Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( 🔒 ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Need Help

Molecular control of translesion synthesis fidelity beyond the lesion

Award Number: R15GM155805
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/02/2024
PERIOD OF PERFORMANCE END DATE: 06/30/2027

Group Awards By:

View Award Description

Molecular control of translesion synthesis fidelity beyond the lesion - Project Summary: This proposed administrative supplement is for the purchase of a new refrigerated high speed floor centrifuge to support research related to the parent grant as well as other NIH-funded research in the PI's department. This instrument will replace an older, outdated, and unsupported Beckman Avanti J-26XP instrument that is in decline with identified serious safety and mechanical concerns. Replacement of this instrument with a newer Beckman Avanti J-26S XP will ensure the efficient completion of the aims outlined in the original proposal (R15GM155805). High speed centrifugation is a fundamental but critical component of biomedical research ensuring the efficient purification of recombinant proteins from several expression sources, the isolation of bacmids and plasmids as well as the purification of DNA substrates for the proposed experiments, and the ability to separate various protein/DNA complexes through sucrose gradients. Without this ability, it will be more difficult to purify the requisite proteins/enzymes with lower overall purities, to isolate various plasmids, bacmids, and DNA substrates utilized, and to easily and quickly detect protein/DNA complexes and mutational disruptions. For these reasons, we request supplemental funds to update our centrifugation needs and capacities to ensure the effective research and training of undergraduate and graduate students supported by this research.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $60,818 )
2026	2026	BAYLOR UNIVERSITY	700 S UNIVERSITY PARKS DR	WACO	TX	76706	MCLENNAN	USA	Biomedical Research and Research Training	000	1	6/23/2026	SUPPLEMENT FOR EXPANSION	$60,818
														Subtotal = $60,818

Issue Date FY: 2024 ( Subtotal = $420,000 )
2024	2024	BAYLOR UNIVERSITY	700 S UNIVERSITY PARKS DR	WACO	TX	76706	MCLENNAN	USA	Biomedical Research and Research Training	000	1	7/2/2024	NEW	$420,000
														Subtotal = $420,000

Grand Total All Awards = $480,818

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Molecular control of translesion synthesis fidelity beyond the lesion

Award Number: R15GM155805

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/02/2024

PERIOD OF PERFORMANCE END DATE: 06/30/2027

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer