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 | Issue Date FY: 2025 ( Subtotal = $89,805,776 ) (Continued on the next page) |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R35GM155165 | Translational approaches to unravel organ-specific microvascular endothelial responses in sepsis. | 000 | 2 | NIH | 4/17/2025 | $401,250 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DE032558 | Genomic and Developmental Mechanisms of SIX2-Related Frontonasal Dysplasia | 000 | 2 | NIH | 6/3/2025 | $622,607 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS125316 | Understanding the Impact of Youth Onset Obesity and Type 2 Diabetes on the Neurovascular Unit | 000 | 4 | NIH | 1/27/2025 | $80,587 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS125316 | Understanding the Impact of Youth Onset Obesity and Type 2 Diabetes on the Neurovascular Unit | 000 | 4 | NIH | 1/27/2025 | $333,869 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DK137771 | Epigenetic regulation of intestinal tuft cells | 000 | 2 | NIH | 6/18/2025 | $627,541 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | U01AI159087 | Multi-omics of the Frequent Exacerbator Asthmatic | 000 | 5 | NIH | 4/14/2025 | $452,000 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL169242 | Allogeneic virus-specific T-cell therapy after hematopoietic stem cell transplant: determinants of treatment success and failure | 000 | 2 | NIH | 5/7/2025 | $646,249 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL158100 | Effect of reproductive history on longitudinal change in cardiac, vascular and lipid parameters | 000 | 4 | NIH | 12/3/2024 | $617,753 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | K08GM148957 | Mechanisms of cardiomyocyte dysfunction in pediatric septic shock | 000 | 3 | NIH | 1/24/2025 | $192,024 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F30AI157421 | Silencer Control of T cell Homeostasis | 000 | 4 | NIH | 10/31/2024 | $53,974 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R33HL166441 | Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent Rheumatic Heart Disease: A non-inferiority randomized trial. (GOALIE) | 000 | 3 | NIH | 12/13/2024 | $1,566,104 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R21AI178517 | Role of Innate Lymphocytes in Obese Asthma | 000 | 2 | NIH | 10/31/2024 | $194,606 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01MH122415 | Longitudinal Examination of Sluggish Cognitive Tempo and Internalizing Psychopathology in Adolescence | 000 | 5 | NIH | 12/5/2024 | $636,720 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS121042 | Anti-epileptogenic role of mTOR activation among hippocampal interneurons | 000 | 4 | NIH | 11/14/2024 | $443,523 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HD113529 | A Multisite RCT of a Daily Living Skills Intervention for Autistic Adolescents Prior to the Transition to Adulthood | 000 | 2 | NIH | 4/2/2025 | $661,679 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AR084717 | Natural history and validation of surrogate biomarkers and patient-reported outcomes for SJIA-LD | 000 | 2 | NIH | 6/26/2025 | $170,878 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL156852 | Innate immune response signaling in cardiac injury healing | 000 | 4 | NIH | 11/29/2024 | $544,642 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL105924 | Thrombospondin 4 regulates adaptive ER stress responseRenewal - Resubmission - 1 | 000 | 14 | NIH | 12/6/2024 | $539,027 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | F31HL172346 | Effects of early Retinoic Acid signaling on valve development | 000 | 2 | NIH | 1/20/2025 | $41,915 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL156866 | Pathogenesis and Treatment of Kaposiform Lymphangiomatosis | 000 | 4 | NIH | 1/6/2025 | $556,510 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AI186611 | Viral and Cellular Determinants of HIV-1 Assembly | 000 | 2 | NIH | 4/14/2025 | $609,012 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DK135497 | A Novel Obesity Prevention Program for High-Risk Infants in Primary Care | 000 | 3 | NIH | 4/18/2025 | $318,000 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AI173314 | Gene regulatory network modeling of disease-associated DNA methylation perturbations | 000 | 3 | NIH | 6/5/2025 | $762,041 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL168790 | Mechanisms governing the differentiation and maintenance of atrial identity | 000 | 3 | NIH | 4/10/2025 | $573,472 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL166245 | Defining PRC2 complex epigenomic control in alveolar progenitor cells | 000 | 3 | NIH | 11/18/2024 | $523,395 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS126108 | Midbrain pathways for visual hypersensitivity in neurofibromatosis type 1 | 000 | 3 | NIH | 6/27/2025 | $384,128 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01CA278756 | Rational targeting of Cdc42 to benefit immunotherapy | 001 | 2 | NIH | 6/2/2025 | $59,440 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01CA278756 | Rational targeting of Cdc42 to benefit immunotherapy | 000 | 2 | NIH | 11/27/2024 | $534,962 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AI184537 | Parity, paternity and pregnancy outcomes | 000 | 2 | NIH | 4/28/2025 | $631,863 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | K01DK135647 | Microbial regulation of intestinal tuft cell homeostasis | 000 | 3 | NIH | 12/10/2024 | $140,271 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R03AI185587 | Simplifying the transformation of laboratory test data for integration into the ImmPort database | 000 | 2 | NIH | 4/21/2025 | $80,250 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS028840 | Mitogenic Activities in Neurofibromatosis | 000 | 33 | NIH | 2/14/2025 | $546,646 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DE033890 | Molecular Regulation of Palate Development | 001 | 2 | NIH | 5/5/2025 | $66,417 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DE033890 | Molecular Regulation of Palate Development | 000 | 2 | NIH | 12/3/2024 | $597,758 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DK136512 | The role of serpins and LRP1 in the esophageal epithelium during eosinophilic esophagitis | 000 | 2 | NIH | 6/13/2025 | $553,337 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | K23DK135797 | Disrupted sleep architecture in adolescents with functional abdominal pain disorders | 000 | 3 | NIH | 1/17/2025 | $191,007 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R00HD104902 | Genomic and functional analyses of Polycomb group proteins in mouse preimplantation development | 001 | 5 | NIH | 4/24/2025 | $23,821 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R00HD104902 | Genomic and functional analyses of Polycomb group proteins in mouse preimplantation development | 000 | 5 | NIH | 1/8/2025 | $214,379 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DK134646 | RNA silencing machinery in extracellular vesicle-mediated immunometabolic regulation | 001 | 2 | NIH | 6/12/2025 | $58,877 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DK134646 | RNA silencing machinery in extracellular vesicle-mediated immunometabolic regulation | 000 | 2 | NIH | 11/25/2024 | $529,898 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01NS124660 | Roles of Gsx factors in basal ganglia development | 000 | 4 | NIH | 1/3/2025 | $550,588 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01ES031621 | Longitudinal Impact of Air Pollution on Mental Health and Neuroimaging Outcomes during Adolescence in the Cincinnati Combined Childhood Cohorts (C4) | 000 | 5 | NIH | 1/6/2025 | $932,831 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HD094862 | Dosing and Pilot Efficacy of 2'-Fucosyllactose in Inflammatory Bowel Disease | 002 | 7 | NIH | 6/26/2025 | $677,278 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HD068524 | Molecular signaling in uterine receptivity to implantation | 000 | 13 | NIH | 3/11/2025 | $395,158 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HD068524 | Molecular signaling in uterine receptivity to implantation | 001 | 13 | NIH | 4/24/2025 | $43,906 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01AI153442 | An experimentally-refined, dynamic gene regulatory network model of T-cell memory | 000 | 5 | NIH | 2/13/2025 | $633,135 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | K08CA237753 | Targeting MBNL1-mediated alternative splicing in MLL-fusion leukemia | 000 | 5 | NIH | 2/13/2025 | $196,112 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01DK140321 | The Roles of MRP9 in cholangiocyte metabolism | 000 | 1 | NIH | 7/1/2025 | $806,192 |
| | 2025 | 2025 | CHILDRENS HOSPITAL MEDICAL CENTER | 3333 BURNET AVE | CINCINNATI | OH | 45229-3039 | HAMILTON | USA | R01HL131012 | Regional monitoring of CF lung disease after changes in mechanical airway-clearance treatment | 001 | 8 | NIH | 4/7/2025 | $720,465 |
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