Wednesday, May 21, 2025
5/21/2025
Neurosphysiological and behavioral studies of expectancy bias in trauma survivors - ¿ DESCRIPTION (provided by applicant): The impact of psychological trauma on the population is significant. Research suggests that as many as 60.7% of men and 51.2% of women in America have been exposed to at least one extreme stressor or traumatizing event during the course of their lives. For those who develop chronic reactions to the traumatic events, the impact is considerable. Among the concerns are cognitive biases towards generalized and persistent negative appraisals. The scope of this problem is quite broad and likely includes negative evaluations of themselves, of others, and of the world. In the past, this has been captured in the diagnostic criteria of "hypervigilance" and a "sense of foresohrtened future." These symptoms both reflect an appreciation for the ongoing sense of threat that many carry with them after trauma. More recently, the proposed criteria for the DSM-V have included a new symptom, namely "persistent and exaggerated negative expectations about one's self, others, or the world" in recognition of the central role negative appraisals and expectations play in the lives of some trauma survivors. In this proposal with intend to use event-related potentials (ERPs) and eye tracking technology to investigate the neurophysiological and behavioral correlates of expectancy biases and avoidance in traumatized individuals. Study Design: The project will involve the participation of 90 individuals who vary in their trauma history and PTSD status. All participants will undergo a thorough diagnostic evaluation to assess the extent of trauma and current psychopathology. The diagnostic evaluation will be followed by an assessment which will take a multi-method approach to evaluating expectancy bias including self report measures, event-related potentials (e.g., brain waves), and eye tracking technology. Objective: The overall goal of this project is the better understand how trauma and PTSD impact on expectancy in the trauma survivor. This project will achieve this goal by answering questions such as 1) Does trauma alone affect expectancies or is PTSD necessary? 2) Are expectancy biases reflected in underlying brain activity? 3) Do expectancy biases predict behaviors such as hypervigilance? 4) Do individuals engage visual and cognitive vigilance in order to initiate behavioral avoidance? This proposal reflects an important continuation and extension of previous work by this group on attentional bias after trauma.
HHS’ Tracking Accountability in Government Grants System (TAGGS) website provides access to detailed descriptions of grants, loans, aggregated direct payments and other types of financial assistance awarded by the HHS Operating Divisions (OPDIVs) and the Office of the Secretary Staff Divisions (STAFFDIVs).