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 | Issue Date FY: 2025 ( Subtotal = $60,111,832 ) (Continued on the next page) |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01CA278834 | The role of DNAJB1-PKAc-β-catenin axis in fibrolamellar HCC | 000 | 3 | NIH | 3/4/2025 | $573,569 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01CA271455 | Dissecting innate immune signaling in pre-leukemia evolution | 000 | 4 | NIH | 3/5/2025 | $574,418 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DK133198 | Cutaneous biomarkers of pediatric non-alcoholic fatty liver disease | 000 | 4 | NIH | 4/17/2025 | $639,629 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | U01AI152034 | Atopic dermatitis: mechanisms of disease progression | 000 | 6 | NIH | 3/24/2025 | $224,999 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AG078174 | Coordinated mechanisms to rescue bioenergetics and sarcopenia in aging | 000 | 4 | NIH | 4/16/2025 | $293,355 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | UH3NS129558 | A Phase 3 clinical trial of an e-health behavioral intervention to improve executive functioning in adolescents with epilepsy | 000 | 2 | NIH | 4/22/2025 | $1,907,458 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AR079524 | Pathogenesis of Systemic Juvenile Idiopathic Arthritis-Associated Lung Disease | 000 | 4 | NIH | 4/30/2025 | $525,487 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F32HD118646 | Role of Gsx2 in hindbrain neurogenesis | 000 | 1 | NIH | 4/25/2025 | $73,828 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F32HD118646 | Role of Gsx2 in hindbrain neurogenesis | 001 | 1 | NIH | 4/25/2025 | $0 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | U01DK134976 | Cincinnati Children's Clinical Center for Targeting the Pathophysiology of Youth-Onset Type 2 Diabetes | 000 | 3 | NIH | 2/14/2025 | $751,761 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01FD007267 | Abatacept for the treatment of Common Variable Immunodeficiency with Interstitial Lung Disease (ABCVILD) IND #152820 9/2/20 | 002 | 3 | FDA | 3/21/2025 | $0 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01FD007267 | Abatacept for the treatment of Common Variable Immunodeficiency with Interstitial Lung Disease (ABCVILD) IND #152820 9/2/20 | 001 | 3 | FDA | 3/5/2025 | $0 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01FD007267 | Abatacept for the treatment of Common Variable Immunodeficiency with Interstitial Lung Disease (ABCVILD) IND #152820 9/2/20 | 000 | 3 | FDA | 1/16/2025 | $529,803 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HD110321 | Screen Smart: Using Digital Health to Improve HIV Screening and Prevention for Adolescents in the Emergency Department | 000 | 3 | NIH | 4/24/2025 | $778,394 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | K08GM148957 | Mechanisms of cardiomyocyte dysfunction in pediatric septic shock | 000 | 3 | NIH | 1/24/2025 | $192,024 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F30AI157421 | Silencer Control of T cell Homeostasis | 000 | 4 | NIH | 10/31/2024 | $53,974 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21AI178517 | Role of Innate Lymphocytes in Obese Asthma | 000 | 2 | NIH | 10/31/2024 | $194,606 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01MH122415 | Longitudinal Examination of Sluggish Cognitive Tempo and Internalizing Psychopathology in Adolescence | 000 | 5 | NIH | 12/5/2024 | $636,720 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS125316 | Understanding the Impact of Youth Onset Obesity and Type 2 Diabetes on the Neurovascular Unit | 000 | 4 | NIH | 1/27/2025 | $333,869 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS125316 | Understanding the Impact of Youth Onset Obesity and Type 2 Diabetes on the Neurovascular Unit | 000 | 4 | NIH | 1/27/2025 | $80,587 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL158100 | Effect of reproductive history on longitudinal change in cardiac, vascular and lipid parameters | 000 | 4 | NIH | 12/3/2024 | $617,753 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | U01AI159087 | Multi-omics of the Frequent Exacerbator Asthmatic | 000 | 5 | NIH | 4/14/2025 | $452,000 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DK133145 | Diabetic Memory in Hematopoietic Stem Cells | 000 | 3 | NIH | 1/1/2025 | $399,184 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R35GM155165 | Translational approaches to unravel organ-specific microvascular endothelial responses in sepsis. | 000 | 2 | NIH | 4/17/2025 | $401,250 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F30AI181481 | Mechanisms of Longitudinal Microbial Colonization in Pediatric Atopic Dermatitis | 000 | 2 | NIH | 12/13/2024 | $42,094 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL166245 | Defining PRC2 complex epigenomic control in alveolar progenitor cells | 000 | 3 | NIH | 11/18/2024 | $523,395 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HD113529 | A Multisite RCT of a Daily Living Skills Intervention for Autistic Adolescents Prior to the Transition to Adulthood | 000 | 2 | NIH | 4/2/2025 | $661,679 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS121042 | Anti-epileptogenic role of mTOR activation among hippocampal interneurons | 000 | 4 | NIH | 11/14/2024 | $443,523 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R33HL166441 | Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent Rheumatic Heart Disease: A non-inferiority randomized trial. (GOALIE) | 000 | 3 | NIH | 12/13/2024 | $1,566,104 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL156866 | Pathogenesis and Treatment of Kaposiform Lymphangiomatosis | 000 | 4 | NIH | 1/6/2025 | $556,510 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL156852 | Innate immune response signaling in cardiac injury healing | 000 | 4 | NIH | 11/29/2024 | $544,642 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL105924 | Thrombospondin 4 regulates adaptive ER stress responseRenewal - Resubmission - 1 | 000 | 14 | NIH | 12/6/2024 | $539,027 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F31HL172346 | Effects of early Retinoic Acid signaling on valve development | 000 | 2 | NIH | 1/20/2025 | $41,915 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AI186611 | Viral and Cellular Determinants of HIV-1 Assembly | 000 | 2 | NIH | 4/14/2025 | $609,012 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DK135497 | A Novel Obesity Prevention Program for High-Risk Infants in Primary Care | 000 | 3 | NIH | 4/18/2025 | $318,000 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL168790 | Mechanisms governing the differentiation and maintenance of atrial identity | 000 | 3 | NIH | 4/10/2025 | $573,472 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AI184537 | Parity, paternity and pregnancy outcomes | 000 | 2 | NIH | 4/28/2025 | $631,863 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01CA278756 | Rational targeting of Cdc42 to benefit immunotherapy | 000 | 2 | NIH | 11/27/2024 | $534,962 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | K01DK135647 | Microbial regulation of intestinal tuft cell homeostasis | 000 | 3 | NIH | 12/10/2024 | $140,271 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R03AI185587 | Simplifying the transformation of laboratory test data for integration into the ImmPort database | 000 | 2 | NIH | 4/21/2025 | $80,250 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS028840 | Mitogenic Activities in Neurofibromatosis | 000 | 33 | NIH | 2/14/2025 | $546,646 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R00HD104902 | Genomic and functional analyses of Polycomb group proteins in mouse preimplantation development | 001 | 5 | NIH | 4/24/2025 | $23,821 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R00HD104902 | Genomic and functional analyses of Polycomb group proteins in mouse preimplantation development | 000 | 5 | NIH | 1/8/2025 | $214,379 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DE033890 | Molecular Regulation of Palate Development | 001 | 2 | NIH | 5/5/2025 | $66,417 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DE033890 | Molecular Regulation of Palate Development | 000 | 2 | NIH | 12/3/2024 | $597,758 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AI176519 | Blocking granzyme-mediated immune suppression to enhance HIV vaccine efficacy | 000 | 3 | NIH | 4/21/2025 | $556,715 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | K23MH125138 | A Family Navigator Intervention to Improve ADHD- Related Treatment Adherence (I2-ART) for Minority Children | 000 | 5 | NIH | 12/9/2024 | $187,176 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F31HL167596 | Mucosal Associated Invariant T cells in the Obese-asthma endotype | 000 | 3 | NIH | 12/13/2024 | $41,915 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01ES031621 | Longitudinal Impact of Air Pollution on Mental Health and Neuroimaging Outcomes during Adolescence in the Cincinnati Combined Childhood Cohorts (C4) | 000 | 5 | NIH | 1/6/2025 | $932,831 |
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