Friday, June 27, 2025 6/27/2025

Preparative binary pump HPLC system with UV and refractive index detector capabilities

Award Number: R15GM152969
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/18/2023
PERIOD OF PERFORMANCE END DATE: 08/31/2026

Group Awards By:

View Award Description

Preparative binary pump HPLC system with UV and refractive index detector capabilities - Our NIH-funded project (1 R15GM152969-01) focuses on synthesizing and characterizing fluorescent probes operating in the red to near-infrared region to measure pH levels within organelles. The current synthesis involves multiple steps, with silica gel chromatography causing delays and inefficiencies. The proposal suggests acquiring a preparative high-pressure liquid chromatography (HPLC) system to improve purification at each step, addressing the limitations of traditional silica gel column chromatography. The decision is driven by the complexity of the probes and the need for enhanced resolution in separating closely related compounds. The shift to preparative HPLC is expected to streamline the synthesis process and improve the overall efficiency of the project.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $77,283 )
2024	2024	MICHIGAN TECHNOLOGICAL UNIVERSITY	1400 TOWNSEND DR	HOUGHTON	MI	49931	HOUGHTON	USA	Biomedical Research and Research Training	000	1	5/21/2024	SUPPLEMENT FOR EXPANSION	$77,283
														Subtotal = $77,283

Issue Date FY: 2023 ( Subtotal = $469,500 )
2023	2023	MICHIGAN TECHNOLOGICAL UNIVERSITY	1400 TOWNSEND DR	HOUGHTON	MI	49931	HOUGHTON	USA	Biomedical Research and Research Training	000	1	9/15/2023	NEW	$469,500
														Subtotal = $469,500

Grand Total All Awards = $546,783

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Preparative binary pump HPLC system with UV and refractive index detector capabilities

Award Number: R15GM152969

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/18/2023

PERIOD OF PERFORMANCE END DATE: 08/31/2026

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer