2026 Cell Biology of the Neuron Gordon Research Conference and Seminar - Abstract This application requests partial support for early career investigators, postdoctoral fellows, and graduate students to attend the 2026 Gordon Research Conference (GRC) and the accompanying Gordon Research Seminar (GRS) on the Cell Biology of the Neuron, to be held in the Renaissance Tuscany Il Ciocco, Italy, during the week of June 6–12, 2026. The Cell Biology of the Neuron GRC serves as the primary venue for presenting and discussing unpublished, cutting-edge discoveries in the international community of researchers in neuronal cell biology. The 2026 conference will highlight emerging themes and innovative technologies at the interface of cell biology and neuroscience, focusing on fundamental mechanisms underlying neuronal function, communication, and dysfunction. The in-depth knowledge of the complex cell biology within individual neurons is essential for understanding the neuronal communication that underlies virtually all aspects of behavior, sensation, and cognition. Molecular and cellular understanding of neuronal function is also critical to tackling questions of neuronal dysfunction in neurodevelopmental and neurodegenerative disorders. Progress in this field increasingly requires interdisciplinary efforts that integrate cell biology, molecular biology, genetics, advanced imaging, computational modeling, and systems neuroscience. The Cell Biology of the Neuron GRC and GRS provide a unique venue to bring together neuroscientists interested in synaptic architecture and connectivity, cytoskeletal dynamics, organelle and RNA trafficking, neuronal polarity and regeneration, as well as those applying artificial intelligence (AI) and computational approaches to neuronal cell biology. Through invited and abstract-selected talks as well as poster sessions, the meeting will unite scientists employing different methodologies to tackle fundamental unresolved questions regarding neuronal cell function - questions crucial for elucidating neuronal pathologies at a mechanistic level and for providing new insights for their treatment. The multidisciplinary theme and shared focus will facilitate communication across the entire continuum of molecular and cellular neuronal biology. The specific aims of the 2026 GRC meeting will be to convene 32 invited speakers and 9 discussion leaders for a total of 200 participants for a five-day conference, which will; (1) advance emerging themes in neuronal function, homeostasis, and disease, and (2) support the next generation of neuroscientists by fostering cross-disciplinary interactions and by providing training and mentorship opportunities for early-career researchers. We anticipate a highly interactive meeting characterized by dynamic discussions among speakers, discussion leaders, and participants. The conference will catalyze new collaborations and research directions, continuing this GRC’s tradition of excellence and its vital role in shaping the future of neuronal cell biology.