Monday, June 23, 2025 6/23/2025

The Protein Aggregation Conference: Exploring Rugged Landscapes

Award Number: R13NS132547
ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 06/01/2023
PERIOD OF PERFORMANCE END DATE: 05/31/2024

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The Protein Aggregation Conference: Exploring Rugged Landscapes - Project Summary Protein aggregation is critical to both normal and pathological biological phenomena. Inappropriate protein aggregation underpins many neurological and systemic diseases, especially those associated with aging. Despite enormous progress in the advancement of knowledge for how protein aggregation relates to disease pathogenesis there remain few effective therapies for these diseases - especially relative to the successes in cardiovascular diseases and cancer. Recent discoveries have unearthed numerous examples of functional protein aggregation in membraneless organelles and signaling pathways. The structural bases of such phenomena include not only amyloids and other ordered polymers but also liquid-liquid phase separation. The mechanisms and regulation of these forms of aggregation are still being deciphered, but are already illuminating fruitful intersections with pathological aggregation. These new directions in the field place protein aggregation at an energetic and exciting moment of progress. This R13 proposal seeks support for a FASEB Summer Research Conference on “Protein Aggregation: Exploring Rugged Landscapes”. This will be the fourteenth conference of a series that began in 1995. Our 4-day program will bring the best researchers on the most cutting- edge topics of the discipline, while emphasizing diversity, equity, and inclusion. We will use the R13 funding to support these measures and further increase engagement by junior researchers.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2023	FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL BIOLOGY	6120 EXECUTIVE BLVD STE 575	ROCKVILLE	MD	20852	MONTGOMERY	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	1	10/16/2024	NEW	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $15,000 )
2023	2023	FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL BIOLOGY	6120 EXECUTIVE BLVD STE 600	ROCKVILLE	MD	20852	MONTGOMERY	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	1	3/29/2023	NEW	$15,000
														Subtotal = $15,000

Grand Total All Awards = $15,000

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The Protein Aggregation Conference: Exploring Rugged Landscapes

Award Number: R13NS132547

ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 06/01/2023

PERIOD OF PERFORMANCE END DATE: 05/31/2024

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