to maximize the scientific value of pediatric sepsis biorepository and advance patient endotyping | 000 | 3 | NIH | 7/1/2025 | $705,050 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21MD019192 | Association of DNA Methylation and Stress in Immigrants | 001 | 2 | NIH | 3/31/2025 | $240,750 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R37CA302422 | A Tailored Medication Adherence-Promotion Intervention for Adolescents and Young Adults with Cancer | 000 | 1 | NIH | 8/27/2025 | $717,786 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21AI187803 | Transcriptional mechanisms of chronic inflammation in genetically diverse tissue macrophages | 000 | 1 | NIH | 8/12/2025 | $441,375 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL131012 | Regional monitoring of CF lung disease after changes in mechanical airway-clearance treatment | 001 | 8 | NIH | 4/7/2025 | $720,465 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AI184441 | Dendritic cell intrinsic UPR is critical for pathogen specific Th17 responses | 000 | 1 | NIH | 8/28/2025 | $3,147,392 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL131012 | Regional monitoring of CF lung disease after changes in mechanical airway-clearance treatment | 002 | 8 | NIH | 9/5/2025 | $80,051 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21HL179437 | Intein technology to deliver CFTR to CF airway using AAV | 000 | 1 | NIH | 8/27/2025 | $441,375 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AI184466 | Naive CD8 T cell functional heterogeneity | 000 | 1 | NIH | 3/19/2025 | $639,084 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | UG3AI190045 | Antibiotics, innate immunity, and dysbiosis in pediatric urticarial reactions | 000 | 1 | NIH | 7/16/2025 | $401,250 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DK140321 | The Roles of MRP9 in cholangiocyte metabolism | 000 | 1 | NIH | 7/1/2025 | $806,192 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R03DK141897 | The transcriptional, regulatory, and spatially defined changes from mid to late gestation in a non-human primate model | 000 | 1 | NIH | 8/28/2025 | $240,978 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL176565 | Comparative study of gene regulatory and structural mechanisms in Lamin-related cardiomyopathy | 000 | 1 | NIH | 8/27/2025 | $511,987 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R03TR004974 | A Novel Ultrasound Score to Improve the Assessment of Joint Inflammation in Children with Chronic Musculoskeletal Pain | 000 | 1 | NIH | 8/27/2025 | $162,000 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21HD119083 | Microglia-Integrated Brain Organoids for Gaucher Disease Modeling and Therapeutic Discovery | 000 | 1 | NIH | 8/1/2025 | $441,375 |
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