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T Cells in the Brain (TCB2027): Decoding T Cell Targets in Neurodegeneration

Award Number: R13AG104346
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/05/2026
PERIOD OF PERFORMANCE END DATE: 08/31/2027

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T Cells in the Brain (TCB2027): Decoding T Cell Targets in Neurodegeneration - ABSTRACT T cells are key contributors to neuroinflammation and neurodegeneration, yet identifying their targets and antigen specificities in human neurological disease remains a major challenge. Rapid advances in neuroimmunology, including single-cell multiomics, TCR repertoire sequencing, and antigen-discovery platforms, have begun to reshape our understanding of T cell biology in the CNS. Building on the success of TCB2024 and TCB2025, which each convened over 200 national and international attendees, the T Cells in the Brain series has established itself as the premier forum for integrating T cell biology with human neurodegeneration. These meetings generated new multi-institutional collaborations, fostered technology exchange among immunologists, neuropathologists, T cell engineers, and computational biologists, and supported several emerging joint grant applications and shared datasets. “T Cells in the Brain (TCB2027): Decoding T Cell Targets in Neurodegeneration” will advance this momentum by consolidating recent progress and promoting interdisciplinary discussion toward precision T-cell-based therapies. TCB remains committed to active efforts to engage trainees, and junior researchers. By uniting interdisciplinary expertise and strengthening collaborative networks, TCB2027 aims to accelerate the development of effective T cell-based interventions for neurodegenerative disorders.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $50,000 )
2026	2026	MAYO CLINIC ARIZONA	13400 E SHEA BLVD	SCOTTSDALE	AZ	85259	MARICOPA	USA	Aging Research	000	1	9/2/2026	NEW	$50,000
														Subtotal = $50,000

Grand Total All Awards = $50,000

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T Cells in the Brain (TCB2027): Decoding T Cell Targets in Neurodegeneration

Award Number: R13AG104346

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/05/2026

PERIOD OF PERFORMANCE END DATE: 08/31/2027

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