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 | Issue Date FY: 2025 ( Subtotal = $23,645,281 ) (Continued on the next page) |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R35GM152058 | Ins and outs of the bioactive sphingolipid metabolite sphingosine-1-phosphate | 001 | 2 | NIH | 12/2/2024 | $349,313 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01DA060762 | pTau-related neuron and cognitive dysfunction in opioid-HIV comorbidity: Longitudinal and functional studies | 000 | 2 | NIH | 1/24/2025 | $627,826 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | T32GM148403 | VCU Initiative for Maximizing Student Development Program (IMSD) | 000 | 3 | NIH | 1/24/2025 | $270,995 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01DK107451 | The role of AEG-1 in NASH and NASH-HCC | 000 | 8 | NIH | 12/19/2024 | $543,969 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01AI174301 | Lentivirus-like particle specific delivery of Cas12 ribonucleoprotein (RNP) to HIV reservoir cells in vivo for an HIV cure | 002 | 3 | NIH | 12/12/2024 | $836,927 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R21CA289216 | Inhibition of diacylglycerol lipase α as a novel strategy to mitigate the nephrotoxicity of cisplatin | 000 | 1 | NIH | 12/27/2024 | $227,221 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01CA239714 | Multicenter Randomized Controlled Trial of Brief Behavioral Therapy for Cancer Related Insomnia | 000 | 7 | NIH | 12/27/2024 | $846,622 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R21CA277437 | Enhancing Tumor Cell Immunogenicity using Improved Molecules Targeting Chromatin Remodeling | 000 | 2 | NIH | 11/14/2024 | $163,199 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | U01AI169840 | PlzA, cyclic-di-GMP and the enzootic cycle for Lyme disease | 000 | 3 | NIH | 11/13/2024 | $669,937 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R61AI179996 | Development of genetic tools for Orientia tsutsugamushi | 000 | 2 | NIH | 12/6/2024 | $261,247 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R36DA062213 | A Mixed Methods Exploration of Prenatal Polysubstance Use | 000 | 1 | NIH | 1/16/2025 | $53,956 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | K99HL173554 | Mechanisms and Efficacy of Physical Activity to Reduce Cardiovascular Morbidity in Women with Breast Cancer | 000 | 1 | NIH | 1/10/2025 | $133,566 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01HL162991 | Metabolic perturbations in conventional dendritic cells modulate Tfh13 induction in asthmatic sensitization | 000 | 3 | NIH | 11/29/2024 | $540,579 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | UH3DA050311 | Mu Opioid Receptor Modulator Development to Treat Opioid Use Disorder | 000 | 5 | NIH | 1/16/2025 | $1,313,983 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01CA285692 | MYCN drives a druggable SUMOylation program in neuroblastoma | 000 | 2 | NIH | 12/20/2024 | $386,821 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R03AI180319 | Enzymology and Structure of Divergent Type 4 Pilus Extension ATPases | 000 | 2 | NIH | 11/25/2024 | $75,296 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01MH084894 | Function of GPCR heteromeric complexes in brain | 001 | 15 | NIH | 12/26/2024 | $447,909 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R21CA296516 | Inhibition of NLRP3 inflammasome for the treatment of Chemotherapy-induced peripheral neuropathy | 000 | 1 | NIH | 11/26/2024 | $181,448 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01DK107451 | The role of AEG-1 in NASH and NASH-HCC | 001 | 8 | NIH | 12/20/2024 | $41,044 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01CA259415 | Cause and Effect Relationships Between Glycation and the Ancestry Specific Tumor Stroma | 000 | 3 | NIH | 12/5/2024 | $381,112 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01AI167857 | Orientia tsutsugamushi Ank-host interactions in scrub typhus pathogenesis | 000 | 4 | NIH | 1/28/2025 | $555,206 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | K08HL155852 | Targeting Pannexin 1 as a Novel Mechanism for Arrhythmia and Fibrosis in Duchenne Cardiomyopathy | 000 | 5 | NIH | 1/21/2025 | $148,052 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | U24NS100673 | SIREN CORE-EM HUB ALLIANCE | 000 | 8 | NIH | 1/20/2025 | $138,040 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | U24NS100673 | SIREN CORE-EM HUB ALLIANCE | 000 | 8 | NIH | 1/20/2025 | $137,858 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01DE030667 | Dissecting the role of sialic acid and sialidase in the pathophysiology of Porphyromonas gingivalis | 000 | 5 | NIH | 1/27/2025 | $440,286 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R03CA270837 | Developing a Young Adult-Mediated Intervention to Increase Colorectal Cancer Screening among Rural Screening Age-Eligible Adults | 002 | 3 | NIH | 1/27/2025 | $89,340 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | UG1CA287017 | Virginia Cancer Screening Research Network Access Hub (Virginia CSRN Hub) | 000 | 2 | NIH | 12/5/2024 | $725,460 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01EB036599 | Ultrasensitive Ion-Selective Optodes for Self-Testing of Blood Electrolytes | 000 | 1 | NIH | 1/22/2025 | $260,467 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01CA290863 | Supportive Tailored Exercise Program for Survivors of Breast Cancer (STEPS-BC) | 000 | 1 | NIH | 1/31/2025 | $671,757 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01DK121131 | Sensory Cross-Activation in Bowel Dysfunction | 000 | 4 | NIH | 11/27/2024 | $388,707 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01EY033477 | Sustained release of fenofibrate for the treatment of diabetic retinopathy | 000 | 3 | NIH | 1/23/2025 | $23,288 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R21AI178143 | Mechanisms and consequences of human papillomavirus 16 E2 regulation of host gene transcription | 000 | 2 | NIH | 11/27/2024 | $188,241 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | F32AI174656 | Multifunctional roles of an Orientia tsutsugamushi nucleomodulin | 000 | 2 | NIH | 11/19/2024 | $74,284 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R35HL155651 | Managing Cardiac Toxicities of Cancer Therapy | 000 | 5 | NIH | 11/20/2024 | $698,624 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01CA281207 | Targeting cancer cachexia drivers using antibody-based approaches | 000 | 2 | NIH | 11/19/2024 | $375,887 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01HL163101 | Protein S-Palmitoylation in the Heart: Function and Regulation in Health and Disease | 000 | 3 | NIH | 11/18/2024 | $373,062 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01MH125902 | An Integrative Approach to the Etiology of Internalizing Disorders in the Lifelines Cohort | 000 | 4 | NIH | 11/19/2024 | $470,647 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | F31DA060668 | Novel Therapeutics for Treating Opioid Use Disorder | 000 | 1 | NIH | 12/10/2024 | $48,974 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01DA060724 | Opioid and non-opioid receptor mechanisms in neurons and glia underlying fentanyl and HIV comorbidity in the striatum | 001 | 2 | NIH | 3/24/2025 | $595,610 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R21DE033842 | Connecting liquid-liquid phase separation with super-enhancers and key oncogene transcription in HNSCC | 000 | 2 | NIH | 3/10/2025 | $170,435 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01CA260819 | A sequential therapeutic strategy of senescence induction and senolytics for elimination of surviving residual breast tumor cells | 000 | 5 | NIH | 3/3/2025 | $465,649 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | U01AA020912 | 4/11 Neuroimmune and extracellular matrix interactions in alcohol consumption | 000 | 15 | NIH | 3/4/2025 | $384,244 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01HL168133 | Antibacterial and Antithrombotic Catheter Lock Solutions Based on Controlled Release of Nitric Oxide | 000 | 3 | NIH | 3/11/2025 | $388,125 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R61CA278445 | Single-Molecule High-Confidence Detection of miRNA Cancer Biomarkers | 000 | 3 | NIH | 3/21/2025 | $189,927 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01GM143176 | Small molecule approach to activate human SIRT5 | 000 | 4 | NIH | 3/3/2025 | $327,365 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R21MH138949 | Studying normal and disease processes in brain with extracellular vesicles | 000 | 1 | NIH | 3/11/2025 | $271,688 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01DK137998 | An Integrated Lifestyle Intervention to Promote Cardiometabolic Health among Emerging Adult Women | 000 | 2 | NIH | 2/17/2025 | $279,450 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R01DA053153 | Opioid- and HIV-mediated effects on the integrity of the blood-brain barrier, on immune cell recruitment, and on antiretroviral penetration into the brain | 000 | 6 | NIH | 2/25/2025 | $442,098 |
| | 2025 | 2025 | VIRGINIA COMMONWEALTH UNIVERSITY | 910 WEST FRANKLIN ST | RICHMOND | VA | 23284-9005 | RICHMOND CITY | USA | R21DE034103 | Characterization of a conserved streptococcal membrane protein affecting manganese utilization | 000 | 1 | NIH | 3/27/2025 | $273,009 |
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