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 | Issue Date FY: 2025 ( Subtotal = -$764,519 ) |
| | 2025 | 2025 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01HL133501 | Activation of the Secretin Receptor as a Strategy for the Treatment of Heart Failure | 000 | 7 | NIH | 11/11/2024 | $409,169 |
| | 2025 | 2025 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01HL162747 | Strategies to Enhance Engineered Heart Tissue Based Myocardial Repair | 000 | 3 | NIH | 11/9/2024 | $652,089 |
| | 2025 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R33NS113315 | Biomarker Signature to Predict the Persistence of Post-Traumatic Headache | 000 | 3 | NIH | 10/1/2024 | -$675,765 |
| | 2025 | 2023 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01CA234181 | Credentialing a Genetically Engineered Clinically-Relevant Mouse Model of Multiple Myeloma | 000 | 5 | NIH | 10/29/2024 | $0 |
| | 2025 | 2022 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | P01CA229100 | Molecular Diagnosis, Prognosis, and Therapeutic Targets in Lymphoma | 000 | 5 | NIH | 11/5/2024 | $0 |
| | 2025 | 2022 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01HL142627 | Myocardial Repair with a Novel Engineered Cardiac Muscle Patch | 000 | 4 | NIH | 10/9/2024 | $0 |
| | 2025 | 2019 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | RF1AG062110 | Microglial apoE in neuroinflammation and Alzheimer's disease | 000 | 1 | NIH | 10/1/2024 | -$32,603 |
| | 2025 | 2019 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | RF1AG062077 | Novel genetic modifiers of C9orf72 and Tau toxicity | 000 | 2 | NIH | 10/1/2024 | -$356,504 |
| | 2025 | 2019 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01DK123138 | Validation of peripheral CGRP signaling as a target for the treatment of pain in chronic pancreatitis | 002 | 2 | NIH | 10/1/2024 | -$280,533 |
| | 2025 | 2019 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01DK123138 | Validation of peripheral CGRP signaling as a target for the treatment of pain in chronic pancreatitis | 001 | 2 | NIH | 10/1/2024 | -$480,373 |
|
| Issue Date FY: 2024 ( Subtotal = $28,558,505 ) (Continued on the next page) |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01AI147652 | Molecular functions of Tcf-1 in DP thymocytes | 000 | 6 | NIH | 10/26/2023 | $373,500 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01CA289249 | Multimodal AI Fusion Model for Early Detection for Pancreatic Cancer | 000 | 1 | NIH | 9/16/2024 | $599,757 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R37AI071106 | Mechanisms of Allergen-induced Type 2 Immunity | 000 | 18 | NIH | 4/15/2024 | $578,847 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01DK130566 | Healing enterocutaneous fistulas using bioengineered biomaterials | 001 | 3 | NIH | 5/9/2024 | $34,240 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01DK130566 | Healing enterocutaneous fistulas using bioengineered biomaterials | 000 | 3 | NIH | 11/9/2023 | $513,592 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R21AI182888 | Pulmonary Response to Ozone-exposed Ragweed Pollen Grains | 001 | 1 | NIH | 9/11/2024 | $25,391 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | U54CA274504 | Mathematical Oncology Systems Analysis Imaging Center (MOSAIC) | 003 | 2 | NIH | 8/28/2024 | $79,052 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01CA264048 | Epigenetic mechanisms of carcinogenesis by Parvimonas micra, an oral cavity commensal turned colon cancer pathogen | 001 | 4 | NIH | 7/30/2024 | $575,706 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R37CA276047 | Targeting PP4 to improve ovarian cancer response to immunotherapy | 000 | 2 | NIH | 7/29/2024 | $434,357 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R21AI182888 | Pulmonary Response to Ozone-exposed Ragweed Pollen Grains | 000 | 1 | NIH | 6/13/2024 | $228,529 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01AI108682 | How beta-catenin expands Foxp3+RORgammat+ Pro-inflammatoryT-regulatory cells - Renewal | 001 | 10 | NIH | 6/26/2024 | $649,418 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01HL165176 | Biomaterials for embolization and ablation of arterio-venous malformations | 000 | 3 | NIH | 6/27/2024 | $595,892 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R37CA252060 | Enhancing cognitive function in breast cancer survivors through community-based aerobic exercise training | 003 | 4 | NIH | 7/11/2024 | $515,850 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | K01CA230193 | Genetic Literacy and Patient-Caregiver Communication of Prognostic Genetic Technology for Localized Prostate Cancer | 001 | 5 | NIH | 8/13/2024 | $168,264 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | U54CA274504 | Mathematical Oncology Systems Analysis Imaging Center (MOSAIC) | 002 | 2 | NIH | 8/21/2024 | $1,951,992 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01CA272426 | preclinical optimization of BCMA directed T cell therapy | 001 | 2 | NIH | 8/23/2024 | $590,784 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | U54CA274504 | Mathematical Oncology Systems Analysis Imaging Center (MOSAIC) | 001 | 1 | NIH | 7/31/2024 | $44,937 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | U01DK073983 | Advancing Science for the Diagnosis and Treatment of Gastroparesis | 002 | 18 | NIH | 8/5/2024 | $278,929 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01AG080037 | Diversity Supplement: The role of lymph node structural organization in naive T cell decline with age | 001 | 2 | NIH | 7/26/2024 | $66,026 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01HL133501 | Activation of the Secretin Receptor as a Strategy for the Treatment of Heart Failure | 001 | 6 | NIH | 6/24/2024 | $51,580 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01NS127922 | Novel Roles of TAZ and YAP in DNA Damage Repair with 3D Genome Organization and the Therapeutic Resistance in Glioblastoma | 001 | 2 | NIH | 7/26/2024 | $427,263 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | U01CA269264 | Flexible NLP toolkit for automatic curation of outcomes for breast cancer patients | 001 | 3 | NIH | 8/2/2024 | $507,016 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | UH3CA238926 | HRD-IA signatures in pancreatic ductal adenocarcinoma | 002 | 4 | NIH | 7/24/2024 | $0 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R35GM155031 | Engineering cell-based therapy for enhanced survival and durable function in vivo | 000 | 1 | NIH | 7/23/2024 | $416,250 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | K23AI158813 | Mechanisms of adverse gastrointestinal events during oral immunotherapy | 000 | 3 | NIH | 6/17/2024 | $189,864 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01AI170649 | Control of antiviral memory CD8+ T cell longevity by extracellular ATP sensing | 000 | 3 | NIH | 6/24/2024 | $473,714 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01HL156855 | Cardiomyocyte Non-autonomous Factors and Cardiac Regeneration in Large Mammals | 000 | 3 | NIH | 6/18/2024 | $654,653 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01CA271431 | STAT5/OLIG2 regulation of GBM therapeutic resistance and recurrence - Resubmit 3.22 | 001 | 2 | NIH | 4/18/2024 | $29,777 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01AA031257 | Biomarkers and pathogenesis of Alcoholic acute pancreatitis | 001 | 1 | NIH | 5/13/2024 | $0 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | UH3CA238926 | HRD-IA signatures in pancreatic ductal adenocarcinoma | 001 | 4 | NIH | 4/18/2024 | $17,221 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01AI128729 | Mechanisms of IL-33 secretion in allergic diseases | 001 | 8 | NIH | 5/24/2024 | $60,455 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01DK125680 | A randomized control trial of G-POEM for gastroparesis to assess feasibility, safety, efficacy and physiological mechanisms | 004 | 4 | NIH | 6/10/2024 | $518,756 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R21AI175813 | Delineating mechanisms underlying the enhanced stability and functionality of CD2- KO Tregs and chimeric antigen receptor (CAR) Tregs and their application in xenotransplantation | 001 | 3 | NIH | 5/17/2024 | $20,811 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01AG080037 | Diversity Supplement: The role of lymph node structural organization in naive T cell decline with age | 000 | 2 | NIH | 5/2/2024 | $591,539 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01CA271431 | STAT5/OLIG2 regulation of GBM therapeutic resistance and recurrence - Resubmit 3.22 | 000 | 2 | NIH | 1/29/2024 | $535,979 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R01AA031257 | Biomarkers and pathogenesis of Alcoholic acute pancreatitis | 000 | 1 | NIH | 2/29/2024 | $608,856 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | UH3CA238926 | HRD-IA signatures in pancreatic ductal adenocarcinoma | 000 | 4 | NIH | 1/30/2024 | $308,488 |
| | 2024 | 2024 | MAYO CLINIC ARIZONA | 13400 E SHEA BLVD | SCOTTSDALE | AZ | 85259-5452 | MARICOPA | USA | R13DC021115 | Society of Ears, Nose, and Throat Advances in Children (SENTAC) | 000 | 2 | NIH | 3/6/2024 | $40,000 |
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