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 | Issue Date FY: 2025 ( Subtotal = $41,661,447 ) (Continued on the next page) |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DK133145 | Diabetic Memory in Hematopoietic Stem Cells | 000 | 3 | NIH | 1/1/2025 | $399,184 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HD114702 | Food-based Randomized trial for Enhancing Support of Hospitalized children and their families (FRESH) | 000 | 1 | NIH | 12/20/2024 | $690,147 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21AI183058 | Systems analysis of immune responses to Norovirus infection in a human challenge model. | 000 | 1 | NIH | 11/26/2024 | $233,528 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R35HL177125 | The microenvironment in bone marrow hematopoiesis | 000 | 1 | NIH | 1/1/2025 | $1,123,357 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DK134646 | RNA silencing machinery in extracellular vesicle-mediated immunometabolic regulation | 000 | 2 | NIH | 11/25/2024 | $529,898 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | UM1HL172717 | Pediatric Heart Network Joint Heart Program Consortium | 000 | 2 | NIH | 12/25/2024 | $399,769 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL167200 | Role of apoE in HDL-mediated enhanced survival of human regulatory T-cells | 000 | 3 | NIH | 12/20/2024 | $596,375 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HD116852 | The role of HLA-C in chronic chorioamnionitis | 000 | 1 | NIH | 12/20/2024 | $630,107 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS125316 | Understanding the Impact of Youth Onset Obesity and Type 2 Diabetes on the Neurovascular Unit | 000 | 4 | NIH | 1/27/2025 | $333,869 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS125316 | Understanding the Impact of Youth Onset Obesity and Type 2 Diabetes on the Neurovascular Unit | 000 | 4 | NIH | 1/27/2025 | $80,587 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL171221 | Developing DWORF gene therapy to treat heart failure and muscular dystrophy | 000 | 2 | NIH | 12/5/2024 | $534,463 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01MH122415 | Longitudinal Examination of Sluggish Cognitive Tempo and Internalizing Psychopathology in Adolescence | 000 | 5 | NIH | 12/5/2024 | $636,720 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R35GM156830 | Post-transcriptional regulation of stem and progenitor cell function | 000 | 1 | NIH | 1/20/2025 | $380,546 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F31HL172346 | Effects of early Retinoic Acid signaling on valve development | 000 | 2 | NIH | 1/20/2025 | $41,915 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS132504 | Advancing CNS drug delivery via epigenetic modulation | 000 | 3 | NIH | 1/27/2025 | $511,676 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL137766 | Molecular Mechanisms of Atrial Development and Regeneration | 000 | 7 | NIH | 1/27/2025 | $520,941 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F31HL178081 | Characterization of Nrac, a Novel Cardiac and Adipose Enriched Microprotein | 000 | 1 | NIH | 12/16/2024 | $41,915 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS140460 | Glial Origin and Signaling in Medulloblastoma | 000 | 1 | NIH | 11/27/2024 | $604,852 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01CA278756 | Rational targeting of Cdc42 to benefit immunotherapy | 000 | 2 | NIH | 11/27/2024 | $534,962 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AI123176 | Innate mechanisms of regulation of Th17 responses | 000 | 9 | NIH | 12/17/2024 | $462,691 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | K23MH125138 | A Family Navigator Intervention to Improve ADHD- Related Treatment Adherence (I2-ART) for Minority Children | 000 | 5 | NIH | 12/9/2024 | $187,176 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL166245 | Defining PRC2 complex epigenomic control in alveolar progenitor cells | 000 | 3 | NIH | 11/18/2024 | $523,395 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | K23DC022304 | Neural Speech Tracking in Infants: Associations with Hearing, Environment, and Language | 000 | 1 | NIH | 11/21/2024 | $162,448 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F30AI188599 | Mechanisms of CD8+ T cell-induced Innate Immune Activation | 001 | 1 | NIH | 11/16/2024 | $0 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | K01DK135647 | Microbial regulation of intestinal tuft cell homeostasis | 000 | 3 | NIH | 12/10/2024 | $140,271 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R37CA225807 | Pathogenic Role of Foxl1+ Hepatic Progenitor Cells in Fibrotic Liver Disease | 002 | 7 | NIH | 11/21/2024 | $333,118 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F30AI188599 | Mechanisms of CD8+ T cell-induced Innate Immune Activation | 000 | 1 | NIH | 11/16/2024 | $41,915 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DE033890 | Molecular Regulation of Palate Development | 000 | 2 | NIH | 12/3/2024 | $597,758 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21AI191085 | Development and application of pediatric-specific blood transcriptional modules across diverse geographical settings through public data mining | 000 | 1 | NIH | 2/25/2025 | $286,791 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21CA300922 | Pancancer discovery and exploration of shared splicing neoantigens | 000 | 1 | NIH | 2/24/2025 | $225,101 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01FD007267 | Abatacept for the treatment of Common Variable Immunodeficiency with Interstitial Lung Disease (ABCVILD) IND #152820 9/2/20 | 002 | 3 | FDA | 3/21/2025 | $0 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DK091566 | Genetic basis of virus induced Biliary Atresia | 000 | 10 | NIH | 3/5/2025 | $637,505 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01FD007267 | Abatacept for the treatment of Common Variable Immunodeficiency with Interstitial Lung Disease (ABCVILD) IND #152820 9/2/20 | 001 | 3 | FDA | 3/5/2025 | $0 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R35HL171346 | Transcriptional and epigenetic mechanisms of alveologenesis and re-alveologenesis | 000 | 2 | NIH | 3/27/2025 | $1,010,116 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01CA271455 | Dissecting innate immune signaling in pre-leukemia evolution | 000 | 4 | NIH | 3/5/2025 | $574,418 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21HD118147 | Neural Crest Regulation of Embryonic Calcium Uptake | 000 | 1 | NIH | 2/20/2025 | $200,625 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | U01CA298630 | Cell-Cell Signaling Driving HPV-Induced Respiratory Disease and Vaccine Response | 000 | 1 | NIH | 3/27/2025 | $95,392 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01EY034565 | Optimizing methotrexate use for the management of chronic pediatric non-infectious uveitis | 000 | 3 | NIH | 3/26/2025 | $560,861 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DK135478 | Organoid-guided Precision Hepatology for Steatohepatitis | 000 | 2 | NIH | 2/19/2025 | $530,803 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AI184466 | Naive CD8 T cell functional heterogeneity | 000 | 1 | NIH | 3/19/2025 | $639,084 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL166335 | Early detection of pulmonary complications of hematopoietic stem-cell transplantation in children using hyperpolarized xenon MRI | 000 | 3 | NIH | 1/8/2025 | $634,864 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01CA253981 | Modeling myelodysplasia | 000 | 5 | NIH | 1/8/2025 | $520,466 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL160569 | Microprotein Regulation of Mitochondrial Function | 000 | 4 | NIH | 11/13/2024 | $397,500 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R00HD104902 | Genomic and functional analyses of Polycomb group proteins in mouse preimplantation development | 000 | 5 | NIH | 1/8/2025 | $214,379 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS121042 | Anti-epileptogenic role of mTOR activation among hippocampal interneurons | 000 | 4 | NIH | 11/14/2024 | $443,523 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL172914 | Cellular determinants of responsiveness to mTOR inhibitors in LAM | 000 | 1 | NIH | 1/30/2025 | $739,236 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | K08CA237753 | Targeting MBNL1-mediated alternative splicing in MLL-fusion leukemia | 000 | 5 | NIH | 2/13/2025 | $196,112 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DK095001 | Genetic and microenvironmental regulation of macrophage functions driving biliary fibrosis in pediatric PSC | 000 | 10 | NIH | 3/13/2025 | $533,386 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL156852 | Innate immune response signaling in cardiac injury healing | 000 | 4 | NIH | 11/29/2024 | $544,642 |
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