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Developing a Young Adult-Mediated Intervention to Increase Colorectal Cancer Screening among Rural Screening Age-Eligible Adults

Award Number: R03CA270837
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 04/01/2023
PERIOD OF PERFORMANCE END DATE: 07/31/2026

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Developing a Young Adult-Mediated Intervention to Increase Colorectal Cancer Screening among Rural Screening Age-Eligible Adults - PROJECT SUMMARY Colorectal cancer (CRC) remains the second leading cause of cancer-related death in the United States. Recent studies have highlighted several geographic, primarily rural, “hotspots” for excess CRC incidence and mortality. One driver of these disparities between rural and non-rural populations is low CRC screening rates in rural areas. Thus, novel methods for improving screening and early detection in these areas are needed. The long-term objective of this research is to develop an intervention leveraging “upward communications” to improve CRC screening uptake in rural populations. The proposed R03 specific aims will help achieve this objective by garnering the preliminary information needed to develop a young adult-mediated intervention whereby a younger family member is taught to encourage their older family member to engage in CRC screening. Such an intervention could not only improve screening uptake among age-eligible adults, but could also improve cancer screening knowledge, awareness, and readiness among young adults themselves living in rural settings. The ORBIT model will guide the process of deliberatively developing and optimizing the intervention approach. Aims 1 and 2 will use mixed methods to collect formative data to identify critical intervention components. To complete Aim 1, survey data from n=150 younger (25-44 years old) and n=150 older (45-75 years old) adults living in rural communities will be collected. In Aim 2, we will develop and evaluate intervention components to facilitate effective upward communications about CRC prevention and screening using n=9 focus groups. We will iterate and modify intervention components based on focus group feedback. The results from Aims 1 and 2 will guide the refinement of intervention content and design. The impact of the novel intervention will be assessed via a single- arm, pre-test post-test trial design (n=15 adult child/parent dyads) in Aim 3. Tapping into and leveraging family members may be a particularly salient channel for culturally appropriate cancer communications in rural populations and may help address the unmet needs of CRC hotspot residents. Collectively, the proposed research will produce an upward communications intervention that has the potential to improve CRC health literacy and screening uptake in rural settings.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2025	VIRGINIA COMMONWEALTH UNIVERSITY	910 WEST FRANKLIN ST	RICHMOND	VA	23284	RICHMOND CITY	USA	Cancer Cause and Prevention Research	000	3	11/20/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2025 ( Subtotal = $173,220 )
2025	2025	VIRGINIA COMMONWEALTH UNIVERSITY	910 WEST FRANKLIN ST	RICHMOND	VA	23284	RICHMOND CITY	USA	Cancer Cause and Prevention Research	001	3	1/27/2025	NON-COMPETING CONTINUATION	$89,340
2025	2025	VIRGINIA COMMONWEALTH UNIVERSITY	910 WEST FRANKLIN ST	RICHMOND	VA	23284	RICHMOND CITY	USA	Cancer Cause and Prevention Research	002	3	2/12/2025	NON-COMPETING CONTINUATION	$0
2025	2023	UNIVERSITY OF FLORIDA	1523 UNION RD RM 207	GAINESVILLE	FL	32611	ALACHUA	USA	Cancer Cause and Prevention Research	000	1	1/17/2025	NEW	$83,880
														Subtotal = $173,220

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2023	UNIVERSITY OF FLORIDA	1523 UNION RD RM 207	GAINESVILLE	FL	32611	ALACHUA	USA	Cancer Cause and Prevention Research	000	1	2/26/2024	NEW	-$83,880
2024	2023	VIRGINIA COMMONWEALTH UNIVERSITY	910 WEST FRANKLIN ST	RICHMOND	VA	23284	RICHMOND CITY	USA	Cancer Cause and Prevention Research	001	2	2/26/2024	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$83,880
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $86,873 )
2023	2023	UNIVERSITY OF FLORIDA	1523 UNION RD RM 207	GAINESVILLE	FL	32611	ALACHUA	USA	Cancer Cause and Prevention Research	000	1	3/22/2023	NEW	$86,873
														Subtotal = $86,873

Grand Total All Awards = $260,093

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Developing a Young Adult-Mediated Intervention to Increase Colorectal Cancer Screening among Rural Screening Age-Eligible Adults

Award Number: R03CA270837

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 04/01/2023

PERIOD OF PERFORMANCE END DATE: 07/31/2026

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