2024 Optogenetic Approaches to Understanding Neural Circuits and Behavior Gordon Research Conference and Seminar - Project Summary The next Gordon Research Conference (GRC) on Optogenetic Approaches to Understanding Neural Circuits and Behavior will convene in Lucca (Barga), Italy, on July 21-26, 2024. This will be the fourth time that this international conference brings together the diverse community of scientists using optogenetics to interrogate brain function with the overall goal of fostering an inclusive and collaborative environment for scientific exchange. The optogenetics community is comprised of tool developers and users, experimentalists and theorists, bioengineers, clinicians, and basic scientists. The optogenetics toolbox has rapidly expanded and allows researchers to alter activity in genetically defined cell types and pathways, to mimic neurotransmitters and neuromodulators and monitor the activity of intracellular processes. While such rapid progress in the field has brought a wealth of tools and techniques into the hands of researchers, the field faces the challenge of defining best practices and rigorous standards to ensure proper experimental study design and data interpretation. These issues are of paramount importance as the field witnesses a transition from bench to bedside with the translation of optogenetic tools to treat human disease. The Optogenetics GRC places as much value on encouraging speakers to discuss details regarding techniques and implementation as it does on highlighting exciting study outcomes. The major aims of the conference are to (1) expose participants to emerging optogenetic tools, gene targeting approaches, and optical innovations, (2) highlight innovative applications and translation of optogenetic approaches, (3) feature recent research innovations from junior scientists, (4) support networking opportunities to enhance trainee learning, mentorship, inclusion, and professional development. To meet these goals, the conference will feature a diverse platform of scientific sessions that include keynote speakers and established investigators as well as junior investigators in the earliest stages of their careers. Beyond the scientific sessions, the meeting will include dedicated mentoring activities for junior investigators and a GRC Power Hour to discuss issues facing women and underrepresented groups. The GRC will be preceded by a Gordon Research Seminar (GRS), which provides a unique opportunity for junior investigators to engage in scientific discussion before attending the GRC.
