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Neurosphysiological and behavioral studies of expectancy bias in trauma survivors

Award Number: R15MH081276
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/01/2008
PERIOD OF PERFORMANCE END DATE: 05/31/2020

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Neurosphysiological and behavioral studies of expectancy bias in trauma survivors - ¿ DESCRIPTION (provided by applicant): The impact of psychological trauma on the population is significant. Research suggests that as many as 60.7% of men and 51.2% of women in America have been exposed to at least one extreme stressor or traumatizing event during the course of their lives. For those who develop chronic reactions to the traumatic events, the impact is considerable. Among the concerns are cognitive biases towards generalized and persistent negative appraisals. The scope of this problem is quite broad and likely includes negative evaluations of themselves, of others, and of the world. In the past, this has been captured in the diagnostic criteria of "hypervigilance" and a "sense of foresohrtened future." These symptoms both reflect an appreciation for the ongoing sense of threat that many carry with them after trauma. More recently, the proposed criteria for the DSM-V have included a new symptom, namely "persistent and exaggerated negative expectations about one's self, others, or the world" in recognition of the central role negative appraisals and expectations play in the lives of some trauma survivors. In this proposal with intend to use event-related potentials (ERPs) and eye tracking technology to investigate the neurophysiological and behavioral correlates of expectancy biases and avoidance in traumatized individuals. Study Design: The project will involve the participation of 90 individuals who vary in their trauma history and PTSD status. All participants will undergo a thorough diagnostic evaluation to assess the extent of trauma and current psychopathology. The diagnostic evaluation will be followed by an assessment which will take a multi-method approach to evaluating expectancy bias including self report measures, event-related potentials (e.g., brain waves), and eye tracking technology. Objective: The overall goal of this project is the better understand how trauma and PTSD impact on expectancy in the trauma survivor. This project will achieve this goal by answering questions such as 1) Does trauma alone affect expectancies or is PTSD necessary? 2) Are expectancy biases reflected in underlying brain activity? 3) Do expectancy biases predict behaviors such as hypervigilance? 4) Do individuals engage visual and cognitive vigilance in order to initiate behavioral avoidance? This proposal reflects an important continuation and extension of previous work by this group on attentional bias after trauma.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2022 ( Subtotal = -$33,203 )
2022	2015	PRESIDENT AND FELLOWS OF MIDDLEBURY COLLEGE	9 OLD CHAPEL RD	MIDDLEBURY	VT	05753	ADDISON	USA	Mental Health Research Grants	000	3	10/1/2021	COMPETING CONTINUATION	-$33,203
														Subtotal = -$33,203

Issue Date FY: 2019 ( Subtotal = $0 )
2019	2015	PRESIDENT AND FELLOWS OF MIDDLEBURY COLLEGE	38 COLLEGE ST	MIDDLEBURY	VT	05753	ADDISON	USA	Mental Health Research Grants	000	3	6/25/2019	COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2018 ( Subtotal = $0 )
2018	2015	PRESIDENT AND FELLOWS OF MIDDLEBURY COLLEGE	38 COLLEGE ST	MIDDLEBURY	VT	05753	ADDISON	USA	Mental Health Research Grants	000	3	3/30/2018	COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2015 ( Subtotal = $313,262 )
2015	2015	MIDDLEBURY COLLEGE	OLD CHAPEL BUILDING	MIDDLEBURY	VT	05753	ADDISON	USA	Mental Health Research Grants	002	3	5/7/2015	COMPETING CONTINUATION	$313,262
2015	2015	MIDDLEBURY COLLEGE	OLD CHAPEL BUILDING	MIDDLEBURY	VT	05753	ADDISON	USA	Mental Health Research Grants	003	3	5/8/2015	COMPETING CONTINUATION	$0
2015	2012	MIDDLEBURY COLLEGE	OLD CHAPEL BUILDING	MIDDLEBURY	VT	05753	ADDISON	USA	Mental Health Research Grants	000	2	10/27/2014	COMPETING CONTINUATION	$0
2015	2012	MIDDLEBURY COLLEGE	OLD CHAPEL BUILDING	MIDDLEBURY	VT	05753	ADDISON	USA	Mental Health Research Grants	001	2	5/1/2015	COMPETING CONTINUATION	$0
														Subtotal = $313,262

Issue Date FY: 2012 ( Subtotal = $287,944 )
2012	2012	MIDDLEBURY COLLEGE	OLD CHAPEL BUILDING	MIDDLEBURY	VT	05753	ADDISON	USA	Mental Health Research Grants	001	2	12/1/2011	COMPETING CONTINUATION	$287,944
2012	2012	MIDDLEBURY COLLEGE	OLD CHAPEL BUILDING	MIDDLEBURY	VT	05753	ADDISON	USA	Mental Health Research Grants	002	2	12/23/2011	COMPETING CONTINUATION	$0
2012	2008	MIDDLEBURY COLLEGE	OLD CHAPEL BUILDING	MIDDLEBURY	VT	05753	ADDISON	USA	Mental Health Research Grants	000	1	11/29/2011	NEW	$0
														Subtotal = $287,944

Issue Date FY: 2008 ( Subtotal = $186,830 )
2008	2008	MIDDLEBURY COLLEGE	OLD CHAPEL BUILDING	MIDDLEBURY	VT	05753	ADDISON	USA	Mental Health Research Grants	000	1	5/24/2008	NEW	$186,830
														Subtotal = $186,830

Grand Total All Awards = $754,833

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Neurosphysiological and behavioral studies of expectancy bias in trauma survivors

Award Number: R15MH081276

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/01/2008

PERIOD OF PERFORMANCE END DATE: 05/31/2020

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